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Selective ROCK2 inhibition in focal cerebral ischemia

Selective ROCK2 inhibition in focal cerebral ischemia

http://www.wikidata.org/entity/Q24614558

about

Novel Insights into the Roles of Rho Kinase in Cancer Rho-associated kinase signalling and the cancer microenvironment: novel biological implications and therapeutic opportunities Rho kinase as a target for cerebral vascular disorders Cutting Edge: Selective Oral ROCK2 Inhibitor Reduces Clinical Scores in Patients with Psoriasis Vulgaris and Normalizes Skin Pathology via Concurrent Regulation of IL-17 and IL-10 Selective inhibition of brain endothelial Rho-kinase-2 provides optimal protection of an in vitro blood-brain barrier from tissue-type plasminogen activator and plasmin.Rho kinase proteins display aberrant upregulation in vascular tumors and contribute to vascular tumor growth.Selective oral ROCK2 inhibitor down-regulates IL-21 and IL-17 secretion in human T cells via STAT3-dependent mechanism.The selectivity and promiscuity of brain-neuroregenerative inhibitors between ROCK1 and ROCK2 isoforms: An integration of SB-QSSR modelling, QM/MM analysis and in vitro kinase assay.Kinase targets in CNS drug discovery.Improving Reperfusion Therapies in the Era of Mechanical Thrombectomy Rho Kinases and Cardiac Remodeling.Rho kinase inhibitors: a patent review (2014 - 2016).New treatment directions for IPF: current status of ongoing and upcoming clinical trials.Rho-associated protein kinases as therapeutic targets for both vascular and parenchymal pathologies in Alzheimer's disease.Heterogeneous Impact of ROCK2 on Carotid and Cerebrovascular Function Effects of CC-chemokine receptor 5 on ROCK2 and P-MLC2 expression after focal cerebral ischaemia-reperfusion injury in rats.Isoform-specific targeting of ROCK proteins in immune cells.Investigational drugs for idiopathic pulmonary fibrosis.Idiopathic Pulmonary Fibrosis: Molecular Endotypes of Fibrosis Stratifying Existing and Emerging Therapies.ROCK as a therapeutic target for ischemic stroke.Targeting the RhoA-ROCK pathway to reverse T-cell dysfunction in SLE.Additive effects of the Rho kinase inhibitor Y-27632 and vardenafil on relaxation of the corpus cavernosum tissue of patients with erectile dysfunction and clinical phosphodiesterase type 5 inhibitor failure.Aberrant T Cell Signaling and Subsets in Systemic Lupus Erythematosus.Rho-kinase inhibitors do not expand hematoma volume in acute experimental intracerebral hemorrhage.

P2860

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P2860

Selective ROCK2 inhibition in focal cerebral ischemia

http://www.wikidata.org/entity/Q24614558

description

2014 nî lūn-bûn

@nan

2014 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

Selective ROCK2 inhibition in focal cerebral ischemia

@ast

Selective ROCK2 inhibition in focal cerebral ischemia

@en

Selective ROCK2 inhibition in focal cerebral ischemia

@nl

type

label

Selective ROCK2 inhibition in focal cerebral ischemia

@ast

Selective ROCK2 inhibition in focal cerebral ischemia

@en

Selective ROCK2 inhibition in focal cerebral ischemia

@nl

prefLabel

Selective ROCK2 inhibition in focal cerebral ischemia

@ast

Selective ROCK2 inhibition in focal cerebral ischemia

@en

Selective ROCK2 inhibition in focal cerebral ischemia

@nl

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P1433

Annals of clinical and translational neurology

P1476

Selective ROCK2 inhibition in focal cerebral ischemia

@en

P2093

Ali Daneshmand

http://www.w3.org/2001/XMLSchema#string

Aygul Balcioglu

http://www.w3.org/2001/XMLSchema#string

Daniel von Bornstadt

http://www.w3.org/2001/XMLSchema#string

Eng H Lo

http://www.w3.org/2001/XMLSchema#string

Esther Yu

http://www.w3.org/2001/XMLSchema#string

Fanny Herisson

http://www.w3.org/2001/XMLSchema#string

Hyung-Hwan Kim

http://www.w3.org/2001/XMLSchema#string

Jeong Hyun Lee

http://www.w3.org/2001/XMLSchema#string

Karen L Furie

http://www.w3.org/2001/XMLSchema#string

Masha V Poyurovsky

http://www.w3.org/2001/XMLSchema#string

P2860

Rocks: multifunctional kinases in cell behaviour

Comparative gene expression profiling in three primary human cell lines after treatment with a novel inhibitor of Rho kinase or atorvastatin

The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton

ROCKs as immunomodulators of stroke

The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase

ROCK-I and ROCK-II, two isoforms of Rho-associated coiled-coil forming protein serine/threonine kinase in mice

Synthesis and antiviral activity of 5- and 5'-substituted thymidine analogs

Activation of G12/G13 results in shape change and Rho/Rho-kinase-mediated myosin light chain phosphorylation in mouse platelets

Improving bioscience research reporting: the ARRIVE guidelines for reporting animal research

Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho

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2-14

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scholarly article

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1517758

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10.1002/ACN3.19

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1

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1

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Daniel von Bornstadt

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2014-01-01T00:00:00Z

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P5875

259920595

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24466563

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P921

cerebral infarction

P932

3900310

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