CP110 suppresses primary cilia formation through its interaction with CEP290, a protein deficient in human ciliary disease
about
FAM161A, associated with retinitis pigmentosa, is a component of the cilia-basal body complex and interacts with proteins involved in ciliopathiesTULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary ciliaStabilization of cartwheel-less centrioles for duplication requires CEP295-mediated centriole-to-centrosome conversionOfd1, a human disease gene, regulates the length and distal structure of centriolesThe spinocerebellar ataxia-associated gene Tau tubulin kinase 2 controls the initiation of ciliogenesisUbiquitin-proteasome system controls ciliogenesis at the initial step of axoneme extensionCombining Cep290 and Mkks ciliopathy alleles in mice rescues sensory defects and restores ciliogenesisCentriole distal appendages promote membrane docking, leading to cilia initiationCep76, a centrosomal protein that specifically restrains centriole reduplicationThe novel centriolar satellite protein SSX2IP targets Cep290 to the ciliary transition zoneEarly steps in primary cilium assembly require EHD1/EHD3-dependent ciliary vesicle formationThe CP110-interacting proteins Talpid3 and Cep290 play overlapping and distinct roles in cilia assemblyOFD1 is mutated in X-linked Joubert syndrome and interacts with LCA5-encoded lebercilinA SNX10/V-ATPase pathway regulates ciliogenesis in vitro and in vivomiR-129-3p controls cilia assembly by regulating CP110 and actin dynamicsCEP162 is an axoneme-recognition protein promoting ciliary transition zone assembly at the cilia baseDisruption of CEP290 microtubule/membrane-binding domains causes retinal degenerationThe role of primary cilia in neuronal functionThe primary cilium as a cellular signaling center: lessons from diseaseCellular Mechanisms of Ciliary Length ControlCurrent topics of functional links between primary cilia and cell cycleMolecular complexes that direct rhodopsin transport to primary ciliaInositol polyphosphate 5-phosphatases; new players in the regulation of cilia and ciliopathiesRPGRIP1 and cone-rod dystrophy in dogsScrutinizing ciliopathies by unraveling ciliary interaction networksCEP290 alleles in mice disrupt tissue-specific cilia biogenesis and recapitulate features of syndromic ciliopathiesInvestigating embryonic expression patterns and evolution of AHI1 and CEP290 genes, implicated in Joubert syndromeCDK2 Inhibition Causes Anaphase Catastrophe in Lung Cancer through the Centrosomal Protein CP110Trafficking to the ciliary membrane: how to get across the periciliary diffusion barrier?The Arf GAP ASAP1 provides a platform to regulate Arf4- and Rab11-Rab8-mediated ciliary receptor targeting.CP110 and its network of partners coordinately regulate cilia assembly.C2cd3 is critical for centriolar distal appendage assembly and ciliary vesicle docking in mammals.The Cilium: Cellular Antenna and Central Processing UnitPathogenic NPHP5 mutations impair protein interaction with Cep290, a prerequisite for ciliogenesisNephrocystin proteins NPHP5 and Cep290 regulate BBSome integrity, ciliary trafficking and cargo deliveryCentriolar satellites: key mediators of centrosome functionsInteraction of retinitis pigmentosa GTPase regulator (RPGR) with RAB8A GTPase: implications for cilia dysfunction and photoreceptor degenerationPrimary cilia control hedgehog signaling during muscle differentiation and are deregulated in rhabdomyosarcomaRetinal degeneration and failure of photoreceptor outer segment formation in mice with targeted deletion of the Joubert syndrome gene, Ahi1Ahi1, whose human ortholog is mutated in Joubert syndrome, is required for Rab8a localization, ciliogenesis and vesicle trafficking
P2860
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P2860
CP110 suppresses primary cilia formation through its interaction with CEP290, a protein deficient in human ciliary disease
description
2008 nî lūn-bûn
@nan
2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
CP110 suppresses primary cilia ...... cient in human ciliary disease
@ast
CP110 suppresses primary cilia ...... cient in human ciliary disease
@en
CP110 suppresses primary cilia ...... cient in human ciliary disease
@nl
type
label
CP110 suppresses primary cilia ...... cient in human ciliary disease
@ast
CP110 suppresses primary cilia ...... cient in human ciliary disease
@en
CP110 suppresses primary cilia ...... cient in human ciliary disease
@nl
prefLabel
CP110 suppresses primary cilia ...... cient in human ciliary disease
@ast
CP110 suppresses primary cilia ...... cient in human ciliary disease
@en
CP110 suppresses primary cilia ...... cient in human ciliary disease
@nl
P2093
P2860
P50
P3181
P1433
P1476
CP110 suppresses primary cilia ...... ient in human ciliary disease.
@en
P2093
Brian David Dynlacht
Carine Bossard
Johan Peränen
P2860
P304
P3181
P356
10.1016/J.DEVCEL.2008.07.004
P407
P577
2008-08-01T00:00:00Z