Variation in nicotinic acetylcholine receptor genes is associated with multiple substance dependence phenotypes - Test2 - elhamkhani - TriplyDB

Variation in nicotinic acetylcholine receptor genes is associated with multiple substance dependence phenotypes

Variation in nicotinic acetylcholine receptor genes is associated with multiple substance dependence phenotypes

http://www.wikidata.org/entity/Q24601922

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Common liability to addiction and "gateway hypothesis": theoretical, empirical and evolutionary perspective Nicotinic acetylcholine receptors: upregulation, age-related effects and associations with drug use Genetic vulnerability and susceptibility to substance dependence.Nicotinic receptor modulation to treat alcohol and drug dependence Genome-wide association study confirms lung cancer susceptibility loci on chromosomes 5p15 and 15q25 in an African-American population Alternative CHRNB4 3'-UTRs mediate the allelic effects of SNP rs1948 on gene expression ACSL6 is associated with the number of cigarettes smoked and its expression is altered by chronic nicotine exposure.Nicotine enhances alcohol intake and dopaminergic responses through β2* and β4* nicotinic acetylcholine receptors.Profiling of childhood adversity-associated DNA methylation changes in alcoholic patients and healthy controls.CHRNA5 and CHRNA3 variants and level of neuroticism in young adult Mexican American men and women.Mechanisms and genetic factors underlying co-use of nicotine and alcohol or other drugs of abuse.The α3β4* nicotinic ACh receptor subtype mediates physical dependence to morphine: mouse and human studies.Neuronal nicotinic acetylcholine receptors: common molecular substrates of nicotine and alcohol dependence.Nicotinic α5 receptor subunit mRNA expression is associated with distant 5' upstream polymorphisms.Role of a genetic variant on the 15q25.1 lung cancer susceptibility locus in smoking-associated nasopharyngeal carcinoma.Scientific overview: 2013 BBC plenary symposium on tobacco addiction.A complex interplay between personality domains, marital status and a variant in CHRNA5 on the risks of cocaine, nicotine dependences and cocaine-induced paranoia.Variation in the nicotinic acetylcholine receptor gene cluster CHRNA5-CHRNA3-CHRNB4 and its interaction with recent tobacco use influence cognitive flexibility.A common genetic variant in the neurexin superfamily member CNTNAP2 is associated with increased risk for selective mutism and social anxiety-related traits A novel cholinergic action of alcohol and the development of tolerance to that effect in Caenorhabditis elegans.Cis-regulatory variants affect CHRNA5 mRNA expression in populations of African and European ancestry.Patterns of nicotinic receptor antagonism: nicotine discrimination studies.Linkage analyses of stimulant dependence, craving, and heavy use in American Indians.Rare nonsynonymous variants in alpha-4 nicotinic acetylcholine receptor gene protect against nicotine dependence.Childhood adversity increases risk for nicotine dependence and interacts with α5 nicotinic acetylcholine receptor genotype specifically in males.New associations of the genetic polymorphisms in nicotinic receptor genes with the risk of lung cancer.Analysis of detailed phenotype profiles reveals CHRNA5-CHRNA3-CHRNB4 gene cluster association with several nicotine dependence traits.A multiancestry study identifies novel genetic associations with CHRNA5 methylation in human brain and risk of nicotine dependence.The genetics of addiction-a translational perspective Externalizing behaviors are associated with SNPs in the CHRNA5/CHRNA3/CHRNB4 gene cluster.Recent Advances in Nicotinic Receptor Signaling in Alcohol Abuse and Alcoholism.CHRNA5/A3/B4 Variant rs3743078 and Nicotine-Related Phenotypes: Indirect Effects Through Nicotine Craving.Variants in the 15q25 gene cluster are associated with risk for schizophrenia and bipolar disorder.A CHRNA5 Smoking Risk Variant Decreases the Aversive Effects of Nicotine in Humans.Variants near CHRNB3-CHRNA6 are associated with DSM-5 cocaine use disorder: evidence for pleiotropy.Scrutiny of the CHRNA5-CHRNA3-CHRNB4 smoking behavior locus reveals a novel association with alcohol use in a Finnish population based study Genetic influences on nicotinic α5 receptor (CHRNA5) CpG methylation and mRNA expression in brain and adipose tissue.Nominal association with CHRNA4 variants and nicotine dependence.The CHRNA5/A3/B4 gene cluster and tobacco, alcohol, cannabis, inhalants and other substance use initiation: replication and new findings using mixture analyses.Probability and predictors of transition from abuse to dependence on alcohol, cannabis, and cocaine: results from the National Epidemiologic Survey on Alcohol and Related Conditions.

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Variation in nicotinic acetylcholine receptor genes is associated with multiple substance dependence phenotypes

http://www.wikidata.org/entity/Q24601922

description

2010 nî lūn-bûn

@nan

2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Variation in nicotinic acetylc ...... ubstance dependence phenotypes

@ast

Variation in nicotinic acetylc ...... ubstance dependence phenotypes

@en

Variation in nicotinic acetylc ...... ubstance dependence phenotypes

@nl

type

label

Variation in nicotinic acetylc ...... ubstance dependence phenotypes

@ast

Variation in nicotinic acetylc ...... ubstance dependence phenotypes

@en

Variation in nicotinic acetylc ...... ubstance dependence phenotypes

@nl

prefLabel

Variation in nicotinic acetylc ...... ubstance dependence phenotypes

@ast

Variation in nicotinic acetylc ...... ubstance dependence phenotypes

@en

Variation in nicotinic acetylc ...... ubstance dependence phenotypes

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Neuropsychopharmacology

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Variation in nicotinic acetylc ...... ubstance dependence phenotypes

@en

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Albert J Arias

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David Oslin

http://www.w3.org/2001/XMLSchema#string

Henry R Kranzler

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Raymond F Anton

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Yi Yu

http://www.w3.org/2001/XMLSchema#string

P2860

Inference of population structure using multilocus genotype data

PLINK: a tool set for whole-genome association and population-based linkage analyses

Haploview: analysis and visualization of LD and haplotype maps

Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1

Novel genes identified in a high-density genome wide association study for nicotine dependence

A variant associated with nicotine dependence, lung cancer and peripheral arterial disease

A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25

Genome-wide linkage scan for nicotine dependence in European Americans and its converging results with African Americans in the Mid-South Tobacco Family sample.

The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans.

Association of CHRN genes with "dizziness" to tobacco.

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1921-31

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10.1038/NPP.2010.64

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9

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35

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Lindsay A. Farrer

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2010-08-01T00:00:00Z

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44614069

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1043987411

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20485328

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3055642

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