Nicotinic acid-adenine dinucleotide phosphate-sensitive calcium stores initiate insulin signaling in human beta cells.
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RyR2 and calpain-10 delineate a novel apoptosis pathway in pancreatic isletsNicotinic acid adenine dinucleotide phosphate regulates skeletal muscle differentiation via action at two-pore channelsCarboxypeptidase E mediates palmitate-induced beta-cell ER stress and apoptosisIdentification of a chemical probe for NAADP by virtual screeningInsulin protects islets from apoptosis via Pdx1 and specific changes in the human islet proteomeStatistical approaches and software for clustering islet cell functional heterogeneity.Arginine Thiazolidine Carboxylate Stimulates Insulin Secretion through Production of Ca2+-Mobilizing Second Messengers NAADP and cADPR in Pancreatic IsletsReconstitution and characterization of a nicotinic acid adenine dinucleotide phosphate (NAADP)-sensitive Ca2+ release channel from liver lysosomes of ratsPancreatic β-cell Raf-1 is required for glucose tolerance, insulin secretion, and insulin 2 transcriptionTPC2 proteins mediate nicotinic acid adenine dinucleotide phosphate (NAADP)- and agonist-evoked contractions of smooth muscleHigh-content screening identifies a role for Na(+) channels in insulin productionHigh resolution structural evidence suggests the Sarcoplasmic Reticulum forms microdomains with Acidic Stores (lysosomes) in the heartIs dynamic autocrine insulin signaling possible? A mathematical model predicts picomolar concentrations of extracellular monomeric insulin within human pancreatic islets.Acute insulin signaling in pancreatic beta-cells is mediated by multiple Raf-1 dependent pathwaysTwo-pore channels for integrative Ca signaling.Ubiquitin C-terminal hydrolase L1 is required for pancreatic beta cell survival and function in lipotoxic conditions.Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) and Endolysosomal Two-pore Channels Modulate Membrane Excitability and Stimulus-Secretion Coupling in Mouse Pancreatic β Cells.Effects of insulin on human pancreatic cancer progression modeled in vitroTwo-Pore Channels: Lessons from Mutant Mouse ModelsCa-induced Ca Release from Internal Stores in INS-1 Rat Insulinoma Cells.Lipopolysaccharide induces endoplasmic store Ca2+-dependent inflammatory responses in lung microvesselsGlucose and endoplasmic reticulum calcium channels regulate HIF-1beta via presenilin in pancreatic beta-cells.Nicotinic acid adenine dinucleotide phosphate (NAADP)-mediated calcium signaling.Calcium signalling by nicotinic acid adenine dinucleotide phosphate (NAADP).Regulation of Glucokinase by Intracellular Calcium Levels in Pancreatic β CellsInsulin stimulates primary beta-cell proliferation via Raf-1 kinase.Ranking candidate genes in rat models of type 2 diabetes.Autocrine/paracrine function of nicotinic acid adenine dinucleotide phosphate (NAADP) for glucose homeostasis in pancreatic β-cells and adipocytes.Cyclic ADP-Ribose and NAADP in Vascular Regulation and Diseases.Cyclic ADP-ribose and NAADP: fraternal twin messengers for calcium signaling.Physiological roles of NAADP-mediated Ca2+ signaling.Nanospaces between endoplasmic reticulum and mitochondria as control centres of pancreatic β-cell metabolism and survival.Roles of cADPR and NAADP in pancreatic cells.Autocrine regulation of insulin secretion.Preferential Coupling of the NAADP Pathway to Exocytosis in T-Cells.An emerging role for NAADP-mediated Ca2+ signaling in the pancreatic β-cell.Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death.Synergistic regulation of endogenous TRPM2 channels by adenine dinucleotides in primary human neutrophils.Defective insulin secretion and increased susceptibility to experimental diabetes are induced by reduced Akt activity in pancreatic islet beta cells.Lysosomal cholesterol accumulation in macrophages leading to coronary atherosclerosis in CD38(-/-) mice.
P2860
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P2860
Nicotinic acid-adenine dinucleotide phosphate-sensitive calcium stores initiate insulin signaling in human beta cells.
description
2002 nî lūn-bûn
@nan
2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Nicotinic acid-adenine dinucle ...... signaling in human beta cells
@nl
Nicotinic acid-adenine dinucle ...... signaling in human beta cells.
@ast
Nicotinic acid-adenine dinucle ...... signaling in human beta cells.
@en
type
label
Nicotinic acid-adenine dinucle ...... signaling in human beta cells
@nl
Nicotinic acid-adenine dinucle ...... signaling in human beta cells.
@ast
Nicotinic acid-adenine dinucle ...... signaling in human beta cells.
@en
prefLabel
Nicotinic acid-adenine dinucle ...... signaling in human beta cells
@nl
Nicotinic acid-adenine dinucle ...... signaling in human beta cells.
@ast
Nicotinic acid-adenine dinucle ...... signaling in human beta cells.
@en
P2860
P356
P1476
Nicotinic acid-adenine dinucle ...... signaling in human beta cells.
@en
P2093
James D Johnson
Stanley Misler
P2860
P304
14566-14571
P356
10.1073/PNAS.222099799
P407
P577
2002-10-15T00:00:00Z