Tight association of GRB2 with receptor protein-tyrosine phosphatase alpha is mediated by the SH2 and C-terminal SH3 domains
about
A phosphotyrosine displacement mechanism for activation of Src by PTPalphaMitotic activation of protein-tyrosine phosphatase alpha and regulation of its Src-mediated transforming activity by its sites of protein kinase C phosphorylationActivation of Src and transformation by an RPTPα splice mutant found in human tumoursWiskott-Aldrich syndrome protein is associated with the adapter protein Grb2 and the epidermal growth factor receptor in living cellsThe Croonian Lecture 1997. The phosphorylation of proteins on tyrosine: its role in cell growth and diseaseDimerization of receptor protein-tyrosine phosphatase alpha in living cellsDesign, generation, and testing of mammalian expression modules that tag membrane proteinsComparative study of protein tyrosine phosphatase-epsilon isoforms: membrane localization confers specificity in cellular signallingMultiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation eventsSUMOylation of Grb2 enhances the ERK activity by increasing its binding with Sos1.Persistent activation of mitogen-activated protein kinases p42 and p44 and ets-2 phosphorylation in response to colony-stimulating factor 1/c-fms signalingReceptor-like protein tyrosine phosphatase alpha homodimerizes on the cell surface.Striatal-enriched protein tyrosine phosphatase regulates the PTPα/Fyn signaling pathwayAdaptor protein GRB2 promotes Src tyrosine kinase activation and podosomal organization by protein-tyrosine phosphatase ϵ in osteoclasts.Receptor type protein tyrosine phosphatases (RPTPs) - roles in signal transduction and human disease.RPTPalpha is essential for NCAM-mediated p59fyn activation and neurite elongation.NCAM induces CaMKIIalpha-mediated RPTPalpha phosphorylation to enhance its catalytic activity and neurite outgrowth.Extracellular domain dependence of PTPalpha transforming activityGrb2 promotes integrin-induced focal adhesion kinase (FAK) autophosphorylation and directs the phosphorylation of protein tyrosine phosphatase α by the Src-FAK kinase complex.Serine dephosphorylation of receptor protein tyrosine phosphatase alpha in mitosis induces Src binding and activation.
P2860
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P2860
Tight association of GRB2 with receptor protein-tyrosine phosphatase alpha is mediated by the SH2 and C-terminal SH3 domains
description
1996 nî lūn-bûn
@nan
1996 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Tight association of GRB2 with ...... SH2 and C-terminal SH3 domains
@ast
Tight association of GRB2 with ...... SH2 and C-terminal SH3 domains
@en
Tight association of GRB2 with ...... SH2 and C-terminal SH3 domains
@nl
type
label
Tight association of GRB2 with ...... SH2 and C-terminal SH3 domains
@ast
Tight association of GRB2 with ...... SH2 and C-terminal SH3 domains
@en
Tight association of GRB2 with ...... SH2 and C-terminal SH3 domains
@nl
prefLabel
Tight association of GRB2 with ...... SH2 and C-terminal SH3 domains
@ast
Tight association of GRB2 with ...... SH2 and C-terminal SH3 domains
@en
Tight association of GRB2 with ...... SH2 and C-terminal SH3 domains
@nl
P2860
P1433
P1476
Tight association of GRB2 with ...... SH2 and C-terminal SH3 domains
@en
P2093
J den Hertog
P2860
P304
P407
P577
1996-06-17T00:00:00Z