Joubert syndrome Arl13b functions at ciliary membranes and stabilizes protein transport in Caenorhabditis elegans
about
TMEM237 is mutated in individuals with a Joubert syndrome related disorder and expands the role of the TMEM family at the ciliary transition zoneCCDC41 is required for ciliary vesicle docking to the mother centrioleDisruption of CEP290 microtubule/membrane-binding domains causes retinal degenerationCellular Mechanisms of Ciliary Length ControlMolecular views of Arf-like small GTPases in cilia and ciliopathiesRab and Arf proteins in genetic diseasesCiliary subcompartments: how are they established and what are their functions?Compartments within a compartment: what C. elegans can tell us about ciliary subdomain composition, biogenesis, function, and diseaseConserved Genetic Interactions between Ciliopathy Complexes Cooperatively Support Ciliogenesis and Ciliary SignalingThe nephronophthisis-related gene ift-139 is required for ciliogenesis in Caenorhabditis elegansActive transport and diffusion barriers restrict Joubert Syndrome-associated ARL13B/ARL-13 to an Inv-like ciliary membrane subdomainKIAA0556 is a novel ciliary basal body component mutated in Joubert syndromeMKS5 and CEP290 Dependent Assembly Pathway of the Ciliary Transition ZoneCrystal structure of the small GTPase Arl6/BBS3 fromTrypanosoma bruceiStructural insights into the small G-protein Arl13B and implications for Joubert syndromeThe small GTPases ARL-13 and ARL-3 coordinate intraflagellar transport and ciliogenesisA transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition.The emerging role of Arf/Arl small GTPases in cilia and ciliopathies.ARL13B, PDE6D, and CEP164 form a functional network for INPP5E ciliary targetingTrafficking in and to the primary cilium.The IFT-A complex regulates Shh signaling through cilia structure and membrane protein traffickingEndocytosis genes facilitate protein and membrane transport in C. elegans sensory ciliaArl13b-regulated cilia activities are essential for polarized radial glial scaffold formationArl13b in primary cilia regulates the migration and placement of interneurons in the developing cerebral cortexArl13b regulates ciliogenesis and the dynamic localization of Shh signaling proteinsAn siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genesThe AP-1 clathrin adaptor facilitates cilium formation and functions with RAB-8 in C. elegans ciliary membrane transport.Control of vertebrate intraflagellar transport by the planar cell polarity effector FuzFrom the cytoplasm into the cilium: bon voyage.Diverse cell type-specific mechanisms localize G protein-coupled receptors to Caenorhabditis elegans sensory ciliaCryo-electron tomography reveals conserved features of doublet microtubules in flagella.Ciliopathies: the trafficking connection.The retinitis pigmentosa protein RP2 interacts with polycystin 2 and regulates cilia-mediated vertebrate development.The intracellular dynamic of protein palmitoylationCby1 promotes Ahi1 recruitment to a ring-shaped domain at the centriole-cilium interface and facilitates proper cilium formation and function.Arl13b regulates endocytic recycling traffic.The nphp-2 and arl-13 genetic modules interact to regulate ciliogenesis and ciliary microtubule patterning in C. elegans.Ciliopathy proteins establish a bipartite signaling compartment in a C. elegans thermosensory neuronTubulin glycylases are required for primary cilia, control of cell proliferation and tumor development in colon.The ciliopathy gene cc2d2a controls zebrafish photoreceptor outer segment development through a role in Rab8-dependent vesicle trafficking.
