Interaction of KCNE subunits with the KCNQ1 K+ channel pore - Test2 - elhamkhani - TriplyDB

Interaction of KCNE subunits with the KCNQ1 K+ channel pore

Interaction of KCNE subunits with the KCNQ1 K+ channel pore

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Distinct subdomains of the KCNQ1 S6 segment determine channel modulation by different KCNE subunits Intracellular domains interactions and gated motions of I(KS) potassium channel subunits Dynamic partnership between KCNQ1 and KCNE1 and influence on cardiac IKs current amplitude by KCNE2 The KCNQ1 channel - remarkable flexibility in gating allows for functional versatility KCNQ1 channel modulation by KCNE proteins via the voltage-sensing domain Structure of KCNE1 and Implications for How It Modulates the KCNQ1 Potassium Channel † ‡KCNE1 and KCNE3 stabilize and/or slow voltage sensing S4 segment of KCNQ1 channel Structural basis of slow activation gating in the cardiac I Ks channel complex Preparation, functional characterization, and NMR studies of human KCNE1, a voltage-gated potassium channel accessory subunit associated with deafness and long QT syndrome KCNE2 and the K (+) channel: the tail wagging the dog A shared mechanism for lipid- and beta-subunit-coordinated stabilization of the activated K+ channel voltage sensor Structural correlates of selectivity and inactivation in potassium channels.High-risk long QT syndrome mutations in the Kv7.1 (KCNQ1) pore disrupt the molecular basis for rapid K(+) permeation A double-point mutation in the selectivity filter site of the KCNQ1 potassium channel results in a severe phenotype, LQT1, of long QT syndrome.Functional interactions between KCNE1 C-terminus and the KCNQ1 channel.Differential modulations of KCNQ1 by auxiliary proteins KCNE1 and KCNE2 Mechanisms of disease pathogenesis in long QT syndrome type 5 Identification of a protein-protein interaction between KCNE1 and the activation gate machinery of KCNQ1 N-terminal arginines modulate plasma-membrane localization of Kv7.1/KCNE1 channel complexes.Allosteric features of KCNQ1 gating revealed by alanine scanning mutagenesis.KCNQ1/KCNE1 assembly, co-translation not required.Extracellular potassium inhibits Kv7.1 potassium channels by stabilizing an inactivated state.KCNQ1 subdomains involved in KCNE modulation revealed by an invertebrate KCNQ1 orthologue.Partial restoration of the long QT syndrome associated KCNQ1 A341V mutant by the KCNE1 β-subunit Reconstitution of KCNE1 into lipid bilayers: comparing the structural, dynamic, and activity differences in micelle and vesicle environments Serial perturbation of MinK in IKs implies an alpha-helical transmembrane span traversing the channel corpus.A distinct three-helix centipede toxin SSD609 inhibits I(ks) channels by interacting with the KCNE1 auxiliary subunit.Drosophila TRP channels require a protein with a distinctive motif encoded by the inaF locus.The role of S4 charges in voltage-dependent and voltage-independent KCNQ1 potassium channel complexes.KCNE peptides differently affect voltage sensor equilibrium and equilibration rates in KCNQ1 K+ channels KCNE3 acts by promoting voltage sensor activation in KCNQ1.Dysfunctional potassium channel subunit interaction as a novel mechanism of long QT syndrome.KCNQ1 and KCNE1 in the IKs channel complex make state-dependent contacts in their extracellular domains.Voltage-dependent C-type inactivation in a constitutively open K+ channel A novel transgenic rabbit model with reduced repolarization reserve: long QT syndrome caused by a dominant-negative mutation of the KCNE1 gene.KCNE genetics and pharmacogenomics in cardiac arrhythmias: much ado about nothing?KCNE1 and KCNE3: The yin and yang of voltage-gated K(+) channel regulation Location of KCNE1 relative to KCNQ1 in the I(KS) potassium channel by disulfide cross-linking of substituted cysteines.Structural basis for KCNE3 modulation of potassium recycling in epithelia DEER EPR measurements for membrane protein structures via bifunctional spin labels and lipodisq nanoparticles

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Interaction of KCNE subunits with the KCNQ1 K+ channel pore

http://www.wikidata.org/entity/Q24548322

description

2006 nî lūn-bûn

@nan

2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի փետրվարին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

Interaction of KCNE subunits with the KCNQ1 K+ channel pore

@ast

Interaction of KCNE subunits with the KCNQ1 K+ channel pore

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Interaction of KCNE subunits with the KCNQ1 K+ channel pore

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type

label

Interaction of KCNE subunits with the KCNQ1 K+ channel pore

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Interaction of KCNE subunits with the KCNQ1 K+ channel pore

@en

Interaction of KCNE subunits with the KCNQ1 K+ channel pore

@nl

prefLabel

Interaction of KCNE subunits with the KCNQ1 K+ channel pore

@ast

Interaction of KCNE subunits with the KCNQ1 K+ channel pore

@en

Interaction of KCNE subunits with the KCNQ1 K+ channel pore

@nl

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JPHYSIOL.2005.100644

P1433

The Journal of Physiology

P1476

Interaction of KCNE subunits with the KCNQ1 K+ channel pore

@en

P2093

Geoffrey W Abbott

http://www.w3.org/2001/XMLSchema#string

Gianina Panaghie

http://www.w3.org/2001/XMLSchema#string

Kwok-Keung Tai

http://www.w3.org/2001/XMLSchema#string

P2860

A constitutively open potassium channel formed by KCNQ1 and KCNE3

The Structure of the Potassium Channel: Molecular Basis of K+ Conduction and Selectivity

X-ray structure of a voltage-dependent K+ channel

KCNE2 confers background current characteristics to the cardiac KCNQ1 potassium channel

KCNE5 induces time- and voltage-dependent modulation of the KCNQ1 current.

Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias

KvLQT1, a voltage-gated potassium channel responsible for human cardiac arrhythmias

Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel

KCNE4 is an inhibitory subunit to the KCNQ1 channel

Voltage-dependent inactivation of the human K+ channel KvLQT1 is eliminated by association with minimal K+ channel (minK) subunits

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455-67

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scholarly article

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3589554

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10.1113/JPHYSIOL.2005.100644

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P433

Pt 3

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570

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2006-02-01T00:00:00Z

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7461260

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16308347

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1479883

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