In vivo activation of midbrain dopamine neurons via sensitized, high-affinity alpha 6 nicotinic acetylcholine receptors
about
Cognitive enhancers for the treatment of ADHDCrucial roles of the CHRNB3-CHRNA6 gene cluster on chromosome 8 in nicotine dependence: update and subjects for future researchOrthosteric and Allosteric Ligands of Nicotinic Acetylcholine Receptors for Smoking CessationMolecular mechanisms underlying behaviors related to nicotine addictionMolecules and circuits involved in nicotine addiction: The many faces of smokingPreclinical evidence that activation of mesolimbic alpha 6 subunit containing nicotinic acetylcholine receptors supports nicotine addiction phenotypeMechanistic insights into nicotine withdrawal.Stable expression and functional characterization of a human nicotinic acetylcholine receptor with α6β2 properties: discovery of selective antagonistsBehavioral and molecular analysis of nicotine-conditioned place preference in zebrafishRoles for N-terminal extracellular domains of nicotinic acetylcholine receptor (nAChR) β3 subunits in enhanced functional expression of mouse α6β2β3- and α6β4β3-nAChRs.Replicated Risk Nicotinic Cholinergic Receptor Genes for Nicotine Dependence.Significant associations of CHRNA2 and CHRNA6 with nicotine dependence in European American and African American populationsAnalysis of rare variations reveals roles of amino acid residues in the N-terminal extracellular domain of nicotinic acetylcholine receptor (nAChR) alpha6 subunit in the functional expression of human alpha6*-nAChRs.Insights into the neurobiology of the nicotinic cholinergic system and nicotine addiction from mice expressing nicotinic receptors harboring gain-of-function mutationsElimination of the vesicular acetylcholine transporter in the striatum reveals regulation of behaviour by cholinergic-glutamatergic co-transmission.Nicotinic receptor-mediated reduction in L-DOPA-induced dyskinesias may occur via desensitizationAlpha-conotoxin MII-sensitive nicotinic acetylcholine receptors in the nucleus accumbens shell regulate progressive ratio responding maintained by nicotine.Altered activity-rest patterns in mice with a human autosomal-dominant nocturnal frontal lobe epilepsy mutation in the β2 nicotinic receptor.Cholinergic Mesopontine Signals Govern Locomotion and Reward through Dissociable Midbrain Pathways.Structural differences determine the relative selectivity of nicotinic compounds for native alpha 4 beta 2*-, alpha 6 beta 2*-, alpha 3 beta 4*- and alpha 7-nicotine acetylcholine receptorsIndolizidine (-)-235B' and related structural analogs: discovery of nicotinic receptor antagonists that inhibit nicotine-evoked [3H]dopamine releasePre-clinical properties of the alpha4beta2 nicotinic acetylcholine receptor partial agonists varenicline, cytisine and dianicline translate to clinical efficacy for nicotine dependence.Differential expression and function of nicotinic acetylcholine receptors in subdivisions of medial habenulaMolecular genetics and imaging technologies for circuit-based neuroanatomy.Progress and challenges in the study of α6-containing nicotinic acetylcholine receptors.Chrna4 A529 knock-in mice exhibit altered nicotine sensitivity.Presynaptic GABAB autoreceptor regulation of nicotinic acetylcholine receptor mediated [(3)H]-GABA release from mouse synaptosomes.Subtype-specific mechanisms for functional interaction between α6β4* nicotinic acetylcholine receptors and P2X receptorsAcute ethanol inhibits dopamine release in the nucleus accumbens via α6 nicotinic acetylcholine receptorsAcetylcholine as a neuromodulator: cholinergic signaling shapes nervous system function and behavior.Nicotinic receptor antagonists as treatments for nicotine abuse.Expression of functional human α6β2β3* acetylcholine receptors in Xenopus laevis oocytes achieved through subunit chimeras and concatamers.Menthol Alone Upregulates Midbrain nAChRs, Alters nAChR Subtype Stoichiometry, Alters Dopamine Neuron Firing Frequency, and Prevents Nicotine Reward.α2* Nicotinic acetylcholine receptors influence hippocampus-dependent learning and memory in adolescent mice.Functional nicotinic acetylcholine receptors containing α6 subunits are on GABAergic neuronal boutons adherent to ventral tegmental area dopamine neurons.bPiDI: a novel selective α6β2* nicotinic receptor antagonist and preclinical candidate treatment for nicotine abuse.Transcriptional regulation by nicotine in dopaminergic neurons.Distinct contributions of nicotinic acetylcholine receptor subunit alpha4 and subunit alpha6 to the reinforcing effects of nicotine.The necessity of α4* nicotinic receptors in nicotine-driven behaviors: dissociation between reinforcing and motor effects of nicotine.Effects of tobacco smoke constituents, anabasine and anatabine, on memory and attention in female rats.
P2860
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P2860
In vivo activation of midbrain dopamine neurons via sensitized, high-affinity alpha 6 nicotinic acetylcholine receptors
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
In vivo activation of midbrain ...... otinic acetylcholine receptors
@ast
In vivo activation of midbrain ...... otinic acetylcholine receptors
@en
In vivo activation of midbrain ...... otinic acetylcholine receptors
@nl
type
label
In vivo activation of midbrain ...... otinic acetylcholine receptors
@ast
In vivo activation of midbrain ...... otinic acetylcholine receptors
@en
In vivo activation of midbrain ...... otinic acetylcholine receptors
@nl
prefLabel
In vivo activation of midbrain ...... otinic acetylcholine receptors
@ast
In vivo activation of midbrain ...... otinic acetylcholine receptors
@en
In vivo activation of midbrain ...... otinic acetylcholine receptors
@nl
P2093
P2860
P921
P3181
P1433
P1476
In vivo activation of midbrain ...... otinic acetylcholine receptors
@en
P2093
Henry A Lester
J Michael McIntosh
Julie M Miwa
Merouane Bencherif
Michael J Marks
Nathaniel Heintz
Paul Whiteaker
Ryan M Drenan
Sharon R Grady
Sheri McKinney
P2860
P304
P3181
P356
10.1016/J.NEURON.2008.09.009
P407
P577
2008-10-09T00:00:00Z