Leucine aminopeptidase: bestatin inhibition and a model for enzyme-catalyzed peptide hydrolysis
about
Interactions of Streptomyces griseus aminopeptidase with amino acid reaction products and their implications toward a catalytic mechanismStructural basis for substrate recognition and hydrolysis by mouse carnosinase CN2Synthesis of New (−)-Bestatin-Based Inhibitor Libraries Reveals a Novel Binding Mode in the S1 Pocket of the Essential Malaria M1 MetalloaminopeptidaseBestatin-based chemical biology strategy reveals distinct roles for malaria M1- and M17-family aminopeptidasesBiochemical Properties and Crystal Structure of a -Phenylalanine Aminotransferase from Variovorax paradoxusStructure of tomato wound-induced leucine aminopeptidase sheds light on substrate specificityDifferentiation and identification of the two catalytic metal binding sites in bovine lens leucine aminopeptidase by x-ray crystallographyIdentification of residues critical for activity of the wound-induced leucine aminopeptidase (LAP-A) of tomatoIn vivo imaging of leucine aminopeptidase activity in drug-induced liver injury and liver cancer via a near-infrared fluorescent probe.Novel small molecule nonpeptide aminopeptidase n inhibitors with a cyclic imide skeleton.Cocatalytic zinc motifs in enzyme catalysis.Leucine aminopeptidase: an inducible component of the defense response in Lycopersicon esculentum (tomato).Design, synthesis, and biological evaluation of water-soluble amino acid prodrug conjugates derived from combretastatin, dihydronaphthalene, and benzosuberene-based parent vascular disrupting agentsExpression of virus-encoded proteinases: functional and structural similarities with cellular enzymesThe Activity of a Hexameric M17 Metallo-Aminopeptidase Is Associated With Survival of Mycobacterium tuberculosis.Cysteinyl-glycine in the control of glutathione homeostasis in bovine lenses.Cloning, purification and preliminary crystallographic analysis of the Helicobacter pylori leucyl aminopeptidase-bestatin complex.The thermophilic, homohexameric aminopeptidase of Borrelia burgdorferi is a member of the M29 family of metallopeptidases.Leukotriene A4 hydrolase: a critical role of glutamic acid-296 for the binding of bestatin.Development of bestatin-based activity-based probes for metallo-aminopeptidases.Bestatin inhibits cell growth, cell division, and spore cell differentiation in Dictyostelium discoideum.Aminopeptidases from Plasmodium falciparum, Plasmodium chabaudi chabaudi and Plasmodium berghei.Effect of peptidases on the ability of exogenous and endogenous neurokinins to produce neurokinin 1 receptor internalization in the rat spinal cord.Randomized double-blind placebo-controlled trial of bestatin in patients with resected stage I squamous-cell lung carcinoma.Structural insights into chaperone-activity enhancement by a K354E mutation in tomato acidic leucine aminopeptidase.Combinatorial multicomponent access to natural-products-inspired peptidomimetics: discovery of selective inhibitors of microbial metallo-aminopeptidases.Three-dimensional structural resemblance between leucine aminopeptidase and carboxypeptidase A revealed by graph-theoretical techniques.
P2860
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P2860
Leucine aminopeptidase: bestatin inhibition and a model for enzyme-catalyzed peptide hydrolysis
description
1991 nî lūn-bûn
@nan
1991 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
Leucine aminopeptidase: bestat ...... e-catalyzed peptide hydrolysis
@ast
Leucine aminopeptidase: bestat ...... e-catalyzed peptide hydrolysis
@en
Leucine aminopeptidase: bestat ...... e-catalyzed peptide hydrolysis
@nl
type
label
Leucine aminopeptidase: bestat ...... e-catalyzed peptide hydrolysis
@ast
Leucine aminopeptidase: bestat ...... e-catalyzed peptide hydrolysis
@en
Leucine aminopeptidase: bestat ...... e-catalyzed peptide hydrolysis
@nl
prefLabel
Leucine aminopeptidase: bestat ...... e-catalyzed peptide hydrolysis
@ast
Leucine aminopeptidase: bestat ...... e-catalyzed peptide hydrolysis
@en
Leucine aminopeptidase: bestat ...... e-catalyzed peptide hydrolysis
@nl
P2860
P356
P1476
Leucine aminopeptidase: bestat ...... e-catalyzed peptide hydrolysis
@en
P2093
W N Lipscomb
P2860
P304
P356
10.1073/PNAS.88.16.6916
P407
P577
1991-08-01T00:00:00Z