In vivo activation of midbrain dopamine neurons via sensitized, high-affinity alpha 6 nicotinic acetylcholine receptors - Test2 - elhamkhani - TriplyDB

In vivo activation of midbrain dopamine neurons via sensitized, high-affinity alpha 6 nicotinic acetylcholine receptors

In vivo activation of midbrain dopamine neurons via sensitized, high-affinity alpha 6 nicotinic acetylcholine receptors

http://www.wikidata.org/entity/Q24643170

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Cognitive enhancers for the treatment of ADHD Crucial roles of the CHRNB3-CHRNA6 gene cluster on chromosome 8 in nicotine dependence: update and subjects for future research Orthosteric and Allosteric Ligands of Nicotinic Acetylcholine Receptors for Smoking Cessation Molecular mechanisms underlying behaviors related to nicotine addiction Molecules and circuits involved in nicotine addiction: The many faces of smoking Preclinical evidence that activation of mesolimbic alpha 6 subunit containing nicotinic acetylcholine receptors supports nicotine addiction phenotype Mechanistic insights into nicotine withdrawal.Stable expression and functional characterization of a human nicotinic acetylcholine receptor with α6β2 properties: discovery of selective antagonists Behavioral and molecular analysis of nicotine-conditioned place preference in zebrafish Roles for N-terminal extracellular domains of nicotinic acetylcholine receptor (nAChR) β3 subunits in enhanced functional expression of mouse α6β2β3- and α6β4β3-nAChRs.Replicated Risk Nicotinic Cholinergic Receptor Genes for Nicotine Dependence.Significant associations of CHRNA2 and CHRNA6 with nicotine dependence in European American and African American populations Analysis of rare variations reveals roles of amino acid residues in the N-terminal extracellular domain of nicotinic acetylcholine receptor (nAChR) alpha6 subunit in the functional expression of human alpha6*-nAChRs.Insights into the neurobiology of the nicotinic cholinergic system and nicotine addiction from mice expressing nicotinic receptors harboring gain-of-function mutations Elimination of the vesicular acetylcholine transporter in the striatum reveals regulation of behaviour by cholinergic-glutamatergic co-transmission.Nicotinic receptor-mediated reduction in L-DOPA-induced dyskinesias may occur via desensitization Alpha-conotoxin MII-sensitive nicotinic acetylcholine receptors in the nucleus accumbens shell regulate progressive ratio responding maintained by nicotine.Altered activity-rest patterns in mice with a human autosomal-dominant nocturnal frontal lobe epilepsy mutation in the β2 nicotinic receptor.Cholinergic Mesopontine Signals Govern Locomotion and Reward through Dissociable Midbrain Pathways.Structural differences determine the relative selectivity of nicotinic compounds for native alpha 4 beta 2*-, alpha 6 beta 2*-, alpha 3 beta 4*- and alpha 7-nicotine acetylcholine receptors Indolizidine (-)-235B' and related structural analogs: discovery of nicotinic receptor antagonists that inhibit nicotine-evoked [3H]dopamine release Pre-clinical properties of the alpha4beta2 nicotinic acetylcholine receptor partial agonists varenicline, cytisine and dianicline translate to clinical efficacy for nicotine dependence.Differential expression and function of nicotinic acetylcholine receptors in subdivisions of medial habenula Molecular genetics and imaging technologies for circuit-based neuroanatomy.Progress and challenges in the study of α6-containing nicotinic acetylcholine receptors.Chrna4 A529 knock-in mice exhibit altered nicotine sensitivity.Presynaptic GABAB autoreceptor regulation of nicotinic acetylcholine receptor mediated [(3)H]-GABA release from mouse synaptosomes.Subtype-specific mechanisms for functional interaction between α6β4* nicotinic acetylcholine receptors and P2X receptors Acute ethanol inhibits dopamine release in the nucleus accumbens via α6 nicotinic acetylcholine receptors Acetylcholine as a neuromodulator: cholinergic signaling shapes nervous system function and behavior.Nicotinic receptor antagonists as treatments for nicotine abuse.Expression of functional human α6β2β3* acetylcholine receptors in Xenopus laevis oocytes achieved through subunit chimeras and concatamers.Menthol Alone Upregulates Midbrain nAChRs, Alters nAChR Subtype Stoichiometry, Alters Dopamine Neuron Firing Frequency, and Prevents Nicotine Reward.α2* Nicotinic acetylcholine receptors influence hippocampus-dependent learning and memory in adolescent mice.Functional nicotinic acetylcholine receptors containing α6 subunits are on GABAergic neuronal boutons adherent to ventral tegmental area dopamine neurons.bPiDI: a novel selective α6β2* nicotinic receptor antagonist and preclinical candidate treatment for nicotine abuse.Transcriptional regulation by nicotine in dopaminergic neurons.Distinct contributions of nicotinic acetylcholine receptor subunit alpha4 and subunit alpha6 to the reinforcing effects of nicotine.The necessity of α4* nicotinic receptors in nicotine-driven behaviors: dissociation between reinforcing and motor effects of nicotine.Effects of tobacco smoke constituents, anabasine and anatabine, on memory and attention in female rats.

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P2860

In vivo activation of midbrain dopamine neurons via sensitized, high-affinity alpha 6 nicotinic acetylcholine receptors

http://www.wikidata.org/entity/Q24643170

description

2008 nî lūn-bûn

@nan

2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

In vivo activation of midbrain ...... otinic acetylcholine receptors

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In vivo activation of midbrain ...... otinic acetylcholine receptors

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In vivo activation of midbrain ...... otinic acetylcholine receptors

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In vivo activation of midbrain ...... otinic acetylcholine receptors

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In vivo activation of midbrain ...... otinic acetylcholine receptors

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In vivo activation of midbrain ...... otinic acetylcholine receptors

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In vivo activation of midbrain ...... otinic acetylcholine receptors

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In vivo activation of midbrain ...... otinic acetylcholine receptors

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In vivo activation of midbrain ...... otinic acetylcholine receptors

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In vivo activation of midbrain ...... otinic acetylcholine receptors

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Henry A Lester

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J Michael McIntosh

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Julie M Miwa

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Merouane Bencherif

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Michael J Marks

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Nathaniel Heintz

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Paul Whiteaker

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Ryan M Drenan

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Sharon R Grady

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Sheri McKinney

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P2860

A new alpha-conotoxin which targets alpha3beta2 nicotinic acetylcholine receptors

Synthesis of 2-(pyridin-3-yl)-1-azabicyclo[3.2.2]nonane, 2-(pyridin-3-yl)-1-azabicyclo[2.2.2]octane, and 2-(pyridin-3-yl)-1-azabicyclo[3.2.1]octane, a class of potent nicotinic acetylcholine receptor-ligands

Subunit composition of functional nicotinic receptors in dopaminergic neurons investigated with knock-out mice

Palmitoylation regulates plasma membrane-nuclear shuttling of R7BP, a novel membrane anchor for the RGS7 family.

Hierarchical control of dopamine neuron-firing patterns by nicotinic receptors

Distribution and pharmacology of alpha 6-containing nicotinic acetylcholine receptors analyzed with mutant mice

Point mutant mice with hypersensitive alpha 4 nicotinic receptors show dopaminergic deficits and increased anxiety.

Nicotine activation of alpha4* receptors: sufficient for reward, tolerance, and sensitization

Executive and social behaviors under nicotinic receptor regulation

Getting formal with dopamine and reward

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