HSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparin-bound growth factors and chemokines: effects on VEGF, FGF-1, and SDF-1.
about
Secreted sulfatases Sulf1 and Sulf2 have overlapping yet essential roles in mouse neonatal survivalCharacterization of the human sulfatase Sulf1 and its high affinity heparin/heparan sulfate interaction domainDirect detection of HSulf-1 and HSulf-2 activities on extracellular heparan sulfate and their inhibition by PI-88Functional consequences of the subdomain organization of the sulfsHSulf-1 modulates FGF2- and hypoxia-mediated migration and invasion of breast cancer cellsSulf-2, a proangiogenic heparan sulfate endosulfatase, is upregulated in breast cancerSulfatase 2 up-regulates glypican 3, promotes fibroblast growth factor signaling, and decreases survival in hepatocellular carcinomaExpression of novel extracellular sulfatases Sulf-1 and Sulf-2 in normal and osteoarthritic articular cartilageGene trap disruption of the mouse heparan sulfate 6-O-endosulfatase gene, Sulf2Heparan sulfate 6-O-endosulfatases: discrete in vivo activities and functional co-operativityGlycosaminoglycan glycomics using mass spectrometryRemodelling the extracellular matrix in development and diseaseFunctional aspects of the interaction between interleukin-8 and sulfated glycosaminoglycansHeparan sulfate proteoglycans in the control of B cell development and the pathogenesis of multiple myelomaCorrelation between the methylation of SULF2 and WRN promoter and the irinotecan chemosensitivity in gastric cancerConcomitant promoter methylation of multiple genes in lung adenocarcinomas from current, former and never smokersWT1-dependent sulfatase expression maintains the normal glomerular filtration barrierA chemokine self-presentation mechanism involving formation of endothelial surface microstructuresExtracellular sulfatases, elements of the Wnt signaling pathway, positively regulate growth and tumorigenicity of human pancreatic cancer cellsHuman Sulfatase 2 inhibits in vivo tumor growth of MDA-MB-231 human breast cancer xenografts.Regulation of intracellular signaling by extracellular glycan remodeling.Ovarian cancer cell heparan sulfate 6-O-sulfotransferases regulate an angiogenic program induced by heparin-binding epidermal growth factor (EGF)-like growth factor/EGF receptor signalingSynthetic di-sulfated iduronic acid attenuates asthmatic response by blocking T-cell recruitment to inflammatory sitesCharacterizing molecular diffusion in the lens capsuleDesign and synthesis of biphenyl and biphenyl ether inhibitors of sulfatases.Matrix regulators in neural stem cell functions.Stimulation of chondrocyte hypertrophy by chemokine stromal cell-derived factor 1 in the chondro-osseous junction during endochondral bone formationDetermination of genes and microRNAs involved in the resistance to fludarabine in vivo in chronic lymphocytic leukemiaSpecific sides to multifaceted glycosaminoglycans are observed in embryonic development.Organ-specific sulfation patterns of heparan sulfate generated by extracellular sulfatases Sulf1 and Sulf2 in miceMYCN-dependent expression of sulfatase-2 regulates neuroblastoma cell survival.Dendritic cell chemotaxis in 3D under defined chemokine gradients reveals differential response to ligands CCL21 and CCL19.The left-right Pitx2 pathway drives organ-specific arterial and lymphatic development in the intestine.Hypoxia negatively regulates heparan sulfatase 2 expression in renal cancer cell lines.Proteases involved in cartilage matrix degradation in osteoarthritis.Modular synthesis of heparin-related tetra-, hexa- and octasaccharides with differential o-6 protections: programming for regiodefined 6-o-modifications.Sulfatase 1 and sulfatase 2 in hepatocellular carcinoma: associated signaling pathways, tumor phenotypes, and survival.Heparan sulfate sulfatase SULF2 regulates PDGFRα signaling and growth in human and mouse malignant gliomaSynergistic Binding of Vascular Endothelial Growth Factor-A and Its Receptors to Heparin Selectively Modulates Complex Affinity.SULF2 methylation is prognostic for lung cancer survival and increases sensitivity to topoisomerase-I inhibitors via induction of ISG15.
P2860
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P2860
HSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparin-bound growth factors and chemokines: effects on VEGF, FGF-1, and SDF-1.
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
HSulf-2, an extracellular endo ...... ects on VEGF, FGF-1, and SDF-1
@nl
HSulf-2, an extracellular endo ...... cts on VEGF, FGF-1, and SDF-1.
@ast
HSulf-2, an extracellular endo ...... cts on VEGF, FGF-1, and SDF-1.
@en
HSulf-2, an extracellular endo ...... cts on VEGF, FGF-1, and SDF-1.
@en-gb
type
label
HSulf-2, an extracellular endo ...... ects on VEGF, FGF-1, and SDF-1
@nl
HSulf-2, an extracellular endo ...... cts on VEGF, FGF-1, and SDF-1.
@ast
HSulf-2, an extracellular endo ...... cts on VEGF, FGF-1, and SDF-1.
@en
HSulf-2, an extracellular endo ...... cts on VEGF, FGF-1, and SDF-1.
@en-gb
prefLabel
HSulf-2, an extracellular endo ...... ects on VEGF, FGF-1, and SDF-1
@nl
HSulf-2, an extracellular endo ...... cts on VEGF, FGF-1, and SDF-1.
@ast
HSulf-2, an extracellular endo ...... cts on VEGF, FGF-1, and SDF-1.
@en
HSulf-2, an extracellular endo ...... cts on VEGF, FGF-1, and SDF-1.
@en-gb
P2093
P2860
P3181
P356
P1433
P1476
HSulf-2, an extracellular endo ...... cts on VEGF, FGF-1, and SDF-1.
@en
P2093
Annette Bistrup
Jessica Li
John Gallagher
Kenji Uchimura
Megumi Morimoto-Tomita
Steven D Rosen
P2860
P2888
P3181
P356
10.1186/1471-2091-7-2
P407
P577
2006-01-17T00:00:00Z
P5875
P6179
1018351024