The two GAF domains in phosphodiesterase 2A have distinct roles in dimerization and in cGMP binding
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Cyclic nucleotide binding proteins in the Arabidopsis thaliana and Oryza sativa genomesPhosphodiesterase 2A forms a complex with the co-chaperone XAP2 and regulates nuclear translocation of the aryl hydrocarbon receptorMechanism for the allosteric regulation of phosphodiesterase 2A deduced from the X-ray structure of a near full-length constructBinding of cyclic nucleotides to phosphodiesterase 10A and 11A GAF domains does not stimulate catalytic activityAncient conserved domains shared by animal soluble guanylyl cyclases and bacterial signaling proteinsNovel Radioligands for Cyclic Nucleotide Phosphodiesterase Imaging with Positron Emission Tomography: An Update on Developments Since 2012Phosphorylation-Independent Regulation of the Diguanylate Cyclase WspRCrystal structure of the GAF-B domain from human phosphodiesterase 10A complexed with its ligand, cAMPSolution Structure of the cGMP Binding GAF Domain from Phosphodiesterase 5: INSIGHTS INTO NUCLEOTIDE SPECIFICITY, DIMERIZATION, AND cGMP-DEPENDENT CONFORMATIONAL CHANGEThe Structure of the GAF A Domain from Phosphodiesterase 6C Reveals Determinants of cGMP Binding, a Conserved Binding Surface, and a Large cGMP-dependent Conformational ChangeO2- and NO-Sensing Mechanism through the DevSR Two-Component System in Mycobacterium smegmatisThe structure of a complete phytochrome sensory module in the Pr ground stateChanges in Quaternary Structure in the Signaling Mechanisms of PAS Domains † , ‡Crystal Structures of YkuI and Its Complex with Second Messenger Cyclic Di-GMP Suggest Catalytic Mechanism of Phosphodiester Bond Cleavage by EAL DomainsStructural Insight into the Heme-based Redox Sensing by DosS from Mycobacterium tuberculosisConformation Changes, N-terminal Involvement, and cGMP Signal Relay in the Phosphodiesterase-5 GAF DomainCrystal structure of the GAF-B domain from human phosphodiesterase 5Structures of the PelD Cyclic Diguanylate Effector Involved in Pellicle Formation in Pseudomonas aeruginosa PAO1Structural Mechanism of GAF-Regulated σ54 Activators from Aquifex aeolicusCrystal structure of an HD-GYP domain cyclic-di-GMP phosphodiesterase reveals an enzyme with a novel trinuclear catalytic iron centreMolecular determinants for cyclic nucleotide binding to the regulatory domains of phosphodiesterase 2ACharacteristics of photoreceptor PDE (PDE6): similarities and differences to PDE5cAMP is a ligand for the tandem GAF domain of human phosphodiesterase 10 and cGMP for the tandem GAF domain of phosphodiesterase 11Cross-regulation of Phosphodiesterase 1 and Phosphodiesterase 2 Activities Controls Dopamine-mediated Striatal α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor TraffickingA novel two-component system found in Mycobacterium tuberculosisDevS, a heme-containing two-component oxygen sensor of Mycobacterium tuberculosisDcsbis (PA2771) from Pseudomonas aeruginosa is a highly active diguanylate cyclase with unique activity regulationEvolution of Vertebrate Phototransduction: Cascade ActivationPerception of the plant hormone ethylene: known-knowns and known-unknownsG protein signaling: insights from new structures.Phytochrome structure and signaling mechanisms.PDE5A suppression of acute beta-adrenergic activation requires modulation of myocyte beta-3 signaling coupled to PKG-mediated troponin I phosphorylation.Identification, characterization and subcellular localization of TcPDE1, a novel cAMP-specific phosphodiesterase from Trypanosoma cruzi.The signaling helix: a common functional theme in diverse signaling proteins.Cyclic nucleotide binding GAF domains from phosphodiesterases: structural and mechanistic insightsThe roles of cyclic nucleotide phosphodiesterases (PDEs) in steroidogenesis.Crystal structure of the tandem GAF domains from a cyanobacterial adenylyl cyclase: modes of ligand binding and dimerizationThe cyanobacterial tandem GAF domains from the cyaB2 adenylyl cyclase signal via both cAMP-binding sites.Nitric oxide/cGMP pathway signaling actively down-regulates α4β1-integrin affinity: an unexpected mechanism for inducing cell de-adhesion.Structural characterization of the rod cGMP phosphodiesterase 6.
P2860
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P2860
The two GAF domains in phosphodiesterase 2A have distinct roles in dimerization and in cGMP binding
description
2002 nî lūn-bûn
@nan
2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The two GAF domains in phospho ...... merization and in cGMP binding
@ast
The two GAF domains in phospho ...... merization and in cGMP binding
@en
The two GAF domains in phospho ...... merization and in cGMP binding
@nl
type
label
The two GAF domains in phospho ...... merization and in cGMP binding
@ast
The two GAF domains in phospho ...... merization and in cGMP binding
@en
The two GAF domains in phospho ...... merization and in cGMP binding
@nl
prefLabel
The two GAF domains in phospho ...... merization and in cGMP binding
@ast
The two GAF domains in phospho ...... merization and in cGMP binding
@en
The two GAF domains in phospho ...... merization and in cGMP binding
@nl
P2093
P2860
P3181
P356
P1476
The two GAF domains in phospho ...... merization and in cGMP binding
@en
P2093
Albert Y Wu
Joseph A Beavo
Natalie A Glavas
Sergio E Martinez
Stewart Turley
Wim G J Hol
Xiao-Bo Tang
P2860
P304
P3181
P356
10.1073/PNAS.192374899
P407
P577
2002-10-01T00:00:00Z