A polymorphism, R653Q, in the trifunctional enzyme methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase/formyltetrahydrofolate synthetase is a maternal genetic risk factor for neural tube defects: report of the Birth Defec

A polymorphism, R653Q, in the trifunctional enzyme methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase/formyltetrahydrofolate synthetase is a maternal genetic risk factor for neural tube defects: report of the Birth Defec

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http://www.wikidata.org/entity/Q24632141

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Genetics of human neural tube defects Characterization and review of MTHFD1 deficiency: four new patients, cellular delineation and response to folic and folinic acid treatment Genetic variation of folate-mediated one-carbon transfer pathway predicts susceptibility to choline deficiency in humans.A common variant in MTHFD1L is associated with neural tube defects and mRNA splicing efficiency Choline: critical role during fetal development and dietary requirements in adults Epigenetic mechanisms for nutrition determinants of later health outcomes Genetic variants in phosphatidylethanolamine N-methyltransferase and methylenetetrahydrofolate dehydrogenase influence biomarkers of choline metabolism when folate intake is restricted Association studies for asthma and atopic diseases: a comprehensive review of the literature Choline: clinical nutrigenetic/nutrigenomic approaches for identification of functions and dietary requirements Reduced MTHFD1 activity in male mice perturbs folate- and choline-dependent one-carbon metabolism as well as transsulfuration Dietary and genetic manipulations of folate metabolism differentially affect neocortical functions in mice.Neural tube defects: recent advances, unsolved questions, and controversies.Genetic and epigenetic contributions to human nutrition and health: managing genome-diet interactions.Genetic and lifestyle variables associated with homocysteine concentrations and the distribution of folate derivatives in healthy premenopausal women.Association between MTHFD1 G1958A polymorphism and neural tube defects susceptibility: a meta-analysis.Transcobalamin II receptor polymorphisms are associated with increased risk for neural tube defects.Lack of association between folate-receptor autoantibodies and neural-tube defects.Maternal choline concentrations during pregnancy and choline-related genetic variants as risk factors for neural tube defects.Evaluation of common genetic variants in 82 candidate genes as risk factors for neural tube defects.Methionine synthase polymorphisms (MTR 2756 A>G and MTR 2758 C>G) frequencies and distribution in the Jordanian population and their correlation with neural tube defects in the population of the northern part of Jordan Methylenetetrahydrofolate dehydrogenase (MTHFD) enzyme polymorphism as a maternal risk factor for trisomy 21: a clinical study The need for clinical decision support integrated with the electronic health record for the clinical application of whole genome sequencing information.Mthfd1 is a modifier of chemically induced intestinal carcinogenesis.Epidemiologic and genetic aspects of spina bifida and other neural tube defects.Significant association of MTHFD1 1958G>A single nucleotide polymorphism with nonsyndromic cleft lip and palate in Indian population Exploring the larval transcriptome of the common sole (Solea solea L.).Choline: clinical nutrigenetic/nutrigenomic approaches for identification of functions and dietary requirements.Lack of association between MTHFD1 G401A polymorphism and ovarian cancer susceptibility.Replication and exploratory analysis of 24 candidate risk polymorphisms for neural tube defects.Insights into metabolic mechanisms underlying folate-responsive neural tube defects: a minireview.Neural tube defects between folate metabolism and genetics.Pharmacogenetic determinants of outcome in acute lymphoblastic leukaemia.Maternal Mthfd1 disruption impairs fetal growth but does not cause neural tube defects in mice MTHFD1 gene polymorphisms as risk factors involved in orofacial cleft: an independent case-control study and a meta-analysis.Identifying women who might benefit from higher doses of folic acid in pregnancy.Pharmacogenetics of methotrexate.Polymorphisms in maternal folate pathway genes interact with arsenic in drinking water to influence risk of myelomeningocele Polymorphisms in MTHFD1 Gene and Susceptibility to Neural Tube Defects: A Case-Control Study in a Chinese Han Population with Relatively Low Folate Levels The Genome Health Clinic and Genome Health Nutrigenomics concepts: diagnosis and nutritional treatment of genome and epigenome damage on an individual basis.Proteomic Analysis of One-carbon Metabolism-related Marker in Liver of Rat Offspring.

P2860

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P2860

A polymorphism, R653Q, in the trifunctional enzyme methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase/formyltetrahydrofolate synthetase is a maternal genetic risk factor for neural tube defects: report of the Birth Defec

Item

http://www.wikidata.org/entity/Q24632141

description

2002 nî lūn-bûn

@nan

2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2002年の論文

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2002年論文

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2002年論文

@zh-hant

2002年論文

@zh-hk

2002年論文

@zh-mo

2002年論文

@zh-tw

2002年论文

@wuu

name

A polymorphism, R653Q, in the ...... cts: report of the Birth Defec

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type

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label

A polymorphism, R653Q, in the ...... cts: report of the Birth Defec

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A polymorphism, R653Q, in the ...... cts: report of the Birth Defec

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P1476

A polymorphism, R653Q, in the ...... e Birth Defects Research Group

@en

P2093

Anne Parle-McDermott

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Christopher Cox

http://www.w3.org/2001/XMLSchema#string

Deborah A Swanson

http://www.w3.org/2001/XMLSchema#string

John M Scott

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Lawrence C Brody

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Mary Conley

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Mary P McKeever

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Peadar N Kirke

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Valerie B O'Leary

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P2860

A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase

The "thermolabile" variant of methylenetetrahydrofolate reductase and neural tube defects: An evaluation of genetic risk and the relative importance of the genotypes of the embryo and the mother.

Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM)

Metabolic role of cytoplasmic isozymes of 5,10-methylenetetrahydrofolate dehydrogenase in Saccharomyces cerevisiae.

Primary structure of a human trifunctional enzyme. Isolation of a cDNA encoding methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase-formyltetrahydrofolate synthetase

Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. MRC Vitamin Study Research Group

Molecular genetic analysis of the gene encoding the trifunctional enzyme MTHFD (methylenetetrahydrofolate-dehydrogenase, methenyltetrahydrofolate-cyclohydrolase, formyltetrahydrofolate synthetase) in patients with neural tube defects

Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation

A log-linear approach to case-parent-triad data: assessing effects of disease genes that act either directly or through maternal effects and that may be subject to parental imprinting.

A pseudogene on the X chromosome for the human trifunctional enzyme MTHFD (methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase-formyltetrahydrofolate synthetase).

P304

1207-15

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scholarly article

case report

P356

10.1086/344213

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English

P433

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P478

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James L. Mills

Anne M Molloy

P577

2002-11-01T00:00:00Z

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11076111

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12384833

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risk factor

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385099

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A polymorphism, R653Q, in the trifunctional enzyme methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase/formyltetrahydrofolate synthetase is a maternal genetic risk factor for neural tube defects: report of the Birth Defec

about

P2860

P2860

A polymorphism, R653Q, in the trifunctional enzyme methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase/formyltetrahydrofolate synthetase is a maternal genetic risk factor for neural tube defects: report of the Birth Defec

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