Catalytic promiscuity in the biosynthesis of cyclic peptide secondary metabolites in planktonic marine cyanobacteria - Test2 - elhamkhani - TriplyDB

Catalytic promiscuity in the biosynthesis of cyclic peptide secondary metabolites in planktonic marine cyanobacteria

Catalytic promiscuity in the biosynthesis of cyclic peptide secondary metabolites in planktonic marine cyanobacteria

http://www.wikidata.org/entity/Q24630550

about

Evolution of lanthipeptide synthetases Recent application of metagenomic approaches toward the discovery of antimicrobials and other bioactive small molecules Cyclisation mechanisms in the biosynthesis of ribosomally synthesised and post-translationally modified peptides Tiny Microbes with a Big Impact: The Role of Cyanobacteria and Their Metabolites in Shaping Our Future Lanthipeptides: chemical synthesis versus in vivo biosynthesis as tools for pharmaceutical production Targeted metagenomics as a tool to tap into marine natural product diversity for the discovery and production of drug candidates Lessons from the past and charting the future of marine natural products drug discovery and chemical biology Lessons learned from the transformation of natural product discovery to a genome-driven endeavor Substrate Specificity of the Lanthipeptide Peptidase ElxP and the Oxidoreductase ElxO Variation in tropical reef symbiont metagenomes defined by secondary metabolism Antitumor activity of hierridin B, a cyanobacterial secondary metabolite found in both filamentous and unicellular marine strains Catalytic DNA with phosphatase activity Genome mining demonstrates the widespread occurrence of gene clusters encoding bacteriocins in cyanobacteria.A tribute to disorder in the genome of the bloom-forming freshwater cyanobacterium Microcystis aeruginosa Expansion of ribosomally produced natural products: a nitrile hydratase- and Nif11-related precursor family The hidden diversity of ribosomal peptide natural products.Production of lantipeptides in Escherichia coli.In silico analysis highlights the frequency and diversity of type 1 lantibiotic gene clusters in genome sequenced bacteria.Evolutionary radiation of lanthipeptides in marine cyanobacteria.Mechanistic studies on the substrate-tolerant lanthipeptide synthetase ProcM Bacterial display and screening of posttranslationally thioether-stabilized peptides.Structural investigation of ribosomally synthesized natural products by hypothetical structure enumeration and evaluation using tandem MS.Genome mining for ribosomally synthesized natural products Thiazole/oxazole-modified microcins: complex natural products from ribosomal templates Linking chemistry and genetics in the growing cyanobactin natural products family Lantibiotics from Geobacillus thermodenitrificans.ApnI, a transmembrane protein responsible for subtilomycin immunity, unveils a novel model for lantibiotic immunity.Structural characterization of four prochlorosins: a novel class of lantipeptides produced by planktonic marine cyanobacteria Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature.Improving the coverage of the cyanobacterial phylum using diversity-driven genome sequencing.Genome-derived insights into the biology of the hepatotoxic bloom-forming cyanobacterium Anabaena sp. strain 90 High divergence of the precursor peptides in combinatorial lanthipeptide biosynthesis.Insights into the physiology and ecology of the brackish-water-adapted Cyanobacterium Nodularia spumigena CCY9414 based on a genome-transcriptome analysis Substrate control in stereoselective lanthionine biosynthesis.A price to pay for relaxed substrate specificity: a comparative kinetic analysis of the class II lanthipeptide synthetases ProcM and HalM2.Novel LanT associated lantibiotic clusters identified by genome database mining.Response of Prochlorococcus ecotypes to co-culture with diverse marine bacteria Nine post-translational modifications during the biosynthesis of cinnamycin.Recognition sequences and substrate evolution in cyanobactin biosynthesis Pseudomycoicidin, a Class II Lantibiotic from Bacillus pseudomycoides.

P2860

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P2860

Catalytic promiscuity in the biosynthesis of cyclic peptide secondary metabolites in planktonic marine cyanobacteria

http://www.wikidata.org/entity/Q24630550

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2010 nî lūn-bûn

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2010 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2010 թվականի հունիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年论文

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PNAS.0913677107

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Proceedings of the National Academy of Sciences of the United States of America

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Catalytic promiscuity in the b ...... lanktonic marine cyanobacteria

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Daniel Sher

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Doug Rusch

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Ike Joewono

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Katherine Huang

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Libusha Kelly

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Patrick J Knerr

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P2860

The Sorcerer II Global Ocean Sampling expedition: northwest Atlantic through eastern tropical Pacific

Discovery of unique lanthionine synthetases reveals new mechanistic and evolutionary insights

Genome divergence in two Prochlorococcus ecotypes reflects oceanic niche differentiation

Patellamide A and C biosynthesis by a microcin-like pathway in Prochloron didemni, the cyanobacterial symbiont of Lissoclinum patella

Synergy and contingency as driving forces for the evolution of multiple secondary metabolite production by Streptomyces species

Gene family encoding the major toxins of lethal Amanita mushrooms

Enzymatic synthesis of cyclic triterpenes

Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)

Phosphate acquisition genes in Prochlorococcus ecotypes: evidence for genome-wide adaptation

Lacticin 481: in vitro reconstitution of lantibiotic synthetase activity.

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10430-5

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1003893

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10.1073/PNAS.0913677107

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Wilfred A van der Donk

Sallie W. Chisholm

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44608274

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20479271

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I-phytoplankton

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