Ketoconazole blocks adrenal steroidogenesis by inhibiting cytochrome P450-dependent enzymes
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Systemic therapy of Cushing's syndromeOverview of medically important antifungal azole derivativesHormonal impact of the 17alpha-hydroxylase/C(17,20)-lyase inhibitor abiraterone acetate (CB7630) in patients with prostate cancerTherapeutic Rationales, Progresses, Failures, and Future Directions for Advanced Prostate CancerThe Treatment of Cushing's Disease.Role of "old" pharmacological agents in the treatment of Cushing's syndromeEvidence for digenic inheritance in some cases of Antley-Bixler syndrome?Summary of information on human CYP enzymes: human P450 metabolism data.Selective inhibition of steroidogenic enzymes by ketoconazole in rat ovary cellsDifferential metabolism of 25-hydroxyvitamin D3 by cultured synovial fluid macrophages and fibroblast-like cells from patients with arthritisUpdate on medical treatment for Cushing's disease.Ketoconazole binds to glucocorticoid receptors and exhibits glucocorticoid antagonist activity in cultured cells.Prenatal exposure to antifungal medication may change anogenital distance in male offspring: a preliminary studyVitamin D metabolism and action in the prostate: implications for health and disease.Preoperative ketoconazole therapy for adrenocortical carcinomaThe effect of ketoconazole on post-burn inflammation, hypermetabolism and clinical outcomes.Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors.Effects of single and multiple doses of ketoconazole on adrenal function in normal subjects.Tissue-specific regulation of pregnane X receptor in cancer development and therapy.CYP17 blockade by abiraterone: further evidence for frequent continued hormone-dependence in castration-resistant prostate cancer.Abiraterone acetate: a promising drug for the treatment of castration-resistant prostate cancer.Feline hyperadrenocorticism--where are we now?Impact of fluconazole prophylaxis on cortisol levels in critically ill surgical patientsComparison of fluconazole and SDZ89-485 for therapy of experimental murine coccidioidomycosis.Antifungal therapy: from amphotericin B to present.Analysis of cytochrome P450 CYP119 ligand-dependent conformational dynamics by two-dimensional NMR and X-ray crystallography.Adrenal response to corticotropin during therapy with itraconazole.Ketoconazole in experimental vaginal candidosis in ratsCurrent and emerging therapies for advanced adrenocortical carcinoma.Is there a role for fluconazole in the treatment of vulvovaginal candidiasis?Vitamin D3 May Ameliorate the Ketoconazole Induced Adrenal Injury: Histological and Immunohistochemical Studies on Albino Rats.High dose ketoconazole: endocrine and therapeutic effects in postmenopausal breast cancer.Effects of CYP3A4 inhibitors on the pharmacokinetics of maraviroc in healthy volunteersHigh-Throughput Screening of Chemical Effects on Steroidogenesis Using H295R Human Adrenocortical Carcinoma Cells.High-dose itraconazole in the treatment of severe mycoses.Novel functionalized 5-(phenoxymethyl)-1,3-dioxane analogs exhibiting cytochrome P450 inhibition: a patent evaluation WO2015048311 (A1)The effect of prior androgen synthesis inhibition on outcomes of subsequent therapy with docetaxel in patients with metastatic castrate-resistant prostate cancer: results from a retrospective analysis of a randomized phase 3 clinical trial (CALGB 90Pregnane glycosides interfere with steroidogenic enzymes to down-regulate corticosteroid production in human adrenocortical H295R cellsExpression and enzymatic activity of recombinant cytochrome P450 17 alpha-hydroxylase in Escherichia coli.Medical suppression of hypercortisolemia in Cushing's syndrome with particular consideration of etomidate.
P2860
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P2860
Ketoconazole blocks adrenal steroidogenesis by inhibiting cytochrome P450-dependent enzymes
description
1983 nî lūn-bûn
@nan
1983 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1983 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1983年の論文
@ja
1983年学术文章
@wuu
1983年学术文章
@zh-cn
1983年学术文章
@zh-hans
1983年学术文章
@zh-my
1983年学术文章
@zh-sg
1983年學術文章
@yue
name
Ketoconazole blocks adrenal st ...... ochrome P450-dependent enzymes
@ast
Ketoconazole blocks adrenal st ...... ochrome P450-dependent enzymes
@en
Ketoconazole blocks adrenal st ...... ochrome P450-dependent enzymes
@nl
type
label
Ketoconazole blocks adrenal st ...... ochrome P450-dependent enzymes
@ast
Ketoconazole blocks adrenal st ...... ochrome P450-dependent enzymes
@en
Ketoconazole blocks adrenal st ...... ochrome P450-dependent enzymes
@nl
prefLabel
Ketoconazole blocks adrenal st ...... ochrome P450-dependent enzymes
@ast
Ketoconazole blocks adrenal st ...... ochrome P450-dependent enzymes
@en
Ketoconazole blocks adrenal st ...... ochrome P450-dependent enzymes
@nl
P2093
P2860
P3181
P356
P1476
Ketoconazole blocks adrenal st ...... ochrome P450-dependent enzymes
@en
P2093
P2860
P304
P3181
P356
10.1172/JCI110903
P407
P577
1983-05-01T00:00:00Z