Centrally active modulators of glutamate receptors facilitate the induction of long-term potentiation in vivo
about
Cyclothiazide potently inhibits gamma-aminobutyric acid type A receptors in addition to enhancing glutamate responsesAmpakines cause sustained increases in brain-derived neurotrophic factor signaling at excitatory synapses without changes in AMPA receptor subunit expression7-Chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine S,S-dioxide: a partial modulator of AMPA receptor desensitization devoid of neurotoxicityFragile X syndrome and targeted treatment trials.Structural and Functional Analysis of Two New Positive Allosteric Modulators of GluA2 Desensitization and DeactivationGlutamate receptor ion channels: structure, regulation, and functionMolecular targets for treating cognitive dysfunction in schizophrenia.Effects of D-cycloserine, a positive modulator of N-methyl-D-aspartate receptors, and ST 587, a putative alpha-1 adrenergic agonist, individually and in combination, on the non-delayed and delayed foraging behaviour of rats assessed in the radial arMember of the Ampakine class of memory enhancers prolongs the single channel open time of reconstituted AMPA receptors.Age-Dependent Modifications of AMPA Receptor Subunit Expression Levels and Related Cognitive Effects in 3xTg-AD Mice.The NMDA receptor as a target for cognitive enhancementEnhanced AMPA receptor function promotes cerebellar long-term depression rather than potentiation.Pharmacological characterization of DM232 (unifiram) and DM235 (sunifiram), new potent cognition enhancers.A placebo-controlled add-on trial of the Ampakine, CX516, for cognitive deficits in schizophrenia.GAP-43 is essential for the neurotrophic effects of BDNF and positive AMPA receptor modulator S18986.New life in an old idea: the synaptic plasticity and memory hypothesis revisited.Restoration of long-term potentiation in middle-aged hippocampus after induction of brain-derived neurotrophic factorThe likelihood of cognitive enhancementMutations in ionotropic AMPA receptor 3 alter channel properties and are associated with moderate cognitive impairment in humans.Chronic Ampakine Treatments Stimulate Dendritic Growth and Promote Learning in Middle-Aged RatsThe substrates of memory: defects, treatments, and enhancement.The role of AMPA receptor modulation in the treatment of neuropsychiatric diseasesPost-anesthesia AMPA receptor potentiation prevents anesthesia-induced learning and synaptic deficits.Human cognitive ability is influenced by genetic variation in components of postsynaptic signalling complexes assembled by NMDA receptors and MAGUK proteins.Differences between synaptic plasticity thresholds result in new timing rules for maximizing long-term potentiation.Radiosynthesis of carbon-11 and fluorine-18 labelled radiotracers to image the ionotropic and metabotropic glutamate receptors.Ampakine CX717 potentiates intermittent hypoxia-induced hypoglossal long-term facilitation.Increasing acetylcholine levels in the hippocampus or entorhinal cortex reverses the impairing effects of septal GABA receptor activation on spontaneous alternationFunctional insight into development of positive allosteric modulators of AMPA receptors.Mechanism based approaches for rescuing and enhancing cognition.Interactions of 2,3-benzodiazepines and cyclothiazide at AMPA receptors: patch clamp recordings in cultured neurones and area CA1 in hippocampal slices.The AMPA receptor potentiator LY404187 increases cerebral glucose utilization and c-fos expression in the rat.Facilitation of glutamate receptors reverses an age-associated memory impairment in rats.Pharmacological Modulation of AMPAR Rescues Intellectual Disability-Like Phenotype in Tm4sf2-/y Mice.Acute sleep deprivation: the effects of the AMPAKINE compound CX717 on human cognitive performance, alertness and recovery sleep.Working memory structure and intellectual disability.Prolonged ampakine exposure prunes dendritic spines and increases presynaptic release probability for enhanced long-term potentiation in the hippocampus.
P2860
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P2860
Centrally active modulators of glutamate receptors facilitate the induction of long-term potentiation in vivo
description
1994 nî lūn-bûn
@nan
1994 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Centrally active modulators of ...... long-term potentiation in vivo
@ast
Centrally active modulators of ...... long-term potentiation in vivo
@en
Centrally active modulators of ...... long-term potentiation in vivo
@nl
type
label
Centrally active modulators of ...... long-term potentiation in vivo
@ast
Centrally active modulators of ...... long-term potentiation in vivo
@en
Centrally active modulators of ...... long-term potentiation in vivo
@nl
prefLabel
Centrally active modulators of ...... long-term potentiation in vivo
@ast
Centrally active modulators of ...... long-term potentiation in vivo
@en
Centrally active modulators of ...... long-term potentiation in vivo
@nl
P2093
P2860
P356
P1476
Centrally active modulators of ...... long-term potentiation in vivo
@en
P2093
S Stone-Elander
P2860
P304
P356
10.1073/PNAS.91.23.11158
P407
P577
1994-11-08T00:00:00Z