Mutations in two genes encoding different subunits of a receptor signaling complex result in an identical disease phenotype
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TREM2 Variants in Alzheimer's DiseaseVariant of TREM2 Associated with the Risk of Alzheimer's DiseaseDAP12 signaling: from immune cells to bone modeling and brain myelinationIdentification of soluble TREM-2 in the cerebrospinal fluid and its association with multiple sclerosis and CNS inflammationDAP12/TREM2 deficiency results in impaired osteoclast differentiation and osteoporotic featuresImpaired differentiation of osteoclasts in TREM-2-deficient individualsClinical review: role of triggering receptor expressed on myeloid cells-1 during sepsisGenes associated with Alzheimer's disease: an overview and current statusA Non-inflammatory Role for Microglia in Autism Spectrum DisordersGenetics ignite focus on microglial inflammation in Alzheimer's diseasePhenotypic Heterogeneity of Monogenic Frontotemporal DementiaTREM2 in CNS homeostasis and neurodegenerative diseaseTriggering receptor expressed on myeloid cells receptor family modulators: a patent reviewOsteoimmunology: Major and Costimulatory Pathway Expression Associated with Chronic Inflammatory Induced Bone LossLate-Onset Alzheimer's Disease Genes and the Potentially Implicated PathwaysR47H Variant of TREM2 Associated With Alzheimer Disease in a Large Late-Onset Family: Clinical, Genetic, and Neuropathological StudyNeuroinflammation: Ways in Which the Immune System Affects the BrainTREM-1 (triggering receptor expressed on myeloid cells): a new player in acute inflammatory responsesOsteopetrosis and thalamic hypomyelinosis with synaptic degeneration in DAP12-deficient miceThe receptor TREML4 amplifies TLR7-mediated signaling during antiviral responses and autoimmunityUsing exome sequencing to reveal mutations in TREM2 presenting as a frontotemporal dementia-like syndrome without bone involvementTREM2 and the neuroimmunology of Alzheimer's diseaseTreml4, an Ig superfamily member, mediates presentation of several antigens to T cells in vivo, including protective immunity to HER2 proteinSiglec-15 protein regulates formation of functional osteoclasts in concert with DNAX-activating protein of 12 kDa (DAP12)Hereditary leukoencephalopathy with axonal spheroids: a spectrum of phenotypes from CNS vasculitis to parkinsonism in an adult onset leukodystrophy seriesGenomic variants, genes, and pathways of Alzheimer's disease: An overview.Regulation of microglial survival and proliferation in health and diseases.The role of microglia in brain maintenance: implications for Rett syndrome.Insights into TREM2 biology by network analysis of human brain gene expression data.Neuroinflammation - using big data to inform clinical practice.Neurodegenerative disease mutations in TREM2 reveal a functional surface and distinct loss-of-function mechanismsTREM2-transduced myeloid precursors mediate nervous tissue debris clearance and facilitate recovery in an animal model of multiple sclerosis.Direct induction of ramified microglia-like cells from human monocytes: dynamic microglial dysfunction in Nasu-Hakola disease.LC3, an autophagosome marker, is expressed on oligodendrocytes in Nasu-Hakola disease brains.Altered microglial response to Aβ plaques in APPPS1-21 mice heterozygous for TREM2.Late onset Alzheimer's disease genetics implicates microglial pathways in disease risk.The Pathophysiological Role of Microglia in Dynamic Surveillance, Phagocytosis and Structural Remodeling of the Developing CNS.TREM2/DAP12 Complex Regulates Inflammatory Responses in Microglia via the JNK Signaling Pathway.Linkage analysis of schizophrenia controlling for population substructure.New insights on the role of microglia in synaptic pruning in health and disease
P2860
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P2860
Mutations in two genes encoding different subunits of a receptor signaling complex result in an identical disease phenotype
description
2002 nî lūn-bûn
@nan
2002 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Mutations in two genes encodin ...... an identical disease phenotype
@ast
Mutations in two genes encodin ...... an identical disease phenotype
@en
Mutations in two genes encodin ...... an identical disease phenotype
@nl
type
label
Mutations in two genes encodin ...... an identical disease phenotype
@ast
Mutations in two genes encodin ...... an identical disease phenotype
@en
Mutations in two genes encodin ...... an identical disease phenotype
@nl
prefLabel
Mutations in two genes encodin ...... an identical disease phenotype
@ast
Mutations in two genes encodin ...... an identical disease phenotype
@en
Mutations in two genes encodin ...... an identical disease phenotype
@nl
P2093
P2860
P50
P3181
P356
P1476
Mutations in two genes encodin ...... an identical disease phenotype
@en
P2093
Andrea Salmaggi
Grant Christman
Jami Mandelin
Karine Hovanes
Lisbeth Tranebjaerg
Marino Bianchin
Roxana Miranda
Thomas Bird
Tuula Manninen
P2860
P304
P3181
P356
10.1086/342259
P407
P577
2002-09-01T00:00:00Z