Schizophrenia susceptibility gene dysbindin regulates glutamatergic and dopaminergic functions via distinctive mechanisms in Drosophila
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Dopamine dynamics and signaling in Drosophila: an overview of genes, drugs and behavioral paradigmsMutations in the BLOC-1 subunits dysbindin and muted generate divergent and dosage-dependent phenotypes.Replication of association between schizophrenia and chromosome 6p21-6p22.1 polymorphisms in Chinese Han populationThe N-ethylmaleimide-sensitive factor and dysbindin interact to modulate synaptic plasticity.Neuronal copper homeostasis susceptibility by genetic defects in dysbindin, a schizophrenia susceptibility factor.Transient activation of dopaminergic neurons during development modulates visual responsiveness, locomotion and brain activity in a dopamine ontogeny model of schizophrenia.Increased dysbindin-1B isoform expression in schizophrenia and its propensity in aggresome formation.The Proteome of BLOC-1 Genetic Defects Identifies the Arp2/3 Actin Polymerization Complex to Function Downstream of the Schizophrenia Susceptibility Factor Dysbindin at the SynapseDysbindin Deficiency Modifies the Expression of GABA Neuron and Ion Permeation Transcripts in the Developing Hippocampus.The BLOC-1 Subunit Pallidin Facilitates Activity-Dependent Synaptic Vesicle Recycling.Neuroligins Nlg2 and Nlg4 Affect Social Behavior in Drosophila melanogaster.DISC1 causes associative memory and neurodevelopmental defects in fruit flies.Reduced expression of the dysbindin-like gene in the Bombyx mori ov mutant exhibiting mottled translucency of the larval skin.Functional characterization of dopamine transporter in vivo using Drosophila melanogaster behavioral assays.Neurodevelopmental disease mechanisms, primary cilia, and endosomes converge on the BLOC-1 and BORC complexes.Disrupted-in-Schizophrenia-1 (DISC1) protein disturbs neural function in multiple disease-risk pathways.Dysbindin gene variability is associated with cognitive abnormalities in first-episode non-affective psychosis.Dysbindin-1 modifies signaling and cellular localization of recombinant, human D₃ and D₂ receptors.The β-alanyl-monoamine synthase ebony is regulated by schizophrenia susceptibility gene dysbindin in Drosophila.
P2860
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P2860
Schizophrenia susceptibility gene dysbindin regulates glutamatergic and dopaminergic functions via distinctive mechanisms in Drosophila
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2011 nî lūn-bûn
@nan
2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Schizophrenia susceptibility g ...... ctive mechanisms in Drosophila
@ast
Schizophrenia susceptibility g ...... ctive mechanisms in Drosophila
@en
Schizophrenia susceptibility g ...... ctive mechanisms in Drosophila
@nl
type
label
Schizophrenia susceptibility g ...... ctive mechanisms in Drosophila
@ast
Schizophrenia susceptibility g ...... ctive mechanisms in Drosophila
@en
Schizophrenia susceptibility g ...... ctive mechanisms in Drosophila
@nl
prefLabel
Schizophrenia susceptibility g ...... ctive mechanisms in Drosophila
@ast
Schizophrenia susceptibility g ...... ctive mechanisms in Drosophila
@en
Schizophrenia susceptibility g ...... ctive mechanisms in Drosophila
@nl
P2093
P2860
P50
P921
P356
P1476
Schizophrenia susceptibility g ...... ctive mechanisms in Drosophila
@en
P2093
Lianzhang Wang
Shanxi Feng
Yichun Shuai
P2860
P304
18831-18836
P356
10.1073/PNAS.1114569108
P407
P577
2011-11-02T00:00:00Z