Growth control of lung cancer by interruption of 5-lipoxygenase-mediated growth factor signaling
about
Polyunsaturated fatty acid metabolism in prostate cancer5-Lipoxygenase and leukotriene B(4) receptor are expressed in human pancreatic cancers but not in pancreatic ducts in normal tissueControl of the growth of human breast cancer cells in culture by manipulation of arachidonate metabolismExpression of 5-lipoxygenase in pulmonary artery endothelial cellsInhibition of peroxisome-proliferator-activated receptor (PPAR)alpha by MK886Methyl jasmonate: putative mechanisms of action on cancer cells cycle, metabolism, and apoptosisRole of LTB₄ in the pathogenesis of elastase-induced murine pulmonary emphysemaRestoration of leukotriene B(4)-12-hydroxydehydrogenase/15- oxo-prostaglandin 13-reductase (LTBDH/PGR) expression inhibits lung cancer growth in vitro and in vivo.Inhalation of an ethanol-based zileuton formulation provides a reduction of pulmonary adenomas in the A/J mouse model.Intracellular compartmentalization of leukotriene biosynthesis.Targeting the eicosanoid pathway in non-small-cell lung cancer.Potential use of lipoxygenase inhibitors for cancer chemoprevention.Genetic variants in the metabolism of omega-6 and omega-3 fatty acids: their role in the determination of nutritional requirements and chronic disease risk.The role of cyclooxygenase and lipoxygenase in cancer chemoprevention.Recent molecular advances in the approach to early lung cancer detection and intervention.Fatty acid oxidation and signaling in apoptosis.Chemoprevention of colon and small intestinal tumorigenesis in APC(Min/+) mice by licofelone, a novel dual 5-LOX/COX inhibitor: potential implications for human colon cancer prevention.The eicosanoid cascade: possible role in gliomas and meningiomas.Nordihydroguaiaretic Acid Extends the Lifespan of Drosophila and Mice, Increases Mortality-Related Tumors and Hemorrhagic Diathesis, and Alters Energy Homeostasis in Mice.Structure and ligand based drug design strategies in the development of novel 5- LOX inhibitors.Inhibition of IGF-1R and lipoxygenase by nordihydroguaiaretic acid (NDGA) analogs.Lipoxygenase and Cyclooxygenase Pathways and Colorectal Cancer PreventionWhat are cyclooxygenases and lipoxygenases doing in the driver's seat of carcinogenesis?Therapeutic resistance in lung cancer.Mechanisms of nordihydroguaiaretic acid-induced growth inhibition and apoptosis in human cancer cellsChemoprevention of lung cancer: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelinesCytosolic phospholipase A2 (cPLA2) IVA as a potential signature molecule in cigarette smoke condensate induced pathologies in alveolar epithelial lineages.Nordihydroguaiaretic acid inhibits transforming growth factor beta type 1 receptor activity and downstream signaling.Redox-active antioxidant modulation of lipid signaling in vascular endothelial cells: vitamin C induces activation of phospholipase D through phospholipase A2, lipoxygenase, and cyclooxygenase.Levels of prostaglandin E metabolite and leukotriene E(4) are increased in the urine of smokers: evidence that celecoxib shunts arachidonic acid into the 5-lipoxygenase pathway.Review paper: the role of inflammation in mouse pulmonary neoplasia.Synthesis, characterization, and anti-melanoma activity of tetra-O-substituted analogs of nordihydroguaiaretic acid.Paradoxical cellular effects and biological role of the multifaceted compound nordihydroguaiaretic acid.The 5-lipoxygenase-activating protein (FLAP) inhibitor, MK886, induces apoptosis independently of FLAP.Serum 5-LOX: a progressive protein marker for breast cancer and new approach for therapeutic target.Nanovesicular carrier-based formulation for skin cancer targeting: evaluation of cytotoxicity, intracellular uptake, and preclinical anticancer activity.Therapeutic applications of the versatile fatty acid mimetic WY14643.mTORC1 is a target of nordihydroguaiaretic acid to prevent breast tumor growth in vitro and in vivo.Inhibitory effect of nordihydroguaiaretic acid on β-catenin/Tcf signalling in β-catenin-activated cells.Inhibition of 5-lipoxygenase pathway suppresses the growth of bladder cancer cells.
P2860
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P2860
Growth control of lung cancer by interruption of 5-lipoxygenase-mediated growth factor signaling
description
1996 nî lūn-bûn
@nan
1996 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Growth control of lung cancer ...... diated growth factor signaling
@ast
Growth control of lung cancer ...... diated growth factor signaling
@en
Growth control of lung cancer ...... diated growth factor signaling
@nl
type
label
Growth control of lung cancer ...... diated growth factor signaling
@ast
Growth control of lung cancer ...... diated growth factor signaling
@en
Growth control of lung cancer ...... diated growth factor signaling
@nl
prefLabel
Growth control of lung cancer ...... diated growth factor signaling
@ast
Growth control of lung cancer ...... diated growth factor signaling
@en
Growth control of lung cancer ...... diated growth factor signaling
@nl
P2093
P2860
P3181
P356
P1476
Growth control of lung cancer ...... diated growth factor signaling
@en
P2093
A M Treston
A Martínez
J L Mulshine
P2860
P304
P3181
P356
10.1172/JCI118480
P407
P577
1996-02-01T00:00:00Z