Large-scale mapping of branchpoints in human pre-mRNA transcripts in vivo - Test2 - elhamkhani - TriplyDB

Large-scale mapping of branchpoints in human pre-mRNA transcripts in vivo

Large-scale mapping of branchpoints in human pre-mRNA transcripts in vivo

http://www.wikidata.org/entity/Q24630818

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RNA-Binding Proteins: Splicing Factors and Disease Clinical significance of intronic variants in BRAF inhibitor resistant melanomas with altered BRAF transcript splicing.Multiplexed and programmable regulation of gene networks with an integrated RNA and CRISPR/Cas toolkit in human cells.Lariat intronic RNAs in the cytoplasm of Xenopus tropicalis oocytes Genome-wide discovery of human splicing branchpoints Genome-wide study of mRNA degradation and transcript elongation in Escherichia coli.The RNA-binding protein QKI suppresses cancer-associated aberrant splicing.Correlated Evolution of Nucleotide Positions within Splice Sites in Mammals.Sequencing of lariat termini in S. cerevisiae reveals 5' splice sites, branch points, and novel splicing events The CYP2C19 Intron 2 Branch Point SNP is the Ancestral Polymorphism Contributing to the Poor Metabolizer Phenotype in Livers with CYP2C19*35 and CYP2C19*2 Alleles.Genome-wide identification of zero nucleotide recursive splicing in Drosophila.Vemurafenib-resistant BRAF selects alternative branch points different from its wild-type BRAF in intron 8 for RNA splicing.Widespread alternative and aberrant splicing revealed by lariat sequencing Lariat sequencing in a unicellular yeast identifies regulated alternative splicing of exons that are evolutionarily conserved with humans.DNA sequencing methods in human genetics and disease research.Pressure-overload cardiac hypertrophy is associated with distinct alternative splicing due to altered expression of splicing factors.Alternative splicing of U2AF1 reveals a shared repression mechanism for duplicated exons.The RNA-binding landscape of RBM10 and its role in alternative splicing regulation in models of mouse early development.Lives that introns lead after splicing.Transcriptomic Characterization of SF3B1 Mutation Reveals Its Pleiotropic Effects in Chronic Lymphocytic Leukemia.SF1 Phosphorylation Enhances Specific Binding to U2AF65 and Reduces Binding to 3'-Splice-Site RNA.IntSplice: prediction of the splicing consequences of intronic single-nucleotide variations in the human genome.Pathogenic variants that alter protein code often disrupt splicing.Structural toggle in the RNaseH domain of Prp8 helps balance splicing fidelity and catalytic efficiency.Large-scale analysis of branchpoint usage across species and cell lines.High-Throughput Assays to Assess the Functional Impact of Genetic Variants: A Road Towards Genomic-Driven Medicine.Identification of U2AF(35)-dependent exons by RNA-Seq reveals a link between 3' splice-site organization and activity of U2AF-related proteins.A Method to Predict the Structure and Stability of RNA/RNA Complexes.Identification of new branch points and unconventional introns in Saccharomyces cerevisiae.LaSSO, a strategy for genome-wide mapping of intronic lariats and branch points using RNA-seq.Splicing of many human genes involves sites embedded within introns.A heuristic model for computational prediction of human branch point sequence.Identification of functional single nucleotide polymorphisms in the branchpoint site.Machine learning annotation of human branchpoints.Predicting human splicing branchpoints by combining sequence-derived features and multi-label learning methods.Defective splicing of the RB1 transcript is the dominant cause of retinoblastomas.Identification of common genetic variants controlling transcript isoform variation in human whole blood.Rules and tools to predict the splicing effects of exonic and intronic mutations.Most human introns are recognized via multiple and tissue-specific branchpoints.RNA Structure Design Improves Activity and Specificity of trans-Splicing-Triggered Cell Death in a Suicide Gene Therapy Approach.

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Large-scale mapping of branchpoints in human pre-mRNA transcripts in vivo

http://www.wikidata.org/entity/Q24630818

description

2012 nî lūn-bûn

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2012 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի հուլիսին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

Large-scale mapping of branchpoints in human pre-mRNA transcripts in vivo

@ast

Large-scale mapping of branchpoints in human pre-mRNA transcripts in vivo

@en

Large-scale mapping of branchpoints in human pre-mRNA transcripts in vivo

@nl

type

label

Large-scale mapping of branchpoints in human pre-mRNA transcripts in vivo

@ast

Large-scale mapping of branchpoints in human pre-mRNA transcripts in vivo

@en

Large-scale mapping of branchpoints in human pre-mRNA transcripts in vivo

@nl

prefLabel

Large-scale mapping of branchpoints in human pre-mRNA transcripts in vivo

@ast

Large-scale mapping of branchpoints in human pre-mRNA transcripts in vivo

@en

Large-scale mapping of branchpoints in human pre-mRNA transcripts in vivo

@nl

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Nature Structural & Molecular Biology

P1476

Large-scale mapping of branchpoints in human pre-mRNA transcripts in vivo

@en

P2093

Alec M DeSimone

http://www.w3.org/2001/XMLSchema#string

Janice S Shih

http://www.w3.org/2001/XMLSchema#string

Madeleine E Filloux

http://www.w3.org/2001/XMLSchema#string

P2860

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

An upstream AG determines whether a downstream AG is selected during catalytic step II of splicing

Sfold web server for statistical folding and rational design of nucleic acids

Early commitment of yeast pre-mRNA to the spliceosome pathway

iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution

An RNA code for the FOX2 splicing regulator revealed by mapping RNA-protein interactions in stem cells

TopHat: discovering splice junctions with RNA-Seq

Multiple sequence alignment with the Clustal series of programs

WebLogo: A Sequence Logo Generator

Genome-wide analysis of PTB-RNA interactions reveals a strategy used by the general splicing repressor to modulate exon inclusion or skipping

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P304

719-21

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scholarly article

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3863059

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10.1038/NSMB.2327

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7

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19

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William G Fairbrother

Allison J Taggart

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2012-07-01T00:00:00Z

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227172030

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1043225520

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P698

22705790

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structural biology

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3465671

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