Young dentate granule cells mediate pattern separation, whereas old granule cells facilitate pattern completion - Test2 - elhamkhani - TriplyDB

Young dentate granule cells mediate pattern separation, whereas old granule cells facilitate pattern completion

Young dentate granule cells mediate pattern separation, whereas old granule cells facilitate pattern completion

http://www.wikidata.org/entity/Q24605371

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The mechanisms for pattern completion and pattern separation in the hippocampus Superior pattern processing is the essence of the evolved human brain Differential roles of the dopamine 1-class receptors, D1R and D5R, in hippocampal dependent memory Genetic control of adult neurogenesis: interplay of differentiation, proliferation and survival modulates new neurons function, and memory circuits A neural circuit for memory specificity and generalization Aerobic Exercise as a Tool to Improve Hippocampal Plasticity and Function in Humans: Practical Implications for Mental Health Treatment Are Anxiety Disorders Associated with Accelerated Aging? A Focus on Neuroprogression Assigning Function to Adult-Born Neurons: A Theoretical Framework for Characterizing Neural Manipulation of Learning Potential implications of a monosynaptic pathway from mossy cells to adult-born granule cells of the dentate gyrus Involvement of Adult Hippocampal Neurogenesis in Learning and Forgetting.Mesenchymal stem cells secretome as a modulator of the neurogenic niche: basic insights and therapeutic opportunities The Possible Roles of the Dentate Granule Cell's Leptin and Other Ciliary Receptors in Alzheimer's Neuropathology Increasing the resolution of the adult neurogenesis picture Functional circuits of new neurons in the dentate gyrus Impact of lipid nutrition on neural stem/progenitor cells Dynamic learning and memory, synaptic plasticity and neurogenesis: an update A central role for the acid sphingomyelinase/ceramide system in neurogenesis and major depression Monosynaptic Circuit Tracing with Glycoprotein-Deleted Rabies Viruses Physical exercise-induced adult neurogenesis: a good strategy to prevent cognitive decline in neurodegenerative diseases?Differential Structural Development of Adult-Born Septal Hippocampal Granule Cells in the Thy1-GFP Mouse, Nuclear Size as a New Index of Maturation Effect of context exposure after fear learning on memory generalization in mice.Linking pattern completion in the hippocampus to predictive coding in visual cortex.Tracking the Time-Dependent Role of the Hippocampus in Memory Recall Using DREADDs Suppression of adult neurogenesis impairs population coding of similar contexts in hippocampal CA3 region Depletion of primary cilia from mature dentate granule cells impairs hippocampus-dependent contextual memory Neuromodulation of the Feedforward Dentate Gyrus-CA3 Microcircuit Effects of Neurotrophic Support and Amyloid-Targeted Combined Therapy on Adult Hippocampal Neurogenesis in a Transgenic Model of Alzheimer's Disease Protein kinase LKB1 regulates polarized dendrite formation of adult hippocampal newborn neurons PGBD5: a neural-specific intron-containing piggyBac transposase domesticated over 500 million years ago and conserved from cephalochordates to humans Ongoing neurogenesis in the adult dentate gyrus mediates behavioral responses to ambiguous threat cues.Adult Hippocampal Neurogenesis Modulates Fear Learning through Associative and Nonassociative Mechanisms.Prefrontal consolidation supports the attainment of fear memory accuracy Optogenetic dissection of neural circuits underlying emotional valence and motivated behaviors.Smad3 is required for the survival of proliferative intermediate progenitor cells in the dentate gyrus of adult mice Prefrontal microcircuit underlies contextual learning after hippocampal loss Optogenetic stimulation of a hippocampal engram activates fear memory recall.Differential control of learning and anxiety along the dorsoventral axis of the dentate gyrus.Retrograde monosynaptic tracing reveals the temporal evolution of inputs onto new neurons in the adult dentate gyrus and olfactory bulb.In vivo imaging of adult human hippocampal neurogenesis: progress, pitfalls and promise Monosynaptic inputs to new neurons in the dentate gyrus.

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P2860

Young dentate granule cells mediate pattern separation, whereas old granule cells facilitate pattern completion

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2012 nî lūn-bûn

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J.CELL.2012.01.046

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Toshiaki Nakashiba

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P2860

Loss of recent memory after bilateral hippocampal lesions

Monosynaptic restriction of transsynaptic tracing from single, genetically targeted neurons

Neurons born in the adult dentate gyrus form functional synapses with target cells

Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats

Neurogenesis in the adult human hippocampus

Dentate gyrus NMDA receptors mediate rapid pattern separation in the hippocampal network

Enhancement of learning and memory by elevating brain magnesium

Requirement for hippocampal CA3 NMDA receptors in associative memory recall

Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants

Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors

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188-201

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10.1016/J.CELL.2012.01.046

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1

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Susumu Tonegawa

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221862121

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