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A whole-cell computational model predicts phenotype from genotype

A whole-cell computational model predicts phenotype from genotype

http://www.wikidata.org/entity/Q24622101

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The evolution of genome-scale models of cancer metabolism A multi-level multi-scale approach to study essential genes in Mycobacterium tuberculosis Genome-scale engineering for systems and synthetic biology CeCaFDB: a curated database for the documentation, visualization and comparative analysis of central carbon metabolic flux distributions explored by 13C-fluxomics Potentials of single-cell biology in identification and validation of disease biomarkers Constraint Based Modeling Going Multicellular Personalized Cardiovascular Disease Prediction and Treatment-A Review of Existing Strategies and Novel Systems Medicine Tools Synthetic Ecology of Microbes: Mathematical Models and Applications Integration of 'omics' data in aging research: from biomarkers to systems biology From cultured to uncultured genome sequences: metagenomics and modeling microbial ecosystems Bridging Systems Medicine and Patient Needs Mathematical models light up plant signaling Computational approaches for understanding energy metabolism Merging molecular mechanism and evolution: theory and computation at the interface of biophysics and evolutionary population genetics The role of single-cell analyses in understanding cell lineage commitment Reverse engineering and identification in systems biology: strategies, perspectives and challenges A Computational Framework for Bioimaging Simulation Cell-based screening: extracting meaning from complex data.Genomic location of the major ribosomal protein gene locus determines Vibrio cholerae global growth and infectivity Design and synthesis of a minimal bacterial genome A perspective on bridging scales and design of models using low-dimensional manifolds and data-driven model inference The Evolution of Per-cell Organelle Number Computing the functional proteome: recent progress and future prospects for genome-scale models Analysis of genetic variation and potential applications in genome-scale metabolic modeling Quantitative and logic modelling of molecular and gene networks Data-driven integration of genome-scale regulatory and metabolic network models Enhancing the discovery and development of immunotherapies for cancer using quantitative and systems pharmacology: Interleukin-12 as a case study Using Genome-scale Models to Predict Biological Capabilities Computationally Modeling Lipid Metabolism and Aging: A Mini-review Biomolecular interactions modulate macromolecular structure and dynamics in atomistic model of a bacterial cytoplasm.Designing cell-targeted therapeutic proteins reveals the interplay between domain connectivity and cell binding A cell simulator platform: the cell collective Integration of biochemical and electrical signaling-multiscale model of the medium spiny neuron of the striatum Modeling integrated cellular machinery using hybrid Petri-Boolean networks Flux imbalance analysis and the sensitivity of cellular growth to changes in metabolite pools Metabolic constraint-based refinement of transcriptional regulatory networks Inactivation of metabolic genes causes short- and long-range dys-regulation in Escherichia coli metabolic network Systematic evaluation of methods for integration of transcriptomic data into constraint-based models of metabolism Towards structural systems pharmacology to study complex diseases and personalized medicine A model of proteostatic energy cost and its use in analysis of proteome trends and sequence evolution

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A whole-cell computational model predicts phenotype from genotype

http://www.wikidata.org/entity/Q24622101

description

2012 nî lūn-bûn

@nan

2012 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2012年の論文

@ja

2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

name

A whole-cell computational model predicts phenotype from genotype

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A whole-cell computational model predicts phenotype from genotype

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A whole-cell computational model predicts phenotype from genotype

@nl

type

label

A whole-cell computational model predicts phenotype from genotype

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A whole-cell computational model predicts phenotype from genotype

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A whole-cell computational model predicts phenotype from genotype

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prefLabel

A whole-cell computational model predicts phenotype from genotype

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A whole-cell computational model predicts phenotype from genotype

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A whole-cell computational model predicts phenotype from genotype

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A whole-cell computational model predicts phenotype from genotype

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Benjamin Bolival

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Derek N Macklin

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Jared M Jacobs

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Jayodita C Sanghvi

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John I Glass

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Jonathan R Karr

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Markus W Covert

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Miriam V Gutschow

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Nacyra Assad-Garcia

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P2860

The Minimal Gene Complement of Mycoplasma genitalium

Essential genes of a minimal bacterium.

The CyberCell Database (CCDB): a comprehensive, self-updating, relational database to coordinate and facilitate in silico modeling of Escherichia coli

A genomic regulatory network for development

Complete chemical synthesis, assembly, and cloning of a Mycoplasma genitalium genome

What is flux balance analysis?

The pyruvate dehydrogenase multi-enzyme complex from Gram-negative bacteria

Creation of a bacterial cell controlled by a chemically synthesized genome

A genome-scale metabolic reconstruction of Mycoplasma genitalium, iPS189

Genome-scale reconstruction of Escherichia coli's transcriptional and translational machinery: a knowledge base, its mathematical formulation, and its functional characterization

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389-401

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22817898

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5,6-dihydroxyuracil

2'-deoxyinosine-5'-monophosphate

5,6-dihydrothymidine

Deoxycytidine diphosphate

2-deoxy-D-glucose 6-phosphate

2,3-dipalmitoyl-S-glycerylcysteine

1,2-didodecanoyl-sn-glycero-3-cytidine 5'-diphosphate

5-carboxymethylaminomethyl-2-thiouridine

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