Gene knockout of Acc2 has little effect on body weight, fat mass, or food intake - Test2 - elhamkhani - TriplyDB

Gene knockout of Acc2 has little effect on body weight, fat mass, or food intake

Gene knockout of Acc2 has little effect on body weight, fat mass, or food intake

http://www.wikidata.org/entity/Q24622227

about

Pathway-selective insulin resistance and metabolic disease: the importance of nutrient flux The hepatic cannabinoid 1 receptor as a modulator of hepatic energy state and food intake Structure and function of biotin-dependent carboxylases Genetic inhibition of hepatic acetyl-CoA carboxylase activity increases liver fat and alters global protein acetylation.Genomic structural variations for cardiovascular and metabolic comorbidity The effect of ACACB cis-variants on gene expression and metabolic traits.Chemical-genetic induction of Malonyl-CoA decarboxylase in skeletal muscle.An ACACB variant implicated in diabetic nephropathy associates with body mass index and gene expression in obese subjects.Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin.Mitochondrial dysfunction and insulin resistance: an update.AMPK inhibition in health and disease.De novo lipogenesis in metabolic homeostasis: More friend than foe?Resveratrol compounds inhibit human holocarboxylase synthetase and cause a lean phenotype in Drosophila melanogaster Targeted chemical-genetic regulation of protein stability in vivo Acetyl-CoA carboxylase 2-/- mutant mice are protected against fatty liver under high-fat, high-carbohydrate dietary and de novo lipogenic conditions.Lipid-induced mitochondrial stress and insulin action in muscle In vivo, fatty acid translocase (CD36) critically regulates skeletal muscle fuel selection, exercise performance, and training-induced adaptation of fatty acid oxidation.Cardiac-specific deletion of acetyl CoA carboxylase 2 prevents metabolic remodeling during pressure-overload hypertrophy Detection of thermogenesis in rodents in response to anti-obesity drugs and genetic modification.Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats.Role of Dietary Fructose and Hepatic De Novo Lipogenesis in Fatty Liver Disease Inhibition of acetyl-CoA carboxylases by soraphen A prevents lipid accumulation and adipocyte differentiation in 3T3-L1 cells Minimal impact of age and housing temperature on the metabolic phenotype of Acc2-/- mice.Susceptibility of podocytes to palmitic acid is regulated by fatty acid oxidation and inversely depends on acetyl-CoA carboxylases 1 and 2.Diabetes area participation analysis: a review of companies and targets described in the 2008 - 2010 patent literature.Targeting AMPK for cardiac protection: opportunities and challenges.Regulation and limitations to fatty acid oxidation during exercise.Functional characterization of AMP-activated protein kinase signaling in tumorigenesis.Acetyl CoA carboxylase inactivation and meiotic maturation in mouse oocytes.Skeletal muscle ACC2 S212 phosphorylation is not required for the control of fatty acid oxidation during exercise.AMPKα2 deficiency uncovers time dependency in the regulation of contraction-induced palmitate and glucose uptake in mouse muscle.Skeletal muscle fat metabolism after exercise in humans: influence of fat availability.Nonalcoholic Fatty Liver Disease as a Nexus of Metabolic and Hepatic Diseases.Muscle expression of a malonyl-CoA-insensitive carnitine palmitoyltransferase-1 protects mice against high-fat/high-sucrose diet-induced insulin resistance.Biotin-dependent functions in adiposity: a study of monozygotic twin pairs.De Novo Fatty Acid Synthesis During Mycobacterial Infection Is a Prerequisite for the Function of Highly Proliferative T Cells, But Not for Dendritic Cells or Macrophages.Analysis of chromosomal structural variation in patients with congenital left-sided cardiac lesions.Acetyl CoA Carboxylase Inhibition Reduces Hepatic Steatosis but Elevates Plasma Triglycerides in Mice and Humans: A Bedside to Bench Investigation.Adiponectin prevents reduction of lipid-induced mitochondrial biogenesis via AMPK/ACC2 pathway in chicken adipocyte.AMPK phosphorylation of ACC2 is required for skeletal muscle fatty acid oxidation and insulin sensitivity in mice.

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P2860

Gene knockout of Acc2 has little effect on body weight, fat mass, or food intake

http://www.wikidata.org/entity/Q24622227

description

2010 nî lūn-bûn

@nan

2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի ապրիլին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Gene knockout of Acc2 has little effect on body weight, fat mass, or food intake

@ast

Gene knockout of Acc2 has little effect on body weight, fat mass, or food intake

@en

Gene knockout of Acc2 has little effect on body weight, fat mass, or food intake

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type

label

Gene knockout of Acc2 has little effect on body weight, fat mass, or food intake

@ast

Gene knockout of Acc2 has little effect on body weight, fat mass, or food intake

@en

Gene knockout of Acc2 has little effect on body weight, fat mass, or food intake

@nl

prefLabel

Gene knockout of Acc2 has little effect on body weight, fat mass, or food intake

@ast

Gene knockout of Acc2 has little effect on body weight, fat mass, or food intake

@en

Gene knockout of Acc2 has little effect on body weight, fat mass, or food intake

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PNAS.0913492107

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Gene knockout of Acc2 has little effect on body weight, fat mass, or food intake

@en

P2093

Bradford B Lowell

http://www.w3.org/2001/XMLSchema#string

David P Olson

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Gary W Cline

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Thomas Pulinilkunnil

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P2860

The subcellular localization of acetyl-CoA carboxylase 2

Requirement for serum response factor for skeletal muscle growth and maturation revealed by tissue-specific gene deletion in mice

AdPLA ablation increases lipolysis and prevents obesity induced by high-fat feeding or leptin deficiency

Acetyl-CoA carboxylase 2 mutant mice are protected against obesity and diabetes induced by high-fat/high-carbohydrate diets

Continuous fatty acid oxidation and reduced fat storage in mice lacking acetyl-CoA carboxylase 2

Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

Regulation of acetyl-CoA carboxylase

Glucose and fat metabolism in adipose tissue of acetyl-CoA carboxylase 2 knockout mice

Reduced heart size and increased myocardial fuel substrate oxidation in ACC2 mutant mice

Hepatic de novo lipogenesis is present in liver-specific ACC1-deficient mice

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7598-603

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scholarly article

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10.1073/PNAS.0913492107

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16

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107

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Gerald I. Shulman

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2010-04-20T00:00:00Z

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43023399

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20368432

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2867727

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