Crystal structure of the catalytic domain of human complement c1s: a serine protease with a handle
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Substrate specificities of recombinant mannan-binding lectin-associated serine proteases-1 and -2X-ray structure of the Ca2+-binding interaction domain of C1s. Insights into the assembly of the C1 complex of complementThe crystal structure of the zymogen catalytic domain of complement protease C1r reveals that a disruptive mechanical stress is required to trigger activation of the C1 complex.C1 inhibitor serpin domain structure reveals the likely mechanism of heparin potentiation and conformational diseaseA Molecular Switch Governs the Interaction between the Human Complement Protease C1s and Its Substrate, Complement C4The Serine Protease Domain of MASP-3: Enzymatic Properties and Crystal Structure in Complex with EcotinStructural basis of the C1q/C1s interaction and its central role in assembly of the C1 complex of complement activationStructure of the haptoglobin-haemoglobin complexCalcium-dependent conformational flexibility of a CUB domain controls activation of the complement serine protease C1rFunctionally distinct NEAT (NEAr Transporter) domains within the Staphylococcus aureus IsdH/HarA protein extract heme from methemoglobin.Complement is activated by IgG hexamers assembled at the cell surface.Deciphering the fine details of c1 assembly and activation mechanisms: "mission impossible"?Elucidation of the substrate specificity of the C1s protease of the classical complement pathway.Mapping surface accessibility of the C1r/C1s tetramer by chemical modification and mass spectrometry provides new insights into assembly of the human C1 complex.The role of the lys628 (192) residue of the complement protease, c1s, in interacting with Peptide and protein substrates.Structure of vaccinia complement protein in complex with heparin and potential implications for complement regulation.Determinants of specificity in coagulation proteases.Purification, crystallization and preliminary X-ray analysis of human mannose-binding lectin-associated serine protease-1 (MASP-1) catalytic region.Polyanion-induced self-association of complement factor H.Analysis of a conformational B cell epitope of human thyroid peroxidase: identification of a tyrosine residue at a strategic location for immunodominance.Sushi Domain-Containing Protein 3: A Potential Target for Breast Cancer.Modular arrangement and secretion of a multidomain serine protease. Evidence for involvement of proline-rich region and N-glycans in the secretion pathway.Structural and functional influences of coagulation factor XIII subunit B heterozygous missense mutants.Complement C1r and C1s genes are duplicated in the mouse: differential expression generates alternative isomorphs in the liver and in the male reproductive system.Assembly and enzymatic properties of the catalytic domain of human complement protease C1r.Modulation of the proteolytic activity of the complement protease C1s by polyanions: implications for polyanion-mediated acceleration of interaction between C1s and SERPING1.Functional characterization of complement proteases C1s/mannan-binding lectin-associated serine protease-2 (MASP-2) chimeras reveals the higher C4 recognition efficacy of the MASP-2 complement control protein modules.The Structural Basis for Complement Inhibition by Gigastasin, a Protease Inhibitor from the Giant Amazon Leech.Leishmania donovani Inhibitor of Serine Peptidases 2 Mediated Inhibition of Lectin Pathway and Upregulation of C5aR Signaling Promote Parasite Survival inside Host.Antibody CR1-2B11 recognizes a non-polymorphic epitope of human CR1 (CD35).Structural model of haptoglobin and its complex with the anticoagulant ecotin variants: structure-activity relationship study and analysis of interactions.Mechanism-based selection of a potent kallikrein-related peptidase 7 inhibitor from a versatile library based on the sunflower trypsin inhibitor SFTI-1
P2860
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P2860
Crystal structure of the catalytic domain of human complement c1s: a serine protease with a handle
description
2000 nî lūn-bûn
@nan
2000 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Crystal structure of the catal ...... serine protease with a handle
@ast
Crystal structure of the catal ...... serine protease with a handle
@en
Crystal structure of the catal ...... serine protease with a handle
@nl
type
label
Crystal structure of the catal ...... serine protease with a handle
@ast
Crystal structure of the catal ...... serine protease with a handle
@en
Crystal structure of the catal ...... serine protease with a handle
@nl
altLabel
Crystal structure of the catal ...... serine protease with a handle
@en
prefLabel
Crystal structure of the catal ...... serine protease with a handle
@ast
Crystal structure of the catal ...... serine protease with a handle
@en
Crystal structure of the catal ...... serine protease with a handle
@nl
P2093
P2860
P356
P1433
P1476
Crystal structure of the catal ...... serine protease with a handle
@en
P2093
C Gaboriaud
G J Arlaud
J C Fontecilla-Camps
P2860
P304
P356
10.1093/EMBOJ/19.8.1755
P407
P577
2000-04-17T00:00:00Z