O6-Methylguanine DNA methyltransferase protein expression in tumor cells predicts outcome of temozolomide therapy in glioblastoma patients - Test2 - elhamkhani - TriplyDB

O6-Methylguanine DNA methyltransferase protein expression in tumor cells predicts outcome of temozolomide therapy in glioblastoma patients

O6-Methylguanine DNA methyltransferase protein expression in tumor cells predicts outcome of temozolomide therapy in glioblastoma patients

http://www.wikidata.org/entity/Q24607903

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Enhanced anti-tumor effect of zoledronic acid combined with temozolomide against human malignant glioma cell expressing O6-methylguanine DNA methyltransferase Temozolomide Resistance in Glioblastoma Cell Lines: Implication of MGMT, MMR, P-Glycoprotein and CD133 Expression Interobserver variation of the histopathological diagnosis in clinical trials on glioma: a clinician's perspective TERT promoter mutations lead to high transcriptional activity under hypoxia and temozolomide treatment and predict poor prognosis in gliomas.Metabolic targeting of EGFRvIII/PDK1 axis in temozolomide resistant glioblastoma.O-methylguanine-DNA methyltransferase (MGMT) mRNA expression predicts outcome in malignant glioma independent of MGMT promoter methylation.Differential expression of miR200a-3p and miR21 in grade II-III and grade IV gliomas: evidence that miR200a-3p is regulated by O⁶-methylguanine methyltransferase and promotes temozolomide responsiveness.A genome-wide miRNA screen revealed miR-603 as a MGMT-regulating miRNA in glioblastomas.Regulation of expression of O6-methylguanine-DNA methyltransferase and the treatment of glioblastoma (Review).Molecular alterations in glioblastoma: potential targets for immunotherapy.MGMT promoter methylation in gliomas-assessment by pyrosequencing and quantitative methylation-specific PCR Prognostic quality of activating TERT promoter mutations in glioblastoma: interaction with the rs2853669 polymorphism and patient age at diagnosis Broad targeting of resistance to apoptosis in cancer.Prognostic significance of telomerase-associated parameters in glioblastoma: effect of patient age.Predictive value of the SLC22A18 protein expression in glioblastoma patients receiving temozolomide therapy.Inhibition of histone deacetylation potentiates the evolution of acquired temozolomide resistance linked to MGMT upregulation in glioblastoma xenografts.Molecular profiling of head and neck squamous cell carcinoma.BACH1 Promotes Temozolomide Resistance in Glioblastoma through Antagonizing the Function of p53.Response of primary glioblastoma cells to therapy is patient specific and independent of cancer stem cell phenotype.Targeting O⁶-methylguanine-DNA methyltransferase with specific inhibitors as a strategy in cancer therapy.Molecular mechanisms of temozolomide resistance in glioblastoma multiforme.Progression of O⁶-methylguanine-DNA methyltransferase and temozolomide resistance in cancer research.Predictive biomarkers investigated in glioblastoma.Polymorphisms in DNA Repair Gene and Susceptibility to Glioma: A Systematic Review and Meta-Analysis Based on 33 Studies with 15 SNPs in 9 Genes.O6-methylguanine DNA methyltransferase expression in tumor cells predicts outcome of radiotherapy plus concomitant and adjuvant temozolomide therapy in patients with primary glioblastoma.Mining the glioma susceptibility genes in children from gene expression profiles and a methylation database.Immunohistochemical profiles of IDH1, MGMT and P53: practical significance for prognostication of patients with diffuse gliomas.Identification of potential therapeutic targets for gliomas by bioinformatics analysis.Pyrrolidine dithiocarbamate sensitizes U251 brain glioma cells to temozolomide via downregulation of MGMT and BCL-XL.MEK-ERK signaling dictates DNA-repair gene MGMT expression and temozolomide resistance of stem-like glioblastoma cells via the MDM2-p53 axis.MGMT expression and promoter methylation status may depend on the site of surgical sample collection within glioblastoma: a possible pitfall in stratification of patients?Concordant association validates MGMT methylation and protein expression as favorable prognostic factors in glioma patients on alkylating chemotherapy (Temozolomide).Promoter methylation and expression of MGMT and the DNA mismatch repair genes MLH1, MSH2, MSH6 and PMS2 in paired primary and recurrent glioblastomas.C1q/TNF-related peptide 8 (CTRP8) promotes temozolomide resistance in human glioblastoma

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O6-Methylguanine DNA methyltransferase protein expression in tumor cells predicts outcome of temozolomide therapy in glioblastoma patients

http://www.wikidata.org/entity/Q24607903

description

2010 nî lūn-bûn

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2010 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2010年の論文

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2010年論文

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2010年論文

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O6-Methylguanine DNA methyltra ...... erapy in glioblastoma patients

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O6-Methylguanine DNA methyltra ...... erapy in glioblastoma patients

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O6-Methylguanine DNA methyltra ...... erapy in glioblastoma patients

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O6-Methylguanine DNA methyltra ...... erapy in glioblastoma patients

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P2860

Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents.

MGMT gene silencing and benefit from temozolomide in glioblastoma.

Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

Recent developments in the use of chemotherapy in brain tumours.

Correlation between O6-methylguanine-DNA methyltransferase and survival in inoperable newly diagnosed glioblastoma patients treated with neoadjuvant temozolomide.

Generating mutations but providing chemosensitivity: the role of O6-methylguanine DNA methyltransferase in human cancer.

MGMT: its role in cancer aetiology and cancer therapeutics.

Clinical relevance of MGMT in the treatment of cancer.

MGMT: key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents.

Chemoradiotherapy in malignant glioma: standard of care and future directions.

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