P2860
Q24299114-AADEE3F3-E467-4842-80E8-2C885EFDFF7DQ24337341-A4C2C585-D51A-43FF-9B89-218C0B7F1BC9Q24617850-9AC1ECD6-2B97-4E44-A929-9B2C5149BA57Q26769756-E6CE9D07-4188-4F75-9941-10A9BF843885Q26830180-D6AE99FA-3D16-4E5A-9A4B-51FD4B4AEB0DQ26862704-8D74BE83-2576-4647-83EB-A97697445ADDQ26999913-E9C437EA-B14A-459E-A9F6-162B8C895C56Q27025518-760626B8-6558-442C-A855-A4F782072E22Q27310130-7F989560-E91E-4355-9EB1-97A8B9A0750EQ27317381-DA447E9C-E5CE-4DBE-B176-01C18F9BAD11Q27318730-1CC6A983-7E15-4012-AB18-0E12390CBD1EQ27336381-8EC83852-0294-4C8C-85F6-30D02198FD09Q27343217-DC2FB042-3586-401F-BA18-FC3B5CC028DFQ27675243-60417A69-7453-4FDA-A0DD-367C9772FD10Q27687376-244A3AF8-8E62-48F7-8E06-E3A10339D79DQ28000022-4D854DC6-4D72-44D6-ADE4-F9255E08E70BQ28000057-5675F000-7AE0-4AD7-A8B1-5BEAC5BDC0F7Q28000091-FC66F163-FE1F-4495-BD45-B531F3516B6BQ28000117-F4086348-8BEF-4A4E-8890-D598EC333131Q28000124-08413E91-48FF-4D95-A373-4723C774D10BQ28506316-9A38A439-E553-4974-BAAE-42F3E6711CCDQ28507599-620E8507-3DA0-4782-A027-E2F340765596Q28507617-1974C66A-D785-46C8-A17E-9B5A8849812EQ28513840-2EF9377B-79D1-4201-B3B0-B99578D1C1C9Q28586066-D01212C5-AE9E-4926-9CEC-BC9424B14CC5Q29144923-7A732F26-BB73-4C3A-914B-D7607CBD7285Q30497242-604EF720-EEB6-4189-B616-993089D6D837Q30519557-999BEA93-2926-4BB7-B1EA-DA15FAE507ACQ33728229-ACC81FA8-5C17-41E6-AA1A-F9D25892E7F7Q33779611-2A0AFADA-3093-4C24-A475-43446B0380E5Q34022751-1F19845C-39AD-4F7C-877C-623195EFDBABQ34207085-09FB5CB5-F9F9-4D66-BF02-CE20C071D833Q34211989-644F5C1A-2EA4-4AA2-B892-5BF4D6338C4FQ34439629-10581EC4-C5B5-481D-9DA4-D6251A50335AQ34504028-46C09188-78E8-47B0-9959-0F8AA68076C2Q34504287-2BD0244D-DD2E-402C-908C-7CAAB783432CQ34679993-5E58B20A-04BB-4287-B6DA-D8E8039319E0Q34698580-7126F9CE-35F7-4197-B9C0-9982E0861FF5Q34806540-D955115E-2BC5-4EC1-841A-6AF48CA90BCDQ35225255-C04D8B59-2AB4-4550-A6F2-990A92FA6BC4
P2860
Joubert syndrome Arl13b functions at ciliary membranes and stabilizes protein transport in Caenorhabditis elegans
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Joubert syndrome Arl13b functi ...... port in Caenorhabditis elegans
@ast
Joubert syndrome Arl13b functi ...... port in Caenorhabditis elegans
@en
Joubert syndrome Arl13b functi ...... port in Caenorhabditis elegans
@nl
type
label
Joubert syndrome Arl13b functi ...... port in Caenorhabditis elegans
@ast
Joubert syndrome Arl13b functi ...... port in Caenorhabditis elegans
@en
Joubert syndrome Arl13b functi ...... port in Caenorhabditis elegans
@nl
prefLabel
Joubert syndrome Arl13b functi ...... port in Caenorhabditis elegans
@ast
Joubert syndrome Arl13b functi ...... port in Caenorhabditis elegans
@en
Joubert syndrome Arl13b functi ...... port in Caenorhabditis elegans
@nl
P2093
P2860
P50
P3181
P356
P1476
Joubert syndrome Arl13b functi ...... port in Caenorhabditis elegans
@en
P2093
Christian Foley-Fisher
David Cottell
Kenji Kontani
Oliver E Blacque
Tiina Toivenon
Toshiaki Katada
P2860
P304
P3181
P356
10.1083/JCB.200908133
P407
P5008
P577
2010-03-22T00:00:00Z