Molecular insights into the function of RING finger (RNF)-containing proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent ubiquitylation
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Ubc13: the Lys63 ubiquitin chain building machineStructural basis for role of ring finger protein RNF168 RING domainHistone modifications and DNA double-strand break repair after exposure to ionizing radiations.RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor RecruitmentEGLN2 and RNF150 genetic variants are associated with chronic obstructive pulmonary disease risk in the Chinese population.Identification and comparative analysis of the Tegillarca granosa haemocytes microRNA transcriptome in response to Cd using a deep sequencing approach.HTLV-1 Tax Stimulates Ubiquitin E3 Ligase, Ring Finger Protein 8, to Assemble Lysine 63-Linked Polyubiquitin Chains for TAK1 and IKK Activation.Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting.RING Dimerization Links Higher-Order Assembly of TRIM5α to Synthesis of K63-Linked Polyubiquitin.New Insights into the RNA-Binding and E3 Ubiquitin Ligase Activities of Roquins.Chromatin modifications and the DNA damage response to ionizing radiation.Identification of RNF8 as a ubiquitin ligase involved in targeting the p12 subunit of DNA polymerase δ for degradation in response to DNA damageRNF168 forms a functional complex with RAD6 during the DNA damage responseIt takes two to tango: Ubiquitin and SUMO in the DNA damage response.BRCA1 in the DNA damage response and at telomeresRNF168 cooperates with RNF8 to mediate FOXM1 ubiquitination and degradation in breast cancer epirubicin treatmentStructural mechanisms underlying signaling in the cellular response to DNA double strand breaks.Touch, act and go: landing and operating on nucleosomes.Histone modifications in DNA damage response.Specificity and disease in the ubiquitin systemHistone Modifications and Cancer.The N-terminal ubiquitin-associated domain of Cezanne is crucial for its function to suppress NF-κB pathway.Allosteric activation of the RNF146 ubiquitin ligase by a poly(ADP-ribosyl)ation signal.The nucleosome acidic patch plays a critical role in RNF168-dependent ubiquitination of histone H2A.BRCA1 is a histone-H2A-specific ubiquitin ligase.Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaksUbiquitination of the PI3-kinase VPS-34 promotes VPS-34 stability and phagosome maturation.Structural insights into two distinct binding modules for Lys63-linked polyubiquitin chains in RNF168.An E2-guided E3 Screen Identifies the RNF17-UBE2U Pair as Regulator of the Radiosensitivity, Immunodeficiency, Dysmorphic Features, and Learning Difficulties (RIDDLE) Syndrome Protein RNF168.RNF8 binds phosphorylated MDC1 at DNA DSBsHERC2 facilitates UBE2N:UBE2V2 binding to RNF8RNF168 binds DNA DSBsRNF8 and RNF168 ubiquitinate H2AFXUbe2V2 Is a Rosetta Stone Bridging Redox and Ubiquitin Codes, Coordinating DNA Damage Responses.
P2860
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P2860
Molecular insights into the function of RING finger (RNF)-containing proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent ubiquitylation
description
2012 nî lūn-bûn
@nan
2012 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Molecular insights into the fu ...... /Mms2-dependent ubiquitylation
@ast
Molecular insights into the fu ...... /Mms2-dependent ubiquitylation
@en
Molecular insights into the fu ...... /Mms2-dependent ubiquitylation
@nl
type
label
Molecular insights into the fu ...... /Mms2-dependent ubiquitylation
@ast
Molecular insights into the fu ...... /Mms2-dependent ubiquitylation
@en
Molecular insights into the fu ...... /Mms2-dependent ubiquitylation
@nl
altLabel
Molecular Insights into the Fu ...... /Mms2-dependent Ubiquitylation
@en
prefLabel
Molecular insights into the fu ...... /Mms2-dependent ubiquitylation
@ast
Molecular insights into the fu ...... /Mms2-dependent ubiquitylation
@en
Molecular insights into the fu ...... /Mms2-dependent ubiquitylation
@nl
P2093
P2860
P3181
P356
P1476
Molecular insights into the fu ...... /Mms2-dependent ubiquitylation
@en
P2093
Charles C Y Leung
J N Mark Glover
Ross A Edwards
Sirano Dhe-Paganon
Stephen J Campbell
P2860
P304
23900-23910
P3181
P356
10.1074/JBC.M112.359653
P407
P577
2012-05-15T00:00:00Z