Robust chromosomal DNA repair via alternative end-joining in the absence of X-ray repair cross-complementing protein 1 (XRCC1)
about
Alternative end-joining mechanisms: a historical perspectiveFunctional redundancy between the XLF and DNA-PKcs DNA repair factors in V(D)J recombination and nonhomologous DNA end joiningDNA double-strand-break complexity levels and their possible contributions to the probability for error-prone processing and repair pathway choiceDNA ligases I and III cooperate in alternative non-homologous end-joining in vertebratesMechanism of suppression of chromosomal instability by DNA polymerase POLQMicrohomology-mediated end joining is activated in irradiated human cells due to phosphorylation-dependent formation of the XRCC1 repair complex.Generation and repair of AID-initiated DNA lesions in B lymphocytes.Requirement for Parp-1 and DNA ligases 1 or 3 but not of Xrcc1 in chromosomal translocation formation by backup end joining.Regulation of immunoglobulin class-switch recombination: choreography of noncoding transcription, targeted DNA deamination, and long-range DNA repair.Pathway choice in DNA double strand break repair: observations of a balancing act.Structure and function of the DNA ligases encoded by the mammalian LIG3 gene.DNA ligases as therapeutic targetsDNA repair mechanisms in dividing and non-dividing cells.Saccharomyces cerevisiae DNA ligase IV supports imprecise end joining independently of its catalytic activity.Akt-mediated phosphorylation of XLF impairs non-homologous end-joining DNA repair.Chromosomal translocations in human cells are generated by canonical nonhomologous end-joining.Identification of novel radiosensitizers in a high-throughput, cell-based screen for DSB repair inhibitors.Parp3 negatively regulates immunoglobulin class switch recombination.Telomere fusion threshold identifies a poor prognostic subset of breast cancer patients.X-ray repair cross-complementing protein 1 (XRCC1) deficiency enhances class switch recombination and is permissive for alternative end joining.DNA ligase I is not essential for mammalian cell viability.Immunoglobulin class-switch DNA recombination: induction, targeting and beyond.Ligase I and ligase III mediate the DNA double-strand break ligation in alternative end-joining.PARP1 is required for chromosomal translocations.PAXX and XLF DNA repair factors are functionally redundant in joining DNA breaks in a G1-arrested progenitor B-cell line.The role of activation-induced deaminase in antibody diversification and genomic instability.Repair of double-strand breaks by end joining.DNA double-strand break repair as determinant of cellular radiosensitivity to killing and target in radiation therapy.End-joining, translocations and cancer.Non-homologous end joining often uses microhomology: implications for alternative end joining.Functional overlaps between XLF and the ATM-dependent DNA double strand break response.Chromatin remodeller SMARCA4 recruits topoisomerase 1 and suppresses transcription-associated genomic instabilityDNA double-strand breaks and telomeres play important roles in trypanosoma brucei antigenic variation.Control of alternative end joining by the chromatin remodeler p400 ATPase.DNA Ligases I and III Support Nucleotide Excision Repair in DT40 Cells with Similar Efficiency.Development of an assay to measure mutagenic non-homologous end-joining repair activity in mammalian cells.The DNA Ligase IV Syndrome R278H Mutation Impairs B Lymphopoiesis via Error-Prone Nonhomologous End-Joining.DNA ligase C1 mediates the LigD-independent nonhomologous end-joining pathway of Mycobacterium smegmatis.Quantifying DNA double-strand breaks induced by site-specific endonucleases in living cells by ligation-mediated purification.Depletion of recombination-specific cofactors by the C-terminal mutant of the activation-induced cytidine deaminase causes the dominant negative effect on class switch recombination.
P2860
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P2860
Robust chromosomal DNA repair via alternative end-joining in the absence of X-ray repair cross-complementing protein 1 (XRCC1)
description
2012 nî lūn-bûn
@nan
2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Robust chromosomal DNA repair ...... omplementing protein 1 (XRCC1)
@ast
Robust chromosomal DNA repair ...... omplementing protein 1 (XRCC1)
@en
Robust chromosomal DNA repair ...... omplementing protein 1 (XRCC1)
@nl
type
label
Robust chromosomal DNA repair ...... omplementing protein 1 (XRCC1)
@ast
Robust chromosomal DNA repair ...... omplementing protein 1 (XRCC1)
@en
Robust chromosomal DNA repair ...... omplementing protein 1 (XRCC1)
@nl
prefLabel
Robust chromosomal DNA repair ...... omplementing protein 1 (XRCC1)
@ast
Robust chromosomal DNA repair ...... omplementing protein 1 (XRCC1)
@en
Robust chromosomal DNA repair ...... omplementing protein 1 (XRCC1)
@nl
P2093
P2860
P356
P1476
Robust chromosomal DNA repair ...... omplementing protein 1 (XRCC1)
@en
P2093
Bjoern Schwer
Cheng-Sheng Lee
Cristian Boboila
Frederick W Alt
Jing H Wang
Liz-Marie Albertorio Saez
Mila Jankovic
Monica Gostissa
Peter J McKinnon
P2860
P304
P356
10.1073/PNAS.1121470109
P407
P577
2012-02-14T00:00:00Z