PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53 - Test2 - elhamkhani - TriplyDB

PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53

PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53

http://www.wikidata.org/entity/Q24594648

about

Structural analysis of the KANSL1/WDR5/KANSL2 complex reveals that WDR5 is required for efficient assembly and chromatin targeting of the NSL complex Multiple facets of p53 in senescence induction and maintenance The functional diversity of protein lysine methylation MOF-associated complexes ensure stem cell identity and Xist repression.Mutant TP53 posttranslational modifications: challenges and opportunities.Identification of hidden relationships from the coupling of hydrophobic cluster analysis and domain architecture information.An acetyl-methyl switch drives a conformational change in p53.Structural plasticity of methyllysine recognition by the tandem tudor domain of 53BP1 A nonsense mutation in the DNA repair factor Hebo causes mild bone marrow failure and microcephaly.Expression of PHF20 protein contributes to good prognosis of NSCLC and is associated with Bax expression.SCF(Fbxo22)-KDM4A targets methylated p53 for degradation and regulates senescence.G9a-mediated methylation of ERα links the PHF20/MOF histone acetyltransferase complex to hormonal gene expression.A Small Protein Associated with Fungal Energy Metabolism Affects the Virulence of Cryptococcus neoformans in Mammals.PHF20 Readers Link Methylation of Histone H3K4 and p53 with H4K16 Acetylation.PHF20 regulates NF-κB signalling by disrupting recruitment of PP2A to p65 Methyllysine reader plant homeodomain (PHD) finger protein 20-like 1 (PHF20L1) antagonizes DNA (cytosine-5) methyltransferase 1 (DNMT1) proteasomal degradation.Sprint-interval but not continuous exercise increases PGC-1α protein content and p53 phosphorylation in nuclear fractions of human skeletal muscle.Emerging roles for chromatin as a signal integration and storage platform.Tudor: a versatile family of histone methylation 'readers'.Post-translational control of transcription factors: methylation ranks highly.Biological function and regulation of histone and non-histone lysine methylation in response to DNA damage.Beyond histones - the expanding roles of protein lysine methylation.PHF20 positively regulates osteoblast differentiation via increasing the expression and activation of Runx2 with enrichment of H3K4me3.Identification of genes and pathways potentially related to PHF20 by gene expression profile analysis of glioblastoma U87 cell line TP53 Regulates Metabolic Genes Regulation of TP53 Activity through Association with Co-factors The guardian of the genome p53 regulates exercise-induced mitochondrial plasticity beyond organelle biogenesis.A molecular engineering toolbox for the structural biologist.Cold-water immersion following sprint interval training does not alter endurance signaling pathways or training adaptations in human skeletal muscle.Identification of protein lysine methylation readers with a yeast three-hybrid approach.PHF20 binds TP53 dimethylated on K370 and K382 Delineating Crosstalk Mechanisms of the Ubiquitin Proteasome System That Regulate Apoptosis.Altered expression of tumor suppressor PHF20 in myeloproliferative neoplasms.Cancer cell metabolism as new targets for novel designed therapies

P2860

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P2860

PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53

http://www.wikidata.org/entity/Q24594648

description

2012 nî lūn-bûn

@nan

2012 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2012年の論文

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2012年論文

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2012年論文

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2012年論文

@zh-hk

2012年論文

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2012年論文

@zh-tw

2012年论文

@wuu

name

PHF20 is an effector protein o ...... t stabilizes and activates p53

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PHF20 is an effector protein o ...... t stabilizes and activates p53

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PHF20 is an effector protein o ...... t stabilizes and activates p53

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PHF20 is an effector protein o ...... t stabilizes and activates p53

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PHF20 is an effector protein o ...... t stabilizes and activates p53

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PHF20 is an effector protein o ...... t stabilizes and activates p53

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prefLabel

PHF20 is an effector protein o ...... t stabilizes and activates p53

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PHF20 is an effector protein o ...... t stabilizes and activates p53

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Nature Structural & Molecular Biology

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PHF20 is an effector protein o ...... t stabilizes and activates p53

@en

P2093

Aimee I Badeaux

http://www.w3.org/2001/XMLSchema#string

Donghwa Kim

http://www.w3.org/2001/XMLSchema#string

Fei Yan

http://www.w3.org/2001/XMLSchema#string

Gaofeng Cui

http://www.w3.org/2001/XMLSchema#string

Georges Mer

http://www.w3.org/2001/XMLSchema#string

James R Thompson

http://www.w3.org/2001/XMLSchema#string

Jin Q Cheng

http://www.w3.org/2001/XMLSchema#string

Joseph Lee

http://www.w3.org/2001/XMLSchema#string

Maria Victoria Botuyan

http://www.w3.org/2001/XMLSchema#string

Mark T Bedford

http://www.w3.org/2001/XMLSchema#string

P2860

Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure

Subunit composition and substrate specificity of a MOF-containing histone acetyltransferase distinct from the male-specific lethal (MSL) complex

Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases

p53 is regulated by the lysine demethylase LSD1

Tudor, MBT and chromo domains gauge the degree of lysine methylation

Specificity and mechanism of the histone methyltransferase Pr-Set7.

Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF

Repression of p53 activity by Smyd2-mediated methylation

Modulation of p53 function by SET8-mediated methylation at lysine 382

Structural and functional analysis of SET8, a histone H4 Lys-20 methyltransferase

P2888

P304

916-24

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scholarly article

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3761441

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10.1038/NSMB.2353

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9

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19

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2012-09-01T00:00:00Z

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230619365

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1007776380

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22864287

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structural biology

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3454513

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