Hec1p, an evolutionarily conserved coiled-coil protein, modulates chromosome segregation through interaction with SMC proteins
about
The Ndc80p complex from Saccharomyces cerevisiae contains conserved centromere components and has a function in chromosome segregationA potential role for human cohesin in mitotic spindle aster assemblyHec1 sequentially recruits Zwint-1 and ZW10 to kinetochores for faithful chromosome segregation and spindle checkpoint controlMolecular analysis of kinetochore architecture in fission yeastRetinoblastoma protein enhances the fidelity of chromosome segregation mediated by hsHec1pThe cohesin complex: sequence homologies, interaction networks and shared motifsCondensin binding at distinct and specific chromosomal sites in the Saccharomyces cerevisiae genome.Pds5p is an essential chromosomal protein required for both sister chromatid cohesion and condensation in Saccharomyces cerevisiae.The budding yeast proteins Spc24p and Spc25p interact with Ndc80p and Nuf2p at the kinetochore and are important for kinetochore clustering and checkpoint control.Phosphorylation of the mitotic regulator protein Hec1 by Nek2 kinase is essential for faithful chromosome segregation.Molecular organization of the Ndc80 complex, an essential kinetochore component.Targeting tumor suppressor networks for cancer therapeutics.Beyond the ABCs of CKC and SCC. Do centromeres orchestrate sister chromatid cohesion or vice versa?The APC/C Ubiquitin Ligase: From Cell Biology to TumorigenesisSAC-ing mitotic errors: how the spindle assembly checkpoint (SAC) plays defense against chromosome mis-segregation.Nuf2 is required for chromosome segregation during mouse oocyte meiotic maturationKiss and break up--a safe passage to anaphase in mitosis and meiosis.Spindle checkpoint proteins and chromosome-microtubule attachment in budding yeast.Pocket protein function in melanocyte homeostasis and neoplasia.Complementary interhelical interactions between three buried Glu-Lys pairs within three heptad repeats are essential for Hec1-Nuf2 heterodimerization and mitotic progression.Inhibition of Hec1 as a novel approach for treatment of primary liver cancer.High-throughput immunofluorescence microscopy using yeast spheroplast cell-based microarraysPathway redundancy and protein essentiality revealed in the Saccharomyces cerevisiae interaction networks.Ndc80 regulates meiotic spindle organization, chromosome alignment, and cell cycle progression in mouse oocytes.Identification of a new transcript specifically expressed in mouse spermatocytes: mmrp2.Hec1 inhibition alters spindle morphology and chromosome alignment in porcine oocytes.Maize NDC80 is a constitutive feature of the central kinetochore.Melanocytes in conditional Rb-/- mice are normal in vivo but exhibit proliferation and pigmentation defects in vitro.
P2860
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P2860
Hec1p, an evolutionarily conserved coiled-coil protein, modulates chromosome segregation through interaction with SMC proteins
description
1999 nî lūn-bûn
@nan
1999 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Hec1p, an evolutionarily conse ...... interaction with SMC proteins
@ast
Hec1p, an evolutionarily conse ...... interaction with SMC proteins
@en
Hec1p, an evolutionarily conse ...... interaction with SMC proteins
@nl
type
label
Hec1p, an evolutionarily conse ...... interaction with SMC proteins
@ast
Hec1p, an evolutionarily conse ...... interaction with SMC proteins
@en
Hec1p, an evolutionarily conse ...... interaction with SMC proteins
@nl
prefLabel
Hec1p, an evolutionarily conse ...... interaction with SMC proteins
@ast
Hec1p, an evolutionarily conse ...... interaction with SMC proteins
@en
Hec1p, an evolutionarily conse ...... interaction with SMC proteins
@nl
P2093
P2860
P356
P1476
Hec1p, an evolutionarily conse ...... interaction with SMC proteins
@en
P2093
P2860
P304
P356
10.1128/MCB.19.8.5417
P407
P577
1999-08-01T00:00:00Z