Smad3 deficiency in mice protects against insulin resistance and obesity induced by a high-fat diet - Test2 - elhamkhani - TriplyDB

Smad3 deficiency in mice protects against insulin resistance and obesity induced by a high-fat diet

Smad3 deficiency in mice protects against insulin resistance and obesity induced by a high-fat diet

http://www.wikidata.org/entity/Q24633409

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SMAD3 deficiency promotes inflammatory aortic aneurysms in angiotensin II-infused mice via activation of iNOS Getting 'Smad' about obesity and diabetes Systems biology approach reveals genome to phenome correlation in type 2 diabetes miR-217 regulates ethanol-induced hepatic inflammation by disrupting sirtuin 1-lipin-1 signaling.Pid1 induces insulin resistance in both human and mouse skeletal muscle during obesity Redox control of p53 in the transcriptional regulation of TGF-β1 target genes through SMAD cooperativity.Upregulation of Tumor Necrosis Factor-α-Induced Protein 8-Like 2 mRNA Is Negatively Correlated with Serum Concentrations of Tumor Necrosis Factor-α and Interleukin 6 in Type 2 Diabetes Mellitus Progression of diet induced nonalcoholic steatohepatitis is accompanied by increased expression of Kruppel-like-factor 10 in mice.Mechanisms of insulin resistance in obesity SMAD3 negatively regulates serum irisin and skeletal muscle FNDC5 and peroxisome proliferator-activated receptor γ coactivator 1-α (PGC-1α) during exercise.Voluntary physical activity prevents insulin resistance in a tissue specific manner Obesity Resistance and Enhanced Insulin Sensitivity in Ahnak-/- Mice Fed a High Fat Diet Are Related to Impaired Adipogenesis and Increased Energy Expenditure.MAGP1, the extracellular matrix, and metabolism.Copy number variation in exportin-4 (XPO4) gene and its association with histological severity of non-alcoholic fatty liver disease.Blockade of the activin receptor IIb activates functional brown adipogenesis and thermogenesis by inducing mitochondrial oxidative metabolism Interaction of Wnt pathway related variants with type 2 diabetes in a Chinese Han population.Hyperhomocysteinemia promotes insulin resistance by inducing endoplasmic reticulum stress in adipose tissue Prednisolone induces the Wnt signalling pathway in 3T3-L1 adipocytes.C-Reactive Protein Promotes Diabetic Kidney Disease in db/db Mice via the CD32b-Smad3-mTOR signaling Pathway.High fat diet-induced TGF-β/Gbb signaling provokes insulin resistance through the tribbles expression.Activin-like kinase 2 functions in peri-implantation uterine signaling in mice and humans Transforming growth factor beta signaling in hepatocytes participates in steatohepatitis through regulation of cell death and lipid metabolism in mice Systemic Regulators of Skeletal Muscle Regeneration in Obesity.Antipsychotics activate the TGFβ pathway effector SMAD3 System Level Meta-analysis of Microarray Datasets for Elucidation of Diabetes Mellitus Pathobiology.The kielin/chordin-like protein KCP attenuates nonalcoholic fatty liver disease in mice.Type 2 immunity is protective in metabolic disease but exacerbates NAFLD collaboratively with TGF-β.MiR-1 suppresses tumor cell proliferation in colorectal cancer by inhibition of Smad3-mediated tumor glycolysis.Rosmarinic acid suppresses adipogenesis, lipolysis in 3T3-L1 adipocytes, lipopolysaccharide-stimulated tumor necrosis factor-α secretion in macrophages, and inflammatory mediators in 3T3-L1 adipocytes.Characterization of metabolic health in mouse models of fibrillin-1 perturbation.Transforming growth factor-β signaling pathway-associated genes SMAD2 and TGFBR2 are implicated in metabolic syndrome in a Taiwanese population.Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.Metformin ameliorates skeletal muscle insulin resistance by inhibiting miR-21 expression in a high-fat dietary rat model.MicroRNA and Adipogenesis.Smad proteins differentially regulate obesity-induced glucose and lipid abnormalities and inflammation via class-specific control of AMPK-related kinase MPK38/MELK activity.

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P2860

Smad3 deficiency in mice protects against insulin resistance and obesity induced by a high-fat diet

http://www.wikidata.org/entity/Q24633409

description

2011 nî lūn-bûn

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2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի փետրվարին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Smad3 deficiency in mice prote ...... ity induced by a high-fat diet

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Smad3 deficiency in mice prote ...... ity induced by a high-fat diet

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Smad3 deficiency in mice prote ...... ity induced by a high-fat diet

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Smad3 deficiency in mice prote ...... ity induced by a high-fat diet

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Smad3 deficiency in mice prote ...... ity induced by a high-fat diet

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Smad3 deficiency in mice prote ...... ity induced by a high-fat diet

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Smad3 deficiency in mice prote ...... ity induced by a high-fat diet

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Smad3 deficiency in mice prote ...... ity induced by a high-fat diet

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Smad3 deficiency in mice prote ...... ity induced by a high-fat diet

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Chek Kun Tan

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Ming Jie Tan

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Nguan Soon Tan

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Nicolas Leuenberger

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Ravi Kambadur

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Walter Wahli

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Yew Wai Yan

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Yinghui Chen

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P2860

PPAR delta: a dagger in the heart of the metabolic syndrome.

Essential role of Smad3 in the inhibition of inflammation-induced PPARbeta/delta expression

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

Regulation of epithelial-mesenchymal IL-1 signaling by PPARbeta/delta is essential for skin homeostasis and wound healing

TGFbeta signaling in growth control, cancer, and heritable disorders

Cytokines suppress adipogenesis and PPAR-gamma function through the TAK1/TAB1/NIK cascade

CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription

Glucose and fat metabolism in adipose tissue of acetyl-CoA carboxylase 2 knockout mice

Muscle-specific Pparg deletion causes insulin resistance

Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta

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464-76

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scholarly article

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1282620

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10.2337/DB10-0801

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2

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60

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49788271

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21270259

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3028346

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