Inactive-state preassembly of G(q)-coupled receptors and G(q) heterotrimers
about
Rab26 modulates the cell surface transport of α2-adrenergic receptors from the GolgiCommunication over the network of binary switches regulates the activation of A2A adenosine receptorTransmembrane signal transduction by peptide hormones via family B G protein-coupled receptorsSingle-molecule analysis of fluorescently labeled G-protein-coupled receptors reveals complexes with distinct dynamics and organizationM3 muscarinic receptor interaction with phospholipase C β3 determines its signaling efficiency.Desensitization of functional µ-opioid receptors increases agonist off-rate.Diverse cell type-specific mechanisms localize G protein-coupled receptors to Caenorhabditis elegans sensory ciliaSubtype differences in pre-coupling of muscarinic acetylcholine receptors.A single lys residue on the first intracellular loop modulates the endoplasmic reticulum export and cell-surface expression of α2A-adrenergic receptorHelix 8 and the i3 loop of the muscarinic M3 receptor are crucial sites for its regulation by the Gβ5-RGS7 complex.Ghrelin receptor conformational dynamics regulate the transition from a preassembled to an active receptor:Gq complexCCR5 conformations are dynamic and modulated by localization, trafficking and G protein associationCyclic Adenosine 3',5'-Monophosphate Elevation and Biological Signaling through a Secretin Family Gs-Coupled G Protein-Coupled Receptor Are Restricted to a Single Adenylate Cyclase Isoform.From atomic structures to neuronal functions of g protein-coupled receptorsG-protein-coupled receptor interaction with small GTPases.Leukocyte arrest: Biomechanics and molecular mechanisms of β2 integrin activationWNT Stimulation Dissociates a Frizzled 4 Inactive-State Complex with Gα12/13.Label-free cell phenotypic assessment of the biased agonism and efficacy of agonists at the endogenous muscarinic M3 receptors.Interaction of Protease-Activated Receptor 2 with G Proteins and β-Arrestin 1 Studied by Bioluminescence Resonance Energy Transfer.Structural Aspects of GPCR-G Protein Coupling.Sensitive and high resolution localization and tracking of membrane proteins in live cells with BRET.Regulation of β2-adrenergic receptor function by conformationally selective single-domain intrabodies.Role of cyclic AMP in the eye with glaucoma.Agonist high- and low-affinity states of dopamine D₂ receptors: methods of detection and clinical implications.Biased agonism at G protein-coupled receptors: the promise and the challenges--a medicinal chemistry perspective.Single-molecule analysis of ligand efficacy in β2AR-G-protein activation.Mapping structural determinants within third intracellular loop that direct signaling specificity of type 1 corticotropin-releasing hormone receptorCa2+ signaling in cytoskeletal reorganization, cell migration, and cancer metastasis.Investigation of Inhibition Mechanism of Chemokine Receptor CCR5 by Micro-second Molecular Dynamics Simulations.ER/K linked GPCR-G protein fusions systematically modulate second messenger response in cellsG protein stoichiometry dictates biased agonism through distinct receptor-G protein partitioning.Receptor-G protein interaction studied by bioluminescence resonance energy transfer: lessons from protease-activated receptor 1.Priming GPCR signaling through the synergistic effect of two G proteins.The G protein Gi1 exhibits basal coupling but not preassembly with G protein-coupled receptors.Single-molecule imaging reveals receptor-G protein interactions at cell surface hot spots.G protein coupled receptor signaling complexes in live cells.Development of novel biosensors to study receptor-mediated activation of the G-protein α subunits Gs and Golf.A Protein Preparation Method for the High-throughput Identification of Proteins Interacting with a Nuclear Cofactor Using LC-MS/MS Analysis.
P2860
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P2860
Inactive-state preassembly of G(q)-coupled receptors and G(q) heterotrimers
description
2011 nî lūn-bûn
@nan
2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Inactive-state preassembly of G(q)-coupled receptors and G(q) heterotrimers
@ast
Inactive-state preassembly of G(q)-coupled receptors and G(q) heterotrimers
@en
Inactive-state preassembly of G(q)-coupled receptors and G(q) heterotrimers
@nl
type
label
Inactive-state preassembly of G(q)-coupled receptors and G(q) heterotrimers
@ast
Inactive-state preassembly of G(q)-coupled receptors and G(q) heterotrimers
@en
Inactive-state preassembly of G(q)-coupled receptors and G(q) heterotrimers
@nl
prefLabel
Inactive-state preassembly of G(q)-coupled receptors and G(q) heterotrimers
@ast
Inactive-state preassembly of G(q)-coupled receptors and G(q) heterotrimers
@en
Inactive-state preassembly of G(q)-coupled receptors and G(q) heterotrimers
@nl
P2093
P2860
P356
P1476
Inactive-state preassembly of G(q)-coupled receptors and G(q) heterotrimers
@en
P2093
Chunmin Dong
Guangyu Wu
Nevin A Lambert
P2860
P2888
P356
10.1038/NCHEMBIO.642
P407
P577
2011-10-01T00:00:00Z
P5875
P6179
1013559612