Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha.
about
HSP72 protects cells from ER stress-induced apoptosis via enhancement of IRE1alpha-XBP1 signaling through a physical interactionHypoxia stimulates migration of breast cancer cells via the PERK/ATF4/LAMP3-arm of the unfolded protein responseThe unfolded protein response induces the angiogenic switch in human tumor cells through the PERK/ATF4 pathwayThe endoplasmic reticulum stress response in aging and age-related diseasesGene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control.p58IPK is an inhibitor of the eIF2α kinase GCN2 and its localization and expression underpin protein synthesis and ER processing capacityERdj5 sensitizes neuroblastoma cells to endoplasmic reticulum stress-induced apoptosisBBF2H7, a novel transmembrane bZIP transcription factor, is a new type of endoplasmic reticulum stress transducerFibronectin controls cap-dependent translation through beta1 integrin and eukaryotic initiation factors 4 and 2 coordinated pathwaysHypoxia inhibits protein synthesis through a 4E-BP1 and elongation factor 2 kinase pathway controlled by mTOR and uncoupled in breast cancer cellsOGFOD1, a novel modulator of eukaryotic translation initiation factor 2alpha phosphorylation and the cellular response to stressObstructive sleep apnea syndrome and fatty liver: association or causal link?The acute neurotoxicity of mefloquine may be mediated through a disruption of calcium homeostasis and ER function in vitroHypoxic stress suppresses RNA polymerase III recruitment and tRNA gene transcription in cardiomyocytes.Cancer Microenvironment and Endoplasmic Reticulum Stress ResponseHypoxia signaling pathways: modulators of oxygen-related organelles'Biologic memory' in response to acute kidney injury: cytoresistance, toll-like receptor hyper-responsiveness and the onset of progressive renal diseaseER stress-induced cell death mechanismsRegulation of stem cell differentiation in adipose tissue by chronic inflammationMolecular Connections between Cancer Cell Metabolism and the Tumor MicroenvironmentOxidative stress, unfolded protein response, and apoptosis in developmental toxicityTumor progression and the different faces of the PERK kinasePost-transcriptional control of human maxiK potassium channel activity and acute oxygen sensitivity by chronic hypoxiaInflammation and cellular stress: a mechanistic link between immune-mediated and metabolically driven pathologiesMitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M) is a pro-survival, endoplasmic reticulum (ER) stress response gene involved in tumor cell adaptation to nutrient availabilityProtein quality control and metabolism: bidirectional control in the heartPERK Integrates Oncogenic Signaling and Cell Survival During Cancer DevelopmentModulation of the Akt pathway reveals a novel link with PERK/eIF2α, which is relevant during hypoxiaThe cellular oxygen tension regulates expression of the endoplasmic oxidoreductase ERO1-LalphaCharacterization of stanniocalcin 2, a novel target of the mammalian unfolded protein response with cytoprotective propertiesPERK and GCN2 contribute to eIF2alpha phosphorylation and cell cycle arrest after activation of the unfolded protein response pathwaySteroid and oxygen effects on eIF4F complex, mTOR, and ENaC translation in fetal lung epitheliaMumps Virus Induces Protein-Kinase-R-Dependent Stress Granules, Partly Suppressing Type III Interferon Production.Gene expression changes leading extreme alkaline tolerance in Amur ide (Leuciscus waleckii) inhabiting soda lake.Dormancy of cancer cells with suppression of AKT activity contributes to survival in chronic hypoxia.Use of culture geometry to control hypoxia-induced vascular endothelial growth factor secretion from adipose-derived stem cells: optimizing a cell-based approach to drive vascular growthSleep, plasticity and the pathophysiology of neurodevelopmental disorders: the potential roles of protein synthesis and other cellular processes.Zinc finger nuclease mediated knockout of ADP-dependent glucokinase in cancer cell lines: effects on cell survival and mitochondrial oxidative metabolism.Novel tumor antigens elicit anti-tumor humoral immune reactions in a subset of patients with polycythemia veraSurviving endoplasmic reticulum stress is coupled to altered chondrocyte differentiation and function
P2860
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P2860
Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha.
description
2002 nî lūn-bûn
@nan
2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Regulation of protein synthesi ...... on initiation factor eIF2alpha
@nl
Regulation of protein synthesi ...... n initiation factor eIF2alpha.
@ast
Regulation of protein synthesi ...... n initiation factor eIF2alpha.
@en
type
label
Regulation of protein synthesi ...... on initiation factor eIF2alpha
@nl
Regulation of protein synthesi ...... n initiation factor eIF2alpha.
@ast
Regulation of protein synthesi ...... n initiation factor eIF2alpha.
@en
prefLabel
Regulation of protein synthesi ...... on initiation factor eIF2alpha
@nl
Regulation of protein synthesi ...... n initiation factor eIF2alpha.
@ast
Regulation of protein synthesi ...... n initiation factor eIF2alpha.
@en
P2093
P2860
P50
P921
P3181
P1476
Regulation of protein synthesi ...... n initiation factor eIF2alpha.
@en
P2093
Alan Diehl
Antonis Koromilas
Christine Naczki
Constantinos Koumenis
Sally Rastani
P2860
P304
P3181
P356
10.1128/MCB.22.21.7405-7416.2002
P407
P577
2002-11-01T00:00:00Z