uPAR promotes formation of the p130Cas-Crk complex to activate Rac through DOCK180.
about
MicroRNA-200 family members differentially regulate morphological plasticity and mode of melanoma cell invasionPseudopodium-enriched atypical kinase 1 regulates the cytoskeleton and cancer progression [corrected].CAS proteins in normal and pathological cell growth controlPhysical view on migration modesStructural Basis of Membrane Targeting by the Dock180 Family of Rho Family Guanine Exchange Factors (Rho-GEFs)Protein-tyrosine kinase 6 promotes peripheral adhesion complex formation and cell migration by phosphorylating p130 CRK-associated substrateModels of crk adaptor proteins in cancer.Regulation of focal adhesion and cell migration by ANKRD28-DOCK180 interactionNeutralizing the EGF receptor in glioblastoma cells stimulates cell migration by activating uPAR-initiated cell signaling.Paxillin-kinase-linker tyrosine phosphorylation regulates directional cell migration.ELMO recruits actin cross-linking family 7 (ACF7) at the cell membrane for microtubule capture and stabilization of cellular protrusionsRSK is a principal effector of the RAS-ERK pathway for eliciting a coordinate promotile/invasive gene program and phenotype in epithelial cells.Heme oxygenase-1 in the forefront of a multi-molecular network that governs cell-cell contacts and filopodia-induced zippering in prostate cancer.The Rac-specific exchange factors Dock1 and Dock5 are dispensable for the establishment of the glomerular filtration barrier in vivo.MMP-9, uPAR and cathepsin B silencing downregulate integrins in human glioma xenograft cells in vitro and in vivo in nude mice.Suppression of uPAR retards radiation-induced invasion and migration mediated by integrin β1/FAK signaling in medulloblastoma.Soluble Urokinase Receptor and the Kidney Response in Diabetes Mellitus.Stochastic Dynamics of Membrane Protrusion Mediated by the DOCK180/Rac Pathway in Migrating CellsUrokinase-type plasminogen activator receptor signaling is critical in nasopharyngeal carcinoma cell growth and metastasis.CCN2 is required for the TGF-β induced activation of Smad1-Erk1/2 signaling networkStochastic models of cell protrusion arising from spatiotemporal signaling and adhesion dynamicsHigh molecular weight kininogen binds phosphatidylserine and opsonizes urokinase plasminogen activator receptor-mediated efferocytosis.Down-regulation of 5-HT1B and 5-HT1D receptors inhibits proliferation, clonogenicity and invasion of human pancreatic cancer cellsEmerging role of paxillin-PKL in regulation of cell adhesion, polarity and migrationElongation factor-2 kinase regulates TG2/β1 integrin/Src/uPAR pathway and epithelial-mesenchymal transition mediating pancreatic cancer cells invasionAxl phosphorylates Elmo scaffold proteins to promote Rac activation and cell invasion.A urokinase receptor-Bim signaling axis emerges during EGFR inhibitor resistance in mutant EGFR glioblastoma.Crosstalk between the urokinase-type plasminogen activator receptor and EGF receptor variant III supports survival and growth of glioblastoma cells.A new class of orthosteric uPAR·uPA small-molecule antagonists are allosteric inhibitors of the uPAR·vitronectin interactionA novel function for Cyclin A2: control of cell invasion via RhoA signaling.Genome-Wide Association Study between Single Nucleotide Polymorphisms and Flight Speed in Nellore CattleA transformation in the mechanism by which the urokinase receptor signals provides a selection advantage for estrogen receptor-expressing breast cancer cells in the absence of estrogenThe Rac1 exchange factor Dock5 is essential for bone resorption by osteoclasts.Role of integrins in regulating proteases to mediate extracellular matrix remodelingRac-specific guanine nucleotide exchange factor DOCK1 is a critical regulator of HER2-mediated breast cancer metastasis.SNX9 promotes metastasis by enhancing cancer cell invasion via differential regulation of RhoGTPases.Role of urokinase receptor in tumor progression and development.Mannose 6-phosphate/insulin-like growth factor 2 receptor limits cell invasion by controlling alphaVbeta3 integrin expression and proteolytic processing of urokinase-type plasminogen activator receptor.Tumor-associated soluble uPAR-directed endothelial cell motility and tumor angiogenesis.The urokinase plasminogen activator receptor promotes efferocytosis of apoptotic cells.
P2860
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P2860
uPAR promotes formation of the p130Cas-Crk complex to activate Rac through DOCK180.
description
2008 nî lūn-bûn
@nan
2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
uPAR promotes formation of the p130Cas-Crk complex to activate Rac through DOCK180
@nl
uPAR promotes formation of the p130Cas-Crk complex to activate Rac through DOCK180.
@ast
uPAR promotes formation of the p130Cas-Crk complex to activate Rac through DOCK180.
@en
type
label
uPAR promotes formation of the p130Cas-Crk complex to activate Rac through DOCK180
@nl
uPAR promotes formation of the p130Cas-Crk complex to activate Rac through DOCK180.
@ast
uPAR promotes formation of the p130Cas-Crk complex to activate Rac through DOCK180.
@en
prefLabel
uPAR promotes formation of the p130Cas-Crk complex to activate Rac through DOCK180
@nl
uPAR promotes formation of the p130Cas-Crk complex to activate Rac through DOCK180.
@ast
uPAR promotes formation of the p130Cas-Crk complex to activate Rac through DOCK180.
@en
P2860
P3181
P356
P1476
uPAR promotes formation of the p130Cas-Crk complex to activate Rac through DOCK180.
@en
P2093
Christopher J Marshall
Harvey W Smith
P2860
P304
P3181
P356
10.1083/JCB.200712050
P407
P577
2008-08-01T00:00:00Z