Mediation of NGF signaling by post-translational inhibition of HES-1, a basic helix-loop-helix repressor of neuronal differentiation
about
Oscillatory regulation of Hes1: Discrete stochastic delay modelling and simulationInterleukin 3-dependent activation of DREAM is involved in transcriptional silencing of the apoptotic Hrk gene in hematopoietic progenitor cells.Isolation of a murine homologue of the Drosophila neuralized gene, a gene required for axonemal integrity in spermatozoa and terminal maturation of the mammary glandThe basic helix-loop-helix region of the transcriptional repressor hairy and enhancer of split 1 is preorganized to bind DNAHes-1 SUMOylation by protein inhibitor of activated STAT1 enhances the suppressing effect of Hes-1 on GADD45α expression to increase cell survivalAdoptive transfer of heme oxygenase-1 (HO-1)-modified macrophages rescues the nuclear factor erythroid 2-related factor (Nrf2) antiinflammatory phenotype in liver ischemia/reperfusion injuryHes1 directly controls cell proliferation through the transcriptional repression of p27Kip1Hes1 and Hes3 regulate maintenance of the isthmic organizer and development of the mid/hindbrain.Roles of the basic helix-loop-helix genes Hes1 and Hes5 in expansion of neural stem cells of the developing brainProgenitor cell proliferation in the retina is dependent on Notch-independent Sonic hedgehog/Hes1 activityGeneration of structurally and functionally distinct factors from the basic helix-loop-helix gene Hes3 by alternative first exons.NK-like homeodomain proteins activate NOTCH3-signaling in leukemic T-cells.Hes-6, an inhibitor of Hes-1, is regulated by 17beta-estradiol and promotes breast cancer cell proliferationExposure to 1800 MHz radiofrequency radiation impairs neurite outgrowth of embryonic neural stem cellsHES-1 repression of differentiation and proliferation in PC12 cells: role for the helix 3-helix 4 domain in transcription repression.Human homolog of Drosophila Hairy and enhancer of split 1, Hes1, negatively regulates δ-catenin (CTNND2) expression in cooperation with E2F1 in prostate cancerTranscription factor Hes1 modulates osteoarthritis development in cooperation with calcium/calmodulin-dependent protein kinase 2.Delta-Notch--and then? Protein interactions and proposed modes of repression by Hes and Hey bHLH factorsThe transcriptional repressor Hes1 attenuates inflammation by regulating transcription elongationHES1 is a master regulator of glucocorticoid receptor-dependent gene expression.Nanomedicine boosts neurogenesis: new strategies for brain repair.E2F4 actively promotes the initiation and maintenance of nerve growth factor-induced cell differentiationThe notch pathway intermediate HES-1 silences CD4 gene expression.Hes1: the maestro in neurogenesis.Collier/OLF/EBF-dependent transcriptional dynamics control pharyngeal muscle specification from primed cardiopharyngeal progenitors.The bHLH gene Hes1 is essential for expansion of early T cell precursors.Protein kinase C activates human lipocalin-type prostaglandin D synthase gene expression through de-repression of notch-HES signaling and enhancement of AP-2 beta function in brain-derived TE671 cells.GD3 synthase gene expression in PC12 cells results in the continuous activation of TrkA and ERK1/2 and enhanced proliferation.BMPs inhibit neurogenesis by a mechanism involving degradation of a transcription factor.Connective tissue growth factor enhances osteoblastogenesis in vitro.Repression of chondrogenesis through binding of notch signaling proteins HES-1 and HEY-1 to N-box domains in the COL2A1 enhancer site.Neuroblast differentiation during development and in neuroblastoma requires KIF1Bβ-mediated transport of TRKA.Notch-mediated lateral inhibition is an evolutionarily conserved mechanism patterning the ectoderm in echinoids.R-esp1, a rat homologue of drosophila groucho, is differentially expressed after optic nerve crush and mediates NGF-induced survival of PC12 cells.Pleiotropic Hes-1 Concomitant with its Differential Activation Mediates Neural Stem Cell Maintenance and Radial Glial Propensity in Developing Neocortex.
P2860
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P2860
Mediation of NGF signaling by post-translational inhibition of HES-1, a basic helix-loop-helix repressor of neuronal differentiation
description
1997 nî lūn-bûn
@nan
1997 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Mediation of NGF signaling by ...... or of neuronal differentiation
@ast
Mediation of NGF signaling by ...... or of neuronal differentiation
@en
Mediation of NGF signaling by ...... or of neuronal differentiation
@nl
type
label
Mediation of NGF signaling by ...... or of neuronal differentiation
@ast
Mediation of NGF signaling by ...... or of neuronal differentiation
@en
Mediation of NGF signaling by ...... or of neuronal differentiation
@nl
prefLabel
Mediation of NGF signaling by ...... or of neuronal differentiation
@ast
Mediation of NGF signaling by ...... or of neuronal differentiation
@en
Mediation of NGF signaling by ...... or of neuronal differentiation
@nl
P2093
P2860
P3181
P356
P1433
P1476
Mediation of NGF signaling by ...... or of neuronal differentiation
@en
P2093
P2860
P304
P3181
P356
10.1101/GAD.11.23.3168
P407
P577
1997-12-01T00:00:00Z