Eps8, a substrate for the epidermal growth factor receptor kinase, enhances EGF-dependent mitogenic signals
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The eps8 family of proteins links growth factor stimulation to actin reorganization generating functional redundancy in the Ras/Rac pathwayMNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substratesCell fate-specific regulation of EGF receptor trafficking during Caenorhabditis elegans vulval developmentEpidermal growth factor and betacellulin mediate signal transduction through co-expressed ErbB2 and ErbB3 receptorsInteraction of the PA2G4 (EBP1) protein with ErbB-3 and regulation of this binding by heregulinWiskott-Aldrich syndrome protein physically associates with Nck through Src homology 3 domainsConstitutive phosphorylation of eps8 in tumor cell lines: relevance to malignant transformationAn effector region in Eps8 is responsible for the activation of the Rac-specific GEF activity of Sos-1 and for the proper localization of the Rac-based actin-polymerizing machineRegulation of actin cytoskeleton architecture by Eps8 and Abi1.Eps8 regulates hair bundle length and functional maturation of mammalian auditory hair cells.Eps8 regulates axonal filopodia in hippocampal neurons in response to brain-derived neurotrophic factor (BDNF)Identification and dissection of four major QTL affecting milk fat content in the German Holstein-Friesian populationNovel binding partners and differentially regulated phosphorylation sites clarify Eps8 as a multi-functional adaptorIdentification of nucleolin as new ErbB receptors- interacting proteinSCFFbxw5 mediates transient degradation of actin remodeller Eps8 to allow proper mitotic progressionGrowth factor-induced tyrosine phosphorylation of Hrs, a novel 115-kilodalton protein with a structurally conserved putative zinc finger domainControlled dimerization of ErbB receptors provides evidence for differential signaling by homo- and heterodimersA graph kernel approach for alignment-free domain-peptide interaction prediction with an application to human SH3 domainsMechanisms through which Sos-1 coordinates the activation of Ras and Rac.Erk regulation of actin capping and bundling by Eps8 promotes cortex tension and leader bleb-based migration.The actin associated protein palladin in smooth muscle and in the development of diseases of the cardiovasculature and in cancer.Eps8 is recruited to lysosomes and subjected to chaperone-mediated autophagy in cancer cellsβ-Adrenergic receptor-mediated transactivation of epidermal growth factor receptor decreases cardiomyocyte apoptosis through differential subcellular activation of ERK1/2 and Akt.Disruption of blastomeric F-actin: a potential early biomarker of developmental toxicity in zebrafish.Gene expression profiling defined pathways correlated with fibroblast cell proliferation induced by Opisthorchis viverrini excretory/secretory product.EPS8 upregulates FOXM1 expression, enhancing cell growth and motilityP66shc and its downstream Eps8 and Rac1 proteins are upregulated in esophageal cancers.c-Jun N-terminal kinase 2 (JNK2) enhances cell migration through epidermal growth factor substrate 8 (EPS8).Cell type-specific expression of Eps8 in the mouse hippocampus.Functional determinants of ras interference 1 mutants required for their inhbitory activity on endocytosis.Ezrin regulates microvillus morphogenesis by promoting distinct activities of Eps8 proteins.Postsynaptic enrichment of Eps8 at dendritic shaft synapses of unipolar brush cells in rat cerebellum.Genome-wide associations for milk production and somatic cell score in Holstein-Friesian cattle in Ireland.Eps8 protein facilitates phagocytosis by increasing TLR4-MyD88 protein interaction in lipopolysaccharide-stimulated macrophages.Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: roles of integrin aggregation and occupancy of receptorsPhosphoinositide 3-kinase activates Rac by entering in a complex with Eps8, Abi1, and Sos-1.Np95 is regulated by E1A during mitotic reactivation of terminally differentiated cells and is essential for S phase entryComparative genomic hybridization and histological variation in primitive neuroectodermal tumoursAn epidermal growth factor receptor/ret chimera generates mitogenic and transforming signals: evidence for a ret-specific signaling pathway.Chronic exposure to chewing tobacco selects for overexpression of stearoyl-CoA desaturase in normal oral keratinocytes.
P2860
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P2860
Eps8, a substrate for the epidermal growth factor receptor kinase, enhances EGF-dependent mitogenic signals
description
1993 nî lūn-bûn
@nan
1993 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
name
Eps8, a substrate for the epid ...... GF-dependent mitogenic signals
@ast
Eps8, a substrate for the epid ...... GF-dependent mitogenic signals
@en
Eps8, a substrate for the epid ...... GF-dependent mitogenic signals
@nl
type
label
Eps8, a substrate for the epid ...... GF-dependent mitogenic signals
@ast
Eps8, a substrate for the epid ...... GF-dependent mitogenic signals
@en
Eps8, a substrate for the epid ...... GF-dependent mitogenic signals
@nl
prefLabel
Eps8, a substrate for the epid ...... GF-dependent mitogenic signals
@ast
Eps8, a substrate for the epid ...... GF-dependent mitogenic signals
@en
Eps8, a substrate for the epid ...... GF-dependent mitogenic signals
@nl
P2093
P2860
P3181
P1433
P1476
Eps8, a substrate for the epid ...... GF-dependent mitogenic signals
@en
P2093
Castagnino P
Di Fiore PP
Minichiello L
P2860
P304
P3181
P356
10.1002/J.1460-2075.1993.TB06058.X
P407
P577
1993-10-01T00:00:00Z