Diels-Alder cycloaddition for fluorophore targeting to specific proteins inside living cells - Test2 - elhamkhani - TriplyDB

Diels-Alder cycloaddition for fluorophore targeting to specific proteins inside living cells

Diels-Alder cycloaddition for fluorophore targeting to specific proteins inside living cells

http://www.wikidata.org/entity/Q24599345

about

Click chemistry in complex mixtures: bioorthogonal bioconjugation Site-specific functionalization of proteins and their applications to therapeutic antibodies Specific and quantitative labeling of biomolecules using click chemistry Bioorthogonal chemistry: strategies and recent developments Site-specific protein modification using lipoic acid ligase and bis-aryl hydrazone formation Tetrazine-Containing Amino Acid for Peptide Modification and Live Cell Labeling Site-specific protein labeling using PRIME and chelation-assisted click chemistry Bioconjugation of therapeutic proteins and enzymes using the expanded set of genetically encoded amino acids.Enzymatic labeling of proteins: techniques and approaches Live cell imaging of single genomic loci with quantum dot-labeled TALEs.Fast and Tight Boronate Formation for Click Bioorthogonal Conjugation.Site-specific labeling of proteins and peptides with trans-cyclooctene containing handles capable of tetrazine ligation.Two rapid catalyst-free click reactions for in vivo protein labeling of genetically encoded strained alkene/alkyne functionalities.Genetically encoded unstrained olefins for live cell labeling with tetrazine dyes.Opportunities for multicomponent hybrid hydrogels in biomedical applications "Turn-on" protein fluorescence: in situ formation of cyanine dyes Methods to Make Homogenous Antibody Drug Conjugates.Conformationally Strained trans-Cyclooctene with Improved Stability and Excellent Reactivity in Tetrazine Ligation.An efficient and mild oxidant for the synthesis of s-tetrazines.Improved metabolic stability for 18F PET probes rapidly constructed via tetrazine trans-cyclooctene ligation.Optical control of endogenous proteins with a photoswitchable conditional subunit reveals a role for TREK1 in GABA(B) signaling.Discovery of new mutually orthogonal bioorthogonal cycloaddition pairs through computational screening Genetic Encoding of bicyclononynes and trans-cyclooctenes for site-specific protein labeling in vitro and in live mammalian cells via rapid fluorogenic Diels-Alder reactions.Designing degradable hydrogels for orthogonal control of cell microenvironments.Facile and efficient Lewis acid catalyzed synthesis of an asymmetric tetrazine useful for bio-orthogonal click chemistry applications.trans-Cyclooctene--a stable, voracious dienophile for bioorthogonal labeling.Exploring bacterial cell biology with single-molecule tracking and super-resolution imaging.Fluorogenic protein labeling using a genetically encoded unstrained alkene.Expanding room for tetrazine ligations in the in vivo chemistry toolbox.What precision-protein-tuning and nano-resolved single molecule sciences can do for each other.Strained alkenes in natural product synthesis.Inverse electron demand Diels-Alder (iEDDA)-initiated conjugation: a (high) potential click chemistry scheme.The inverse electron demand Diels-Alder click reaction in radiochemistry.Bioorthogonal chemistry: implications for pretargeted nuclear (PET/SPECT) imaging and therapy.Ligation strategies for targeting liposomal nanocarriers.Current approaches for RNA labeling in vitro and in cells based on click reactions.Design strategies for bioorthogonal smart probes Activity-based protein profiling: recent advances in probe development and applications.Selective chemical labeling of proteins.Peptide-tags for site-specific protein labelling in vitro and in vivo.

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Diels-Alder cycloaddition for fluorophore targeting to specific proteins inside living cells

http://www.wikidata.org/entity/Q24599345

description

2012 nî lūn-bûn

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2012 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2012 թվականի հունվարին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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P2093

Alice Y Ting

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Anupong Tangpeerachaikul

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Daniel S Liu

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Joseph M Fox

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Michael T Taylor

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Ramajeyam Selvaraj

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P2860

Labeling live cells by copper-catalyzed alkyne--azide click chemistry

A fluorophore ligase for site-specific protein labeling inside living cells

Fast, three-dimensional super-resolution imaging of live cells

Tetrazine ligation: fast bioconjugation based on inverse-electron-demand Diels-Alder reactivity

A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes

Specific covalent labeling of recombinant protein molecules inside live cells

Yeast display evolution of a kinetically efficient 13-amino acid substrate for lipoic acid ligase.

Polytriazoles as copper(I)-stabilizing ligands in catalysis.

Redirecting lipoic acid ligase for cell surface protein labeling with small-molecule probes.

An engineered aryl azide ligase for site-specific mapping of protein-protein interactions through photo-cross-linking.

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10.1021/JA209325N

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2

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134

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22176354

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3381951

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