Neuronal stimulation with 5-hydroxytryptamine 4 receptor induces anti-inflammatory actions via α7nACh receptors on muscularis macrophages associated with postoperative ileus - Test2 - elhamkhani - TriplyDB

Neuronal stimulation with 5-hydroxytryptamine 4 receptor induces anti-inflammatory actions via α7nACh receptors on muscularis macrophages associated with postoperative ileus

Neuronal stimulation with 5-hydroxytryptamine 4 receptor induces anti-inflammatory actions via α7nACh receptors on muscularis macrophages associated with postoperative ileus

http://www.wikidata.org/entity/Q24625795

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Serotonin augments gut pacemaker activity via 5-HT3 receptors The vagus nerve in appetite regulation, mood and intestinal inflammation Neuro-anatomical evidence indicating indirect modulation of macrophages by vagal efferents in the intestine but not in the spleen Daikenchuto, a traditional Japanese herbal medicine, ameliorates postoperative ileus by anti-inflammatory action through nicotinic acetylcholine receptors.Comparison of effects of a selective 5-HT reuptake inhibitor versus a 5-HT4 receptor agonist on in vivo neurogenesis at the rectal anastomosis in rats.Neural networks in intestinal immunoregulation Suppression of contractile activity in the small intestine by indomethacin and omeprazole.Understanding the Mysterious M2 Macrophage through Activation Markers and Effector Mechanisms.Interleukin-6 (IL-6) mediated the increased contraction of distal colon in streptozotocin-induced diabetes in rats via IL-6 receptor pathway The dual effect of cannabinoid receptor-1 deficiency on the murine postoperative ileus Early administration of RS 67333, a specific 5-HT4 receptor agonist, prevents amyloidogenesis and behavioral deficits in the 5XFAD mouse model of Alzheimer's disease.The 5-hydroxytryptamine 4 Receptor Agonist-induced Actions and Enteric Neurogenesis in the Gut.Neurogastroenterology in 2011: Emerging concepts in neurogastroenterology and motility.Immune mediators of postoperative ileus.New therapeutic strategies for postoperative ileus.Drug discovery approaches to irritable bowel syndrome.The Involvement of Parasympathetic and Sympathetic Nerve in the Inflammatory Reflex.Novel investigational drugs for constipation-predominant irritable bowel syndrome: a review.The intestinal cholinergic anti-inflammatory pathway.Resident macrophages in the healthy and inflamed intestinal muscularis externa.Alternative Anaphylactic Routes: The Potential Role of Macrophages The Effects of Serotonin in Immune Cells.Time-dependent changes in inhibitory action of lipopolysaccharide on intestinal motility in rat.Novel method for studying postoperative ileus in mice.Anti-emetic drug maropitant induces intestinal motility disorder but not anti-inflammatory action in mice.Postoperative Ileus: Pathophysiology, Current Therapeutic Approaches.Therapeutic action of 5-HT3 receptor antagonists targeting peritoneal macrophages in post-operative ileus.Randomised clinical trial: prucalopride, a colonic pro-motility agent, reduces the duration of post-operative ileus after elective gastrointestinal surgery.A distinct vagal anti-inflammatory pathway modulates intestinal muscularis resident macrophages independent of the spleen.The anti-inflammatory pathway regulated via nicotinic acetylcholine receptors in rat intestinal mesothelial cells.Serotonin drives the acquisition of a profibrotic and anti-inflammatory gene profile through the 5-HT7R-PKA signaling axis.YH12852, a potent and highly selective 5-HT4 receptor agonist, significantly improves both upper and lower gastrointestinal motility in a guinea pig model of postoperative ileus.The 5-HT3 Receptor Antagonist Ondansetron Attenuates Pancreatic Injury in Cerulein-Induced Acute Pancreatitis Model.Effect of jatrorrhizine on delayed gastrointestinal transit in rat postoperative ileus.Zingiberis Siccatum Rhizoma, the active component of the Kampo formula Daikenchuto, induces anti-inflammatory actions through α7 nicotinic acetylcholine receptor activation.Effect of 5-HT4 receptor agonist mosapride citrate on rectosigmoid sensorimotor function in patients with irritable bowel syndrome.

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Neuronal stimulation with 5-hydroxytryptamine 4 receptor induces anti-inflammatory actions via α7nACh receptors on muscularis macrophages associated with postoperative ileus

http://www.wikidata.org/entity/Q24625795

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Hiroshi Ozaki

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Masahiko Fujisawa

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Takahisa Murata

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Yasuyuki Seto

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Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation

5-hydroxytryptamine and the gastrointestinal tract: where next?

Nicotine inhibits Fc epsilon RI-induced cysteinyl leukotrienes and cytokine production without affecting mast cell degranulation through alpha 7/alpha 9/alpha 10-nicotinic receptors

Monocyte and macrophage heterogeneity

Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin

The effect of mosapride citrate on proximal and distal colonic motor function in the guinea-pig in vitro.

Postoperative ileus: a preventable event.

The serotonin signaling system: from basic understanding to drug development for functional GI disorders.

The 5-HT(4) agonists cisapride, mosapride, and CJ-033466, a Novel potent compound, exhibit different human ether-a-go-go-related gene (hERG)-blocking activities.

5-Amino-6-chloro-N-[(1-isobutylpiperidin-4-yl)methyl]-2-methylimidazo[1,2-alpha]pyridine-8-carboxamide (CJ-033,466), a novel and selective 5-hydroxytryptamine4 receptor partial agonist: pharmacological profile in vitro and gastroprokinetic effect in

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