PPARdelta regulates glucose metabolism and insulin sensitivity - Test2 - elhamkhani - TriplyDB

PPARdelta regulates glucose metabolism and insulin sensitivity

PPARdelta regulates glucose metabolism and insulin sensitivity

http://www.wikidata.org/entity/Q24541495

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PPARs and the cardiovascular system Metabolic shifts due to long-term caloric restriction revealed in nonhuman primates Quantitative expression patterns of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) protein in mice Mechanisms underlying the resistance to diet-induced obesity in germ-free mice Orphan nuclear receptors and the regulation of nutrient metabolism: understanding obesity Transcriptional repression of mitochondrial function in aging: a novel role for the silencing mediator of retinoid and thyroid hormone receptors co-repressor Assay of the multiple energy-producing pathways of mammalian cells Structural Basis for Ligand Regulation of the Fatty Acid-binding Protein 5, Peroxisome Proliferator-activated Receptor / (FABP5-PPAR / ) Signaling Pathway PPARγ as a therapeutic target to rescue mitochondrial function in neurological disease Fibrates, glitazones, and peroxisome proliferator-activated receptors Scaffold-based pan-agonist design for the PPARα, PPARβ and PPARγ receptors The PPARdelta agonist, GW501516, promotes fatty acid oxidation but has no direct effect on glucose utilisation or insulin sensitivity in rat L6 skeletal muscle cells An ethanol extract of Artemisia iwayomogi activates PPARδ leading to activation of fatty acid oxidation in skeletal muscle Increased systemic glucose tolerance with increased muscle glucose uptake in transgenic mice overexpressing RXRγ in skeletal muscle Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver PPARs in obesity-induced T2DM, dyslipidaemia and NAFLD.Mimetics of hormetic agents: stress-resistance triggers Retinoic acid actions through mammalian nuclear receptors.Hypermetabolism, hyperphagia, and reduced adiposity in tankyrase-deficient mice.PPARdelta-mediated antiinflammatory mechanisms inhibit angiotensin II-accelerated atherosclerosis The role of the small intestine in the development of dietary fat-induced obesity and insulin resistance in C57BL/6J mice.Increased hepatic oxidative metabolism distinguishes the action of Peroxisome proliferator-activated receptor delta from Peroxisome proliferator-activated receptor gamma in the ob/ob mouse.Genetic ablation of calcium-independent phospholipase A2gamma prevents obesity and insulin resistance during high fat feeding by mitochondrial uncoupling and increased adipocyte fatty acid oxidation.The natural protective mechanism against hyperglycemia in vascular endothelial cells: roles of the lipid peroxidation product 4-hydroxydodecadienal and peroxisome proliferator-activated receptor delta A maternal "junk food" diet in pregnancy and lactation promotes nonalcoholic Fatty liver disease in rat offspring The role of mitochondria in the pathophysiology of skeletal muscle insulin resistance.PPARδ activation attenuates hepatic steatosis in Ldlr-/- mice by enhanced fat oxidation, reduced lipogenesis, and improved insulin sensitivity VLDL hydrolysis by hepatic lipase regulates PPARδ transcriptional responses Genetic ablation of steroid receptor coactivator-3 promotes PPAR-beta-mediated alternative activation of microglia in experimental autoimmune encephalomyelitis.Global metabolic effects of glycerol kinase overexpression in rat hepatoma cells.Dual peroxisome proliferator-activated receptor α/δ agonist GFT505 improves hepatic and peripheral insulin sensitivity in abdominally obese subjects.GW501516, a PPARδ agonist, ameliorates tubulointerstitial inflammation in proteinuric kidney disease via inhibition of TAK1-NFκB pathway in mice.GFT505 for the treatment of nonalcoholic steatohepatitis and type 2 diabetes.The dual peroxisome proliferator-activated receptor alpha/delta agonist GFT505 exerts anti-diabetic effects in db/db mice without peroxisome proliferator-activated receptor gamma-associated adverse cardiac effects.Angiotensin II receptor blocker telmisartan enhances running endurance of skeletal muscle through activation of the PPAR-δ/AMPK pathway.Cellular and pharmacological selectivity of the peroxisome proliferator-activated receptor-beta/delta antagonist GSK3787.Signaling and cytotoxic functions of 4-hydroxyalkenals.Nutritional regulation of bile acid metabolism is associated with improved pathological characteristics of the metabolic syndrome.Effects of the new dual PPAR α/δ agonist GFT505 on lipid and glucose homeostasis in abdominally obese patients with combined dyslipidemia or impaired glucose metabolism.Associations of type 2 diabetes with common variants in PPARD and the modifying effect of vitamin D among middle-aged and elderly Chinese

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P2860

PPARdelta regulates glucose metabolism and insulin sensitivity

http://www.wikidata.org/entity/Q24541495

description

2006 nî lūn-bûn

@nan

2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2006年の論文

@ja

2006年論文

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2006年論文

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2006年論文

@zh-hk

2006年論文

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2006年論文

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2006年论文

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name

PPARdelta regulates glucose metabolism and insulin sensitivity

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PPARdelta regulates glucose metabolism and insulin sensitivity

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PPARdelta regulates glucose metabolism and insulin sensitivity

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type

label

PPARdelta regulates glucose metabolism and insulin sensitivity

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PPARdelta regulates glucose metabolism and insulin sensitivity

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PPARdelta regulates glucose metabolism and insulin sensitivity

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prefLabel

PPARdelta regulates glucose metabolism and insulin sensitivity

@ast

PPARdelta regulates glucose metabolism and insulin sensitivity

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PPARdelta regulates glucose metabolism and insulin sensitivity

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PNAS.0511253103

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Proceedings of the National Academy of Sciences of the United States of America

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PPARdelta regulates glucose metabolism and insulin sensitivity

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Andrea Hevener

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Chih-Hao Lee

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Frank J Gonzalez

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Heonjoong Kang

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Isaac Mehl

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Jeffrey M Peters

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Jungyeob Ham

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Ling-Wa Chong

http://www.w3.org/2001/XMLSchema#string

Peter Olson

http://www.w3.org/2001/XMLSchema#string

P2860

Role of LXRs in control of lipogenesis

Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors alpha and gamma

Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor beta(delta)

Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting

Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta

A selective peroxisome proliferator-activated receptor delta agonist promotes reverse cholesterol transport

Software and methods for oligonucleotide and cDNA array data analysis.

Regulation of muscle fiber type and running endurance by PPARdelta

A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: the PPARalpha-null mouse as a model of fatty acid oxidation disorders

PPAR gamma is required for the differentiation of adipose tissue in vivo and in vitro

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10.1073/PNAS.0511253103

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9

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103

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Jerrold M. Olefsky

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