Group II metabotropic glutamate receptor agonist ameliorates MK801-induced dysfunction of NMDA receptors via the Akt/GSK-3β pathway in adult rat prefrontal cortex
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Secreted phospholipase A2 involvement in neurodegeneration: differential testing of prosurvival and anti-inflammatory effects of enzyme inhibitionPerspectives on the mGluR2/3 agonists as a therapeutic target for schizophrenia: Still promising or a dead end?Glycogen synthase kinase-3β inhibition in the medial prefrontal cortex mediates paradoxical amphetamine action in a mouse model of ADHD.Pregnenolone sulfate normalizes schizophrenia-like behaviors in dopamine transporter knockout mice through the AKT/GSK3β pathway.GABA transporter-1 deficiency confers schizophrenia-like behavioral phenotypes.LY395756, an mGluR2 agonist and mGluR3 antagonist, enhances NMDA receptor expression and function in the normal adult rat prefrontal cortex, but fails to improve working memory and reverse MK801-induced working memory impairment.Clozapine acts as an agonist at serotonin 2A receptors to counter MK-801-induced behaviors through a βarrestin2-independent activation of AktThe metabotropic glutamate 2/3 receptor agonist LY379268 counteracted ketamine-and apomorphine-induced performance deficits in the object recognition task, but not object location task, in rats.Group II metabotropic glutamate receptor agonist LY379268 regulates AMPA receptor trafficking in prefrontal cortical neurons.Paraventricular nucleus Sim1 neuron ablation mediated obesity is resistant to high fat diet.Prolonged exposure to NMDAR antagonist induces cell-type specific changes of glutamatergic receptors in rat prefrontal cortex.The group II metabotropic glutamate receptor agonist LY379268 reduces toluene-induced enhancement of brain-stimulation reward and behavioral disturbances.Gestational methylazoxymethanol exposure leads to NMDAR dysfunction in hippocampus during early development and lasting deficits in learningNMDA hypofunction as a convergence point for progression and symptoms of schizophreniaNeuroglialpharmacology: myelination as a shared mechanism of action of psychotropic treatments.Serotonin-glutamate and serotonin-dopamine reciprocal interactions as putative molecular targets for novel antipsychotic treatments: from receptor heterodimers to postsynaptic scaffolding and effector proteins.GSK3β Hyperactivity during an Early Critical Period Impairs Prefrontal Synaptic Plasticity and Induces Lasting Deficits in Spine Morphology and Working Memory.Enhancement of social novelty discrimination by positive allosteric modulators at metabotropic glutamate 5 receptors: adolescent administration prevents adult-onset deficits induced by neonatal treatment with phencyclidine.Distinct Synaptic Strengthening of the Striatal Direct and Indirect Pathways Drives Alcohol Consumption.Juvenile treatment with a novel mGluR2 agonist/mGluR3 antagonist compound, LY395756, reverses learning deficits and cognitive flexibility impairments in adults in a neurodevelopmental model of schizophrenia.Juvenile treatment with mGluR2/3 agonist prevents schizophrenia-like phenotypes in adult by acting through GSK3β.Stress-induced changes in social dominance are scaled by AMPA-type glutamate receptor phosphorylation in the medial prefrontal cortexInvestigating the role of mGluR2 versus mGluR3 in antipsychotic-like effects, sleep-wake architecture and network oscillatory activity using novel Han Wistar rats lacking mGluR2 expression
P2860
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P2860
Group II metabotropic glutamate receptor agonist ameliorates MK801-induced dysfunction of NMDA receptors via the Akt/GSK-3β pathway in adult rat prefrontal cortex
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
name
Group II metabotropic glutamat ...... in adult rat prefrontal cortex
@ast
Group II metabotropic glutamat ...... in adult rat prefrontal cortex
@en
Group II metabotropic glutamat ...... in adult rat prefrontal cortex
@nl
type
label
Group II metabotropic glutamat ...... in adult rat prefrontal cortex
@ast
Group II metabotropic glutamat ...... in adult rat prefrontal cortex
@en
Group II metabotropic glutamat ...... in adult rat prefrontal cortex
@nl
prefLabel
Group II metabotropic glutamat ...... in adult rat prefrontal cortex
@ast
Group II metabotropic glutamat ...... in adult rat prefrontal cortex
@en
Group II metabotropic glutamat ...... in adult rat prefrontal cortex
@nl
P2093
P2860
P356
P1476
Group II metabotropic glutamat ...... in adult rat prefrontal cortex
@en
P2093
Alicia E Adelman
Jed S Shumsky
Melissa A Snyder
Ruby Y Gao
Wen-Jun Gao
Wentong Zhang
Yan-Chun Li
P2860
P2888
P304
P356
10.1038/NPP.2011.12
P407
P577
2011-02-16T00:00:00Z
P5875
P6179
1027289906