Cloning, characterization, and expression of a novel Zn2+-binding FYVE finger-containing phosphoinositide kinase in insulin-sensitive cells
about
PIKfyve controls fluid phase endocytosis but not recycling/degradation of endocytosed receptors or sorting of procathepsin D by regulating multivesicular body morphogenesisEndofin recruits TOM1 to endosomesThe mammalian phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) regulates endosome-to-TGN retrograde transport.Kinesin adapter JLP links PIKfyve to microtubule-based endosome-to-trans-Golgi network traffic of furinA mammalian ortholog of Saccharomyces cerevisiae Vac14 that associates with and up-regulates PIKfyve phosphoinositide 5-kinase activityInhibition of the PtdIns(5) kinase PIKfyve disrupts intracellular replication of Salmonella.Assembly of a Fab1 phosphoinositide kinase signaling complex requires the Fig4 phosphoinositide phosphatasePIKfyve-ArPIKfyve-Sac3 core complex: contact sites and their consequence for Sac3 phosphatase activity and endocytic membrane homeostasisPIKfyve: Partners, significance, debates and paradoxesArPIKfyve-PIKfyve interaction and role in insulin-regulated GLUT4 translocation and glucose transport in 3T3-L1 adipocytesArPIKfyve homomeric and heteromeric interactions scaffold PIKfyve and Sac3 in a complex to promote PIKfyve activity and functionalityPhosphoinositides: tiny lipids with giant impact on cell regulationPhosphoinositides in the mammalian endo-lysosomal networkIdentification of mammalian Vps24p as an effector of phosphatidylinositol 3,5-bisphosphate-dependent endosome compartmentalizationPhosphatidylinositol 3-phosphate-interacting domains in PIKfyve. Binding specificity and role in PIKfyve. Endomenbrane localizationActive PIKfyve associates with and promotes the membrane attachment of the late endosome-to-trans-Golgi network transport factor Rab9 effector p40Mammalian cell morphology and endocytic membrane homeostasis require enzymatically active phosphoinositide 5-kinase PIKfyveThe phox homology (PX) domain-dependent, 3-phosphoinositide-mediated association of sorting nexin-1 with an early sorting endosomal compartment is required for its ability to regulate epidermal growth factor receptor degradationPIKfyve negatively regulates exocytosis in neurosecretory cellsLocalized PtdIns 3,5-P2 synthesis to regulate early endosome dynamics and fusionWortmannin-sensitive trafficking steps in the endocytic pathway in rat liver endothelial cellsLocalization and insulin-regulated relocation of phosphoinositide 5-kinase PIKfyve in 3T3-L1 adipocytesComplementation analysis in PtdInsP kinase-deficient yeast mutants demonstrates that Schizosaccharomyces pombe and murine Fab1p homologues are phosphatidylinositol 3-phosphate 5-kinasesChaperonin genes on the rise: new divergent classes and intense duplication in human and other vertebrate genomesResearch and progress on ClC‑2 (Review).Functional dissection of lipid and protein kinase signals of PIKfyve reveals the role of PtdIns 3,5-P2 production for endomembrane integrity.Endocytosis and signaling cascades: a close encounter.Acquisition of unprecedented phosphatidylinositol 3,5-bisphosphate rise in hyperosmotically stressed 3T3-L1 adipocytes, mediated by ArPIKfyve-PIKfyve pathway.Phosphatidylinositol 3-kinase and the control of endosome dynamics: new players defined by structural motifs.Signal transduction: stuck with FYVE domains.The phosphatidylinositol 3-phosphate-binding FYVE finger.Phagosome maturation: aging gracefully.Sac3 is an insulin-regulated phosphatidylinositol 3,5-bisphosphate phosphatase: gain in insulin responsiveness through Sac3 down-regulation in adipocytesPhosphoinositide signaling: new tools and insights.A novel PIKFYVE mutation in fleck corneal dystrophyPtdIns5P: news and views of its appearance, disappearance and deeds.Plentiful PtdIns5P from scanty PtdIns(3,5)P2 or from ample PtdIns? PIKfyve-dependent models: Evidence and speculation (response to: DOI 10.1002/bies.201300012).APP controls the formation of PI(3,5)P(2) vesicles through its binding of the PIKfyve complexCritical roles of type III phosphatidylinositol phosphate kinase in murine embryonic visceral endoderm and adult intestine.Phosphoinositides in insulin action on GLUT4 dynamics: not just PtdIns(3,4,5)P3.
P2860
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P2860
Cloning, characterization, and expression of a novel Zn2+-binding FYVE finger-containing phosphoinositide kinase in insulin-sensitive cells
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Cloning, characterization, and ...... ase in insulin-sensitive cells
@ast
Cloning, characterization, and ...... ase in insulin-sensitive cells
@en
Cloning, characterization, and ...... ase in insulin-sensitive cells
@nl
type
label
Cloning, characterization, and ...... ase in insulin-sensitive cells
@ast
Cloning, characterization, and ...... ase in insulin-sensitive cells
@en
Cloning, characterization, and ...... ase in insulin-sensitive cells
@nl
prefLabel
Cloning, characterization, and ...... ase in insulin-sensitive cells
@ast
Cloning, characterization, and ...... ase in insulin-sensitive cells
@en
Cloning, characterization, and ...... ase in insulin-sensitive cells
@nl
P2093
P2860
P3181
P356
P1476
Cloning, characterization, and ...... ase in insulin-sensitive cells
@en
P2093
P2860
P304
P3181
P356
10.1128/MCB.19.1.623
P407
P577
1999-01-01T00:00:00Z