Matricellular protein CCN1 activates a proinflammatory genetic program in murine macrophages - Test2 - elhamkhani - TriplyDB

Matricellular protein CCN1 activates a proinflammatory genetic program in murine macrophages

Matricellular protein CCN1 activates a proinflammatory genetic program in murine macrophages

http://www.wikidata.org/entity/Q24633369

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The matricellular protein cysteine-rich protein 61 (CCN1/Cyr61) enhances physiological adaptation of retinal vessels and reduces pathological neovascularization associated with ischemic retinopathy Cell surface receptors for CCN proteins CCN: core regulatory proteins in the microenvironment that affect the metastasis of hepatocellular carcinoma?Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets CCN4 regulates vascular smooth muscle cell migration and proliferation Elevated OPN, IP-10, and neutrophilia in loop-mediated isothermal amplification confirmed tuberculosis patients.CCN1/CYR61-mediated meticulous patrolling by Ly6Clow monocytes fuels vascular inflammation S. aureus blocks efferocytosis of neutrophils by macrophages through the activity of its virulence factor alpha toxin.Enhancement of CCL2 expression and monocyte migration by CCN1 in osteoblasts through inhibiting miR-518a-5p: implication of rheumatoid arthritis therapy.Interplay between CCN1 and Wnt5a in endothelial cells and pericytes determines the angiogenic outcome in a model of ischemic retinopathy.CCN1/CYR61: the very model of a modern matricellular protein.Leptin induces oncostatin M production in osteoblasts by downregulating miR-93 through the Akt signaling pathway.Cysteine-rich protein 61 plays a proinflammatory role in obstructive kidney fibrosis.Matrix protein CCN1 induced by bacterial DNA and CpG ODN limits lung inflammation and contributes to innate immune homeostasis Retinoids suppress cysteine-rich protein 61 (CCN1), a negative regulator of collagen homeostasis, in skin equivalent cultures and aged human skin in vivo.CCN1 contributes to skin connective tissue aging by inducing age-associated secretory phenotype in human skin dermal fibroblasts.Cyr61 promotes CD204 expression and the migration of macrophages via MEK/ERK pathway in esophageal squamous cell carcinoma.CCN1 induces oncostatin M production in osteoblasts via integrin-dependent signal pathways CYR61 (CCN1) overexpression induces lung injury in mice Matricellular proteins in cardiac adaptation and disease.Role of cysteine-rich 61 protein (CCN1) in macrophage-mediated oncolytic herpes simplex virus clearance.Application of Comparative Transcriptional Genomics to Identify Molecular Targets for Pediatric IBD.CCN1 induces hepatic ductular reaction through integrin αvβ₅-mediated activation of NF-κB.The matricellular protein CCN1 mediates neutrophil efferocytosis in cutaneous wound healing Role of Age-Associated Alterations of the Dermal Extracellular Matrix Microenvironment in Human Skin Aging: A Mini-Review.The matricellular protein CCN1 promotes mucosal healing in murine colitis through IL-6.Serum Cyr61 is associated with clinical disease activity and inflammation in patients with systemic lupus erythematosus.Single and Compound Knock-outs of MicroRNA (miRNA)-155 and Its Angiogenic Gene Target CCN1 in Mice Alter Vascular and Neovascular Growth in the Retina via Resident Microglia CCN1 expression in hepatocytes contributes to macrophage infiltration in nonalcoholic fatty liver disease in mice New Insights into the Function of the Matricellular CCN1: an Emerging Target in Proliferative Retinopathies.Hepatic and serum lipid signatures specific to nonalcoholic steatohepatitis in murine models.Elevated cysteine-rich protein 61 (CCN1) promotes skin aging via upregulation of IL-1β in chronically sun-exposed human skin The CCN family proteins: modulators of bone development and novel targets in bone-associated tumors Altered macrophage phenotype transition impairs skeletal muscle regeneration CCN1 promotes IL-1β production in keratinocytes by activating p38 MAPK signaling in psoriasis.Cyr61 is involved in neutrophil infiltration in joints by inducing IL-8 production by fibroblast-like synoviocytes in rheumatoid arthritis.The role of cytokines in skin aging.Danger signals in the initiation of the inflammatory response after myocardial infarction.Systemic overexpression of matricellular protein CCN1 exacerbates obliterative bronchiolitis in mouse tracheal allografts.The role of CCN family genes in haematological malignancies.

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P2860

Matricellular protein CCN1 activates a proinflammatory genetic program in murine macrophages

http://www.wikidata.org/entity/Q24633369

description

2010 nî lūn-bûn

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2010 թուականի Մարտին հրատարակուած գիտական յօդուած

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2010 թվականի մարտին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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name

Matricellular protein CCN1 act ...... program in murine macrophages

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Matricellular protein CCN1 act ...... program in murine macrophages

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Matricellular protein CCN1 act ...... program in murine macrophages

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type

label

Matricellular protein CCN1 act ...... program in murine macrophages

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Matricellular protein CCN1 act ...... program in murine macrophages

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Matricellular protein CCN1 act ...... program in murine macrophages

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prefLabel

Matricellular protein CCN1 act ...... program in murine macrophages

@ast

Matricellular protein CCN1 act ...... program in murine macrophages

@en

Matricellular protein CCN1 act ...... program in murine macrophages

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JIMMUNOL.0902792

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Journal of Immunology

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Matricellular protein CCN1 act ...... program in murine macrophages

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Chih-Chiun Chen

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Tao Bai

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P2860

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

Fas-mediated apoptosis is regulated by the extracellular matrix protein CCN1 (CYR61) in vitro and in vivo

CYR61 (CCN1) is essential for placental development and vascular integrity

The p38/RK mitogen-activated protein kinase pathway regulates interleukin-6 synthesis response to tumor necrosis factor

Functions and mechanisms of action of CCN matricellular proteins

CYR61, a product of a growth factor-inducible immediate early gene, promotes angiogenesis and tumor growth

Matrix protein CCN1 is critical for prostate carcinoma cell proliferation and TRAIL-induced apoptosis

Exploring the full spectrum of macrophage activation

Fragments of extracellular matrix as mediators of inflammation

The matricellular protein CCN1 is essential for cardiac development

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20164416

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