Posttranslational regulation of keratins: degradation of mouse and human keratins 18 and 8
about
Mouse differentiation-specific keratins 1 and 10 require a preexisting keratin scaffold to form a filament networkMutation of human keratin 18 in association with cryptogenic cirrhosisIsolation, sequence, and expression of a human keratin K5 gene: transcriptional regulation of keratins and insights into pairwise controlOverexpression of the human NFM subunit in transgenic mice modifies the level of endogenous NFL and the phosphorylation state of NFH subunitsIncreased expression of keratin 16 causes anomalies in cytoarchitecture and keratinization in transgenic mouse skinCaspase cleavage of keratin 18 and reorganization of intermediate filaments during epithelial cell apoptosisThe recognition component of the N-end rule pathwayKeratin-dependent, epithelial resistance to tumor necrosis factor-induced apoptosisCytokeratins 8 and 19 in the mouse placental developmentIntermediate filaments: a historical perspectiveDirected expression of a chimeric type II keratin partially rescues keratin 5-null mice.Oncogenic regulation and function of keratins 8 and 18.Two mechanisms regulate keratin K15 expression in keratinocytes: role of PKC/AP-1 and FOXM1 mediated signalling.Targeted deletion of keratins 18 and 19 leads to trophoblast fragility and early embryonic lethalityDiscovering functional relationships between RNA expression and chemotherapeutic susceptibility using relevance networks.Expression of cytokeratin confers multiple drug resistanceDifferential expression of cytokeratin mRNA and protein in normal prostate, prostatic intraepithelial neoplasia, and invasive carcinoma.Identification of genes expressed in premalignant breast disease by microscopy-directed cloning.Epithelial-specific keratin gene expression: identification of a 300 base-pair controlling segment.Markers for dysplasia of the upper aerodigestive tract. Suprabasal expression of PCNA, p53, and CK19 in alcohol-fixed, embedded tissue.A single human keratin 18 gene is expressed in diverse epithelial cells of transgenic miceEctopic synthesis of epidermal cytokeratins in pancreatic islet cells of transgenic mice interferes with cytoskeletal order and insulin production.Dynamics of keratin assembly: exogenous type I keratin rapidly associates with type II keratin in vivo.Chronic hepatitis, hepatocyte fragility, and increased soluble phosphoglycokeratins in transgenic mice expressing a keratin 18 conserved arginine mutant.Regulation of keratin and integrin gene expression in cancer and drug resistance.Hepatocyte nuclear factor 4 provokes expression of epithelial marker genes, acting as a morphogen in dedifferentiated hepatoma cells.Expression of complete keratin filaments in mouse L cells augments cell migration and invasionKeratin 8 overexpression promotes mouse Mallory body formation.A small surface hydrophobic stripe in the coiled-coil domain of type I keratins mediates tetramer stability.Keratin overexpression levels correlate with the extent of spontaneous pancreatic injury.Polarized and functional epithelia can form after the targeted inactivation of both mouse keratin 8 alleles.The desmoplakin carboxyl terminus coaligns with and specifically disrupts intermediate filament networks when expressed in cultured cells.AP-1, ETS, and transcriptional silencers regulate retinoic acid-dependent induction of keratin 18 in embryonic cells.Transcriptional insulation of the human keratin 18 gene in transgenic miceAlu sequence involvement in transcriptional insulation of the keratin 18 gene in transgenic miceKeratin mutation predisposes to mouse liver fibrosis and unmasks differential effects of the carbon tetrachloride and thioacetamide models.Structure and functions of keratin proteins in simple, stratified, keratinized and cornified epithelia.Sindbis virus RNA polymerase is degraded by the N-end rule pathway.Formation of a normal epidermis supported by increased stability of keratins 5 and 14 in keratin 10 null mice.Complete cytolysis and neonatal lethality in keratin 5 knockout mice reveal its fundamental role in skin integrity and in epidermolysis bullosa simplex.
P2860
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P2860
Posttranslational regulation of keratins: degradation of mouse and human keratins 18 and 8
description
1989 nî lūn-bûn
@nan
1989 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
Posttranslational regulation o ...... se and human keratins 18 and 8
@ast
Posttranslational regulation o ...... se and human keratins 18 and 8
@en
Posttranslational regulation o ...... se and human keratins 18 and 8
@nl
type
label
Posttranslational regulation o ...... se and human keratins 18 and 8
@ast
Posttranslational regulation o ...... se and human keratins 18 and 8
@en
Posttranslational regulation o ...... se and human keratins 18 and 8
@nl
prefLabel
Posttranslational regulation o ...... se and human keratins 18 and 8
@ast
Posttranslational regulation o ...... se and human keratins 18 and 8
@en
Posttranslational regulation o ...... se and human keratins 18 and 8
@nl
P2093
P2860
P356
P1476
Posttranslational regulation o ...... se and human keratins 18 and 8
@en
P2093
P2860
P304
P356
10.1128/MCB.9.4.1553
P407
P577
1989-04-01T00:00:00Z