Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease - Test2 - elhamkhani - TriplyDB

Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease

Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease

http://www.wikidata.org/entity/Q24632904

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Association between Parkinson's Disease and Cigarette Smoking, Rural Living, Well-Water Consumption, Farming and Pesticide Use: Systematic Review and Meta-Analysis Catecholamine autotoxicity. Implications for pharmacology and therapeutics of Parkinson disease and related disorders Aldehyde Dehydrogenase 1 making molecular inroads into the differential vulnerability of nigrostriatal dopaminergic neuron subtypes in Parkinson's disease Aldehyde dehydrogenase inhibition generates a reactive dopamine metabolite autotoxic to dopamine neurons Organochlorine chemicals and neurodegeneration among elderly subjects in Costa Rica PACAP deficiency sensitizes nigrostriatal dopaminergic neurons to paraquat-induced damage and modulates central and peripheral inflammatory activation in mice Endogenous methanol regulates mammalian gene activity Neurotoxicity of the Parkinson Disease-Associated Pesticide Ziram Is Synuclein-Dependent in Zebrafish Embryos Aldehyde dehydrogenase 1 defines and protects a nigrostriatal dopaminergic neuron subpopulation Determinants of buildup of the toxic dopamine metabolite DOPAL in Parkinson's disease.Benomyl, aldehyde dehydrogenase, DOPAL, and the catecholaldehyde hypothesis for the pathogenesis of Parkinson's disease.Donor CD4+ Foxp3+ regulatory T cells are necessary for posttransplantation cyclophosphamide-mediated protection against GVHD in mice.Targeting aldehyde dehydrogenase 2: new therapeutic opportunities.Defining midbrain dopaminergic neuron diversity by single-cell gene expression profiling.Synergistic effects on dopamine cell death in a Drosophila model of chronic toxin exposure.Involvement of the sodium-calcium exchanger 3 (NCX3) in ziram-induced calcium dysregulation and toxicity.Ocular irritation from product of pesticide degradation among workers in a seed warehouse.Rotenone decreases intracellular aldehyde dehydrogenase activity: implications for the pathogenesis of Parkinson's disease.Methylmercury impairs canonical dopamine metabolism in rat undifferentiated pheochromocytoma (PC12) cells by indirect inhibition of aldehyde dehydrogenase.Neuroprotective effects of aldehyde dehydrogenase 2 activation in rotenone-induced cellular and animal models of parkinsonism Emerging Toxicity Models from Emerging Scientists.Platelet mitochondrial activity and pesticide exposure in early Parkinson's disease Oligomerization and Membrane-binding Properties of Covalent Adducts Formed by the Interaction of α-Synuclein with the Toxic Dopamine Metabolite 3,4-Dihydroxyphenylacetaldehyde (DOPAL).Molecular heterogeneity of midbrain dopaminergic neurons--Moving toward single cell resolution.Mitochondrial dysfunction and cell death in neurodegenerative diseases through nitroxidative stress Aldehyde dehydrogenase 2 is associated with cognitive functions in patients with Parkinson's disease Pesticides that inhibit the ubiquitin-proteasome system: effect measure modification by genetic variation in SKP1 in Parkinson׳s disease.Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration.Aldehyde dehydrogenase variation enhances effect of pesticides associated with Parkinson disease.DOPAL derived alpha-synuclein oligomers impair synaptic vesicles physiological function.Targeting midkine and pleiotrophin signalling pathways in addiction and neurodegenerative disorders: recent progress and perspectives.New insight into neurodegeneration: the role of proteomics.Molecular mechanisms of dopaminergic subset specification: fundamental aspects and clinical perspectives.Aldehyde dehydrogenase (ALDH) in Alzheimer's and Parkinson's disease.Molecular determinants of selective dopaminergic vulnerability in Parkinson's disease: an update.Of Pesticides and Men: a California Story of Genes and Environment in Parkinson's Disease.Metabolic Dysfunction in Parkinson's Disease: Bioenergetics, Redox Homeostasis and Central Carbon Metabolism.Linking Stress, Catecholamine Autotoxicity, and Allostatic Load with Neurodegenerative Diseases: A Focused Review in Memory of Richard Kvetnansky.Genome-wide Analysis of RARβ Transcriptional Targets in Mouse Striatum Links Retinoic Acid Signaling with Huntington's Disease and Other Neurodegenerative Disorders.Base excision repair variants and pesticide exposure increase Parkinson's disease risk.

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P2860

Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease

http://www.wikidata.org/entity/Q24632904

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2013 nî lūn-bûn

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2013 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2013年の論文

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2013年論文

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2013年論文

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2013年论文

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Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease

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Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease

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Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease

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Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease

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Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease

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Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease

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Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease

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Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease

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Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease

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Proceedings of the National Academy of Sciences of the United States of America

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Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease

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Aaron Lulla

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Alvaro Sagasti

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Arthur G Fitzmaurice

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Hoa A Lam

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Jeff M Bronstein

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John E Casida

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Kelley C O'Donnell

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Lisa Barnhill

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Mark C Stahl

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Myles Cockburn

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P2860

Rotenone, paraquat, and Parkinson's disease

Plantation work and risk of Parkinson disease in a population-based longitudinal study

Pesticide/environmental exposures and Parkinson's disease in East Texas

Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies

Solvent exposures and Parkinson disease risk in twins

Mechanisms of rotenone-induced proteasome inhibition

Historical pesticide exposure in California using pesticide use reports and land-use surveys: an assessment of misclassification error and bias.

The subcellular distribution and properties of aldehyde dehydrogenases in rat liver

Impairment of the ubiquitin-proteasome system by protein aggregation

Ageing and Parkinson's disease: substantia nigra regional selectivity

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23267077

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Parkinson's disease

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