Plasmodium falciparum genome-wide scans for positive selection, recombination hot spots and resistance to antimalarial drugs - Test2 - elhamkhani - TriplyDB

Plasmodium falciparum genome-wide scans for positive selection, recombination hot spots and resistance to antimalarial drugs

Plasmodium falciparum genome-wide scans for positive selection, recombination hot spots and resistance to antimalarial drugs

http://www.wikidata.org/entity/Q24642214

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Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing Artemisinin-resistant malaria: research challenges, opportunities, and public health implications Genome scanning of Amazonian Plasmodium falciparum shows subtelomeric instability and clindamycin-resistant parasites Drug resistance genomics of the antimalarial drug artemisinin Targeting Plasmodium falciparum Hsp90: Towards Reversing Antimalarial Resistance Antimalarial efficacy of piperaquine-based antimalarial combination therapies: facts and uncertainties Application of genomics to field investigations of malaria by the international centers of excellence for malaria research A HECT ubiquitin-protein ligase as a novel candidate gene for altered quinine and quinidine responses in Plasmodium falciparum PfCRT and its role in antimalarial drug resistance Genome-wide association analysis identifies genetic loci associated with resistance to multiple antimalarials in Plasmodium falciparum from China-Myanmar border An optimized microarray platform for assaying genomic variation in Plasmodium falciparum field populations Antimalarial drug resistance in Africa: key lessons for the future Advances in genetics and genomics: use and limitations in achieving malaria elimination goals Identification of a mutant PfCRT-mediated chloroquine tolerance phenotype in Plasmodium falciparum Identification and functional validation of the novel antimalarial resistance locus PF10_0355 in Plasmodium falciparum Population genetic analysis of Plasmodium falciparum parasites using a customized Illumina GoldenGate genotyping assay The activities of current antimalarial drugs on the life cycle stages of Plasmodium: a comparative study with human and rodent parasites In vitro sensitivity of Plasmodium falciparum from China-Myanmar border area to major ACT drugs and polymorphisms in potential target genes Improving pharmacokinetic-pharmacodynamic modeling to investigate anti-infective chemotherapy with application to the current generation of antimalarial drugs Imputation-based population genetics analysis of Plasmodium falciparum malaria parasites Whole Genome Sequencing of Field Isolates Reveals Extensive Genetic Diversity in Plasmodium vivax from Colombia Molecular Mechanisms for Drug Hypersensitivity Induced by the Malaria Parasite's Chloroquine Resistance Transporter PfCRT and PfMDR1 modulate interactions of artemisinin derivatives and ion channel blockers Mutations in the Plasmodium falciparum Cyclic Amine Resistance Locus (PfCARL) Confer Multidrug Resistance A Population Genomics Approach to Assessing the Genetic Basis of Within-Host Microevolution Underlying Recurrent Cryptococcal Meningitis Infection.Genome-wide screen identifies new candidate genes associated with artemisinin susceptibility in Plasmodium falciparum in Kenya Population genomic scan for candidate signatures of balancing selection to guide antigen characterization in malaria parasites.Genome-wide association studies in Plasmodium species Analysis of malaria parasite phenotypes using experimental genetic crosses of Plasmodium falciparum.An adaptable two-color flow cytometric assay to quantitate the invasion of erythrocytes by Plasmodium falciparum parasites.Genome-wide polymorphisms and development of a microarray platform to detect genetic variations in Plasmodium yoelii.Genetic mapping identifies novel highly protective antigens for an apicomplexan parasite Discovery of new antimalarial chemotypes through chemical methodology and library development Applied genomics: data mining reveals species-specific malaria diagnostic targets more sensitive than 18S rRNA.Plasmodium falciparum multidrug resistance protein 1 (pfmrp1) gene and its association with in vitro drug susceptibility of parasite isolates from north-east Myanmar Artemisinin resistance in Plasmodium falciparum is associated with an altered temporal pattern of transcription.Protein-based signatures of functional evolution in Plasmodium falciparum.Evolution of eukaryotic microbial pathogens via covert sexual reproduction Recurrent bottlenecks in the malaria life cycle obscure signals of positive selection.Recent Progress in Functional Genomic Research in Plasmodium falciparum

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Plasmodium falciparum genome-wide scans for positive selection, recombination hot spots and resistance to antimalarial drugs

http://www.wikidata.org/entity/Q24642214

description

2010 nî lūn-bûn

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2010 թուականի Մարտին հրատարակուած գիտական յօդուած

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2010 թվականի մարտին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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Plasmodium falciparum genome-w ...... sistance to antimalarial drugs

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Plasmodium falciparum genome-w ...... sistance to antimalarial drugs

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Plasmodium falciparum genome-w ...... sistance to antimalarial drugs

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Nature Genetics

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Plasmodium falciparum genome-w ...... sistance to antimalarial drugs

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Daniel E Sturdevant

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Duong Socheat

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Fengzhen Ou

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Guoqiao Li

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Haibo Li

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Hongying Jiang

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Jianbing Mu

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Jianping Song

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May Ho

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Michael Waisberg

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Declining artesunate-mefloquine efficacy against falciparum malaria on the Cambodia-Thailand border

A map of recent positive selection in the human genome

Evidence of Artemisinin-Resistant Malaria in Western Cambodia

Detecting recent positive selection in the human genome from haplotype structure

Genome-wide detection and characterization of positive selection in human populations

Inference of population structure using multilocus genotype data

Signals of recent positive selection in a worldwide sample of human populations

Use of high-density tiling microarrays to identify mutations globally and elucidate mechanisms of drug resistance in Plasmodium falciparum

PLINK: a tool set for whole-genome association and population-based linkage analyses

Recombination hotspots and population structure in Plasmodium falciparum

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268-71

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scholarly article

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1842413

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10.1038/NG.528

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3

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42

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Nicholas John White

Kesinee Chotivanich

Rick M. Fairhurst

Srivicha Krudsood

Polrat Wilairatana

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2010-03-01T00:00:00Z

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41139545

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1052899355

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20101240

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Plasmodium falciparum

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2828519

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