Serpins flex their muscle: I. Putting the clamps on proteolysis in diverse biological systems
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Serpins flex their muscle: II. Structural insights into target peptidase recognition, polymerization, and transport functions93-kDa twin-domain serine protease inhibitor (Serpin) has a regulatory function on the beetle Toll proteolytic signaling cascadeCrystal structure of native Anopheles gambiae serpin-2, a negative regulator of melanization in mosquitoesSerine protease MP2 activates prophenoloxidase in the melanization immune response of Drosophila melanogasterSplicing variants of SERPINA1 gene in ovine milk: characterization of cDNA and identification of polymorphismsTranscriptome profiling of ontogeny in the acridid grasshopper Chorthippus biguttulus.Human subtilase SKI-1/S1P is a master regulator of the HCV Lifecycle and a potential host cell target for developing indirect-acting antiviral agentsSERPINB3 is associated with TGF-β1 and cytoplasmic β-catenin expression in hepatocellular carcinomas with poor prognosis.Protease Inhibitors in Tick Saliva: The Role of Serpins and Cystatins in Tick-host-Pathogen Interaction.A blood meal-induced Ixodes scapularis tick saliva serpin inhibits trypsin and thrombin, and interferes with platelet aggregation and blood clotting.Comparison of two neurotrophic serpins reveals a small fragment with cell survival activity.Retention of thrombin inhibitory activity by recombinant serpins expressed as integral membrane proteins tethered to the surface of mammalian cells.Characterization of a novel serine protease inhibitor gene from a marine metagenome.A genome-wide RNAi screen identifies potential drug targets in a C. elegans model of α1-antitrypsin deficiency.Genome-wide identification and immune response analysis of serine protease inhibitor genes in the silkworm, Bombyx moriSerpin protease inhibitors in plant biology.Novel scabies mite serpins inhibit the three pathways of the human complement system.Serpins in rice: protein sequence analysis, phylogeny and gene expression during development.Viral cross-class serpin inhibits vascular inflammation and T lymphocyte fratricide; a study in rodent models in vivo and human cell lines in vitro.Heparin is a major activator of the anticoagulant serpin, protein Z-dependent protease inhibitor.Miropin, a novel bacterial serpin from the periodontopathogen Tannerella forsythia, inhibits a broad range of proteases by using different peptide bonds within the reactive center loop.Fusion of the C-terminal triskaidecapeptide of hirudin variant 3 to alpha1-proteinase inhibitor M358R increases the serpin-mediated rate of thrombin inhibition.Using C. elegans to identify the protease targets of serpins in vivoThe aggregation-prone intracellular serpin SRP-2 fails to transit the ER in Caenorhabditis elegans.ANISERP: a new serpin from the parasite Anisakis simplex.A versatile monoclonal antibody specific to human SERPINB5A Novel Serpin Regulatory Mechanism: SerpinB9 IS REVERSIBLY INHIBITED BY VICINAL DISULFIDE BOND FORMATION IN THE REACTIVE CENTER LOOPHuman SERPINB12 Is an Abundant Intracellular Serpin Expressed in Most Surface and Glandular Epithelia.The effects of PEDF on cancer biology: mechanisms of action and therapeutic potentialThe circadian Clock gene regulates acrosin activity of sperm through serine protease inhibitor A3KKinetic intermediates en route to the final serpin-protease complex: studies of complexes of α1-protease inhibitor with trypsinPhage display of the serpin alpha-1 proteinase inhibitor randomized at consecutive residues in the reactive centre loop and biopanned with or without thrombin.Identification of immunity-related genes in Ostrinia furnacalis against entomopathogenic fungi by RNA-seq analysis.Identification and function of proteolysis regulators in seminal fluid.Serine protease SP105 activates prophenoloxidase in Asian corn borer melanization, and is regulated by serpin-3.The structure and function of mammalian membrane-attack complex/perforin-like proteins.Hepatic fibrosis and carcinogenesis in α1-antitrypsin deficiency: a prototype for chronic tissue damage in gain-of-function disorders.Viral serpin therapeutics from concept to clinic.Serine protease inhibitors of parasitic helminths.Novel treatment strategies for liver disease due to α1-antitrypsin deficiency.
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P2860
Serpins flex their muscle: I. Putting the clamps on proteolysis in diverse biological systems
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2010 nî lūn-bûn
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2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
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name
Serpins flex their muscle: I. ...... in diverse biological systems
@ast
Serpins flex their muscle: I. ...... in diverse biological systems
@en
Serpins flex their muscle: I. ...... in diverse biological systems
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type
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Serpins flex their muscle: I. ...... in diverse biological systems
@ast
Serpins flex their muscle: I. ...... in diverse biological systems
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Serpins flex their muscle: I. ...... in diverse biological systems
@nl
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Serpins flex their muscle: I. ...... in diverse biological systems
@ast
Serpins flex their muscle: I. ...... in diverse biological systems
@en
Serpins flex their muscle: I. ...... in diverse biological systems
@nl
P2093
P2860
P356
P1476
Serpins flex their muscle: I. ...... in diverse biological systems
@en
P2093
Cliff J Luke
Dion Kaiserman
Gary A Silverman
James A Huntington
Jean-Marc Reichhart
Stephen C Pak
Stephen P Bottomley
P2860
P304
P356
10.1074/JBC.R110.112771
P407
P577
2010-08-06T00:00:00Z