Structural specializations of α(4)β(7), an integrin that mediates rolling adhesion
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Vedolizumab for the treatment of ulcerative colitis and Crohn's diseaseMechanical regulation of T-cell functionsA Small Molecule, Which Competes with MAdCAM-1, Activates Integrin α4β7 and Fails to Prevent Mucosal Transmission of SHIV-SF162P3Dual functions of Rap1 are crucial for T-cell homeostasis and prevention of spontaneous colitis.Complete integrin headpiece opening in eight stepsHow Natalizumab Binds and Antagonizes 4 IntegrinsAn internal ligand-bound, metastable state of a leukocyte integrin, α X β 2Functional Implications of the Binding Mode of a Human Conformation-Dependent V2 Monoclonal Antibody against HIVThe V1V2 Region of HIV-1 gp120 Forms a Five-Stranded Beta Barrel.Small molecule agonist of very late antigen-4 (VLA-4) integrin induces progenitor cell adhesionLigand-induced Epitope Masking: DISSOCIATION OF INTEGRIN α5β1-FIBRONECTIN COMPLEXES ONLY BY MONOCLONAL ANTIBODIES WITH AN ALLOSTERIC MODE OF ACTION.EM structure of the ectodomain of integrin CD11b/CD18 and localization of its ligand-binding site relative to the plasma membrane.Metal ion and ligand binding of integrin α5β1Molecular basis for complement recognition by integrin αXβ2.Identification of New Regions in HIV-1 gp120 Variable 2 and 3 Loops that Bind to α4β7 Integrin Receptor.Structure of the Plexin Ectodomain Bound by Semaphorin-Mimicking Antibodies.Domain 1 of mucosal addressin cell adhesion molecule has an I1-set fold and a flexible integrin-binding loopLeukocyte integrin αLβ2 headpiece structures: The αI domain, the pocket for the internal ligand, and concerted movements of its loops.The unique disulfide bond-stabilized W1 β4-β1 loop in the α4 β-propeller domain regulates integrin α4β7 affinity and signaling.Physiologically relevant binding affinity quantification of monoclonal antibody PF-00547659 to mucosal addressin cell adhesion molecule for in vitro in vivo correlationVedolizumab for the treatment of ulcerative colitis.Binding of HIV-1 virions to α4β 7 expressing cells and impact of antagonizing α4β 7 on HIV-1 infection of primary CD4+ T cells.Can Integrin Agonists Have Cards to Play against Cancer? A Literature Survey of Small Molecules Integrin ActivatorsAmmonium trichloro [1,2-ethanediolato-O,O']-tellurate cures experimental visceral leishmaniasis by redox modulation of Leishmania donovani trypanothione reductase and inhibiting host integrin linked PI3K/Akt pathway.The Role of Integrin Expressing Cells in Modulating Disease Susceptibility and Progression (January 2016).Cellular immune surveillance of central nervous system bypasses blood-brain barrier and blood-cerebrospinal-fluid barrier: revealed with the New Marburg cerebrospinal-fluid model in healthy humans.A Lupus-Associated Mac-1 Variant Has Defects in Integrin Allostery and Interaction with Ligands under ForceAtypical interactions of integrin αVβ8 with pro-TGF-β1.The hydrophobic contacts between the center of the βI domain and the α1/α7 helices are crucial for the low-affinity state of integrin α4 β7.Integrin α4β7 Blockade Preferentially Impacts CCR6+ Lymphocyte Subsets in Blood and Mucosal Tissues of Naive Rhesus Macaques.High integrin αVβ6 affinity reached by hybrid domain deletion slows ligand-binding on-rate.The Role of Integrin α4β7 in HIV Pathogenesis and Treatment.Select gp120 V2 domain specific antibodies derived from HIV and SIV infection and vaccination inhibit gp120 binding to α4β7
P2860
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P2860
Structural specializations of α(4)β(7), an integrin that mediates rolling adhesion
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Structural specializations of α(4)β(7), an integrin that mediates rolling adhesion
@ast
Structural specializations of α(4)β(7), an integrin that mediates rolling adhesion
@en
Structural specializations of α(4)β(7), an integrin that mediates rolling adhesion
@nl
type
label
Structural specializations of α(4)β(7), an integrin that mediates rolling adhesion
@ast
Structural specializations of α(4)β(7), an integrin that mediates rolling adhesion
@en
Structural specializations of α(4)β(7), an integrin that mediates rolling adhesion
@nl
altLabel
Structural specializations of α 4 β 7 , an integrin that mediates rolling adhesion
@en
prefLabel
Structural specializations of α(4)β(7), an integrin that mediates rolling adhesion
@ast
Structural specializations of α(4)β(7), an integrin that mediates rolling adhesion
@en
Structural specializations of α(4)β(7), an integrin that mediates rolling adhesion
@nl
P2093
P2860
P3181
P356
P1476
Structural specializations of α(4)β(7), an integrin that mediates rolling adhesion
@en
P2093
JianFeng Chen
Jianghai Zhu
Thomas Walz
Timothy A Springer
P2860
P304
P3181
P356
10.1083/JCB.201110023
P407
P577
2012-01-01T00:00:00Z