The many roles of histone deacetylases in development and physiology: implications for disease and therapy - Test2 - elhamkhani - TriplyDB

The many roles of histone deacetylases in development and physiology: implications for disease and therapy

The many roles of histone deacetylases in development and physiology: implications for disease and therapy

http://www.wikidata.org/entity/Q24628821

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Essential role for miR-196a in brown adipogenesis of white fat progenitor cells Sirtuins: molecular traffic lights in the crossroad of oxidative stress, chromatin remodeling, and transcription Mice lacking α-tubulin acetyltransferase 1 are viable but display α-tubulin acetylation deficiency and dentate gyrus distortion Regulation of G6PD acetylation by SIRT2 and KAT9 modulates NADPH homeostasis and cell survival during oxidative stress HDAC3 is negatively regulated by the nuclear protein DBC1 Hdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cells A novel small molecule hydroxamate preferentially inhibits HDAC6 activity and tumour growth Histone deacetylase signaling in cardioprotection Hopx and Hdac2 interact to modulate Gata4 acetylation and embryonic cardiac myocyte proliferation Histone deacetylase (HDAC) inhibitors attenuate cardiac hypertrophy by suppressing autophagy Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis The AMPK signalling pathway coordinates cell growth, autophagy and metabolism Tasquinimod Is an Allosteric Modulator of HDAC4 survival signaling within the compromised cancer microenvironment Epigenetic control of skull morphogenesis by histone deacetylase 8 Epigenetics: a molecular link between environmental factors and type 2 diabetes Protein Kinase D1 Signaling in Angiogenic Gene Expression and VEGF-Mediated Angiogenesis Diagnostic workup and management of patients with suspected Niemann-Pick type C disease The SphKs/S1P/S1PR1 axis in immunity and cancer: more ore to be mined Epigenetic Mechanisms in Developmental Alcohol-Induced Neurobehavioral Deficits Inhibition of histone deacetylases in cancer therapy: lessons from leukaemia Tasquinimod in the treatment of castrate-resistant prostate cancer - current status and future prospects The Functional Analysis of Histone Acetyltransferase MOF in Tumorigenesis Epigenetic Research of Neurodegenerative Disorders Using Patient iPSC-Based Models Role of histone deacetylases in pancreas: Implications for pathogenesis and therapy Global histone post-translational modifications and cancer: Biomarkers for diagnosis, prognosis and treatment?Common stemness regulators of embryonic and cancer stem cells Histone acetylation: novel target for the treatment of acute lymphoblastic leukemia New insights into the epigenetic control of satellite cells Histone Deacetylases and Cardiometabolic Diseases Epigenetics: the missing link to understanding β-cell dysfunction in the pathogenesis of type 2 diabetes HDAC8 substrates: Histones and beyond Nutrition, epigenetics, and metabolic syndrome Epigenetic mechanisms underlying cardiac degeneration and regeneration Epigenetic mechanisms in cardiac development and disease KATs in cancer: functions and therapies Creating a "Prosurvival Phenotype" Through Histone Deacetylase Inhibition: Past, Present, and Future Metabolic reprogramming by class I and II histone deacetylases Diverse roles of SIRT1 in cancer biology and lipid metabolism Regulation of chromatin structure in the cardiovascular system Clinical applications of epigenetics in cardiovascular disease: the long road ahead

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The many roles of histone deacetylases in development and physiology: implications for disease and therapy

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2009 nî lūn-bûn

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Nature Reviews Genetics

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Eric N Olson

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Michael Haberland

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Rusty L Montgomery

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Histone deacetylase inhibition modulates indoleamine 2,3-dioxygenase–dependent DC functions and regulates experimental graft-versus-host disease in mice

Regulation of skeletal myogenesis by association of the MEF2 transcription factor with class II histone deacetylases

Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation

Molecular cloning and characterization of a novel histone deacetylase HDAC10

Isolation and characterization of a novel class II histone deacetylase, HDAC10

Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR

CaM kinase II selectively signals to histone deacetylase 4 during cardiomyocyte hypertrophy

Cloning and functional characterization of HDAC11, a novel member of the human histone deacetylase family

Acetylation-dependent signal transduction for type I interferon receptor

HDAC6 is a microtubule-associated deacetylase

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