Structural basis of cargo membrane protein discrimination by the human COPII coat machinery
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Vesicle-mediated export from the ER: COPII coat function and regulationVesicle-mediated ER export of proteins and lipidsStructure of Coatomer Cage Proteins and the Relationship among COPI, COPII, and Clathrin Vesicle CoatsEpsin N-terminal homology domains bind on opposite sides of two SNAREsThe structure of the COPII transport-vesicle coat assembled on membranesDisruption of the Sec24d gene results in early embryonic lethality in the mouseGlobal defects in collagen secretion in a Mia3/TANGO1 knockout mouseMammalian COPII coat component SEC24C is required for embryonic development in miceSorting of GPI-anchored proteins into ER exit sites by p24 proteins is dependent on remodeled GPISEC24A deficiency lowers plasma cholesterol through reduced PCSK9 secretion.TANGO1/cTAGE5 receptor as a polyvalent template for assembly of large COPII coatsMutations in the main cytoplasmic loop of the GABA(A) receptor α4 and δ subunits have opposite effects on surface expression.ER retention is imposed by COPII protein sorting and attenuated by 4-phenylbutyrate.Sec24D-dependent transport of extracellular matrix proteins is required for zebrafish skeletal morphogenesis.Regulation of coat assembly--sorting things out at the ER.Nicotine up-regulates alpha4beta2 nicotinic receptors and ER exit sites via stoichiometry-dependent chaperoningCargo adaptors: structures illuminate mechanisms regulating vesicle biogenesis.The serotonin transporter is an exclusive client of the coat protein complex II (COPII) component SEC24C.The B7-1 cytoplasmic tail enhances intracellular transport and mammalian cell surface display of chimeric proteins in the absence of a linear ER export motif.Di-acidic motifs in the membrane-distal C termini modulate the transport of angiotensin II receptors from the endoplasmic reticulum to the cell surface.Sec24 is a coincidence detector that simultaneously binds two signals to drive ER exportCharacterizing functional α6β2 nicotinic acetylcholine receptors in vitro: mutant β2 subunits improve membrane expression, and fluorescent proteins reveal responsive cells.Mutations in SEC24D, encoding a component of the COPII machinery, cause a syndromic form of osteogenesis imperfectaKv1.3 contains an alternative C-terminal ER exit motif and is recruited into COPII vesicles by Sec24a.Sec24p and Sec16p cooperate to regulate the GTP cycle of the COPII coat.The [corrected] SEC23-SEC31 [corrected] interface plays critical role for export of procollagen from the endoplasmic reticulumA triple arg motif mediates α(2B)-adrenergic receptor interaction with Sec24C/D and export.Effect of simultaneously replacing putative TM6 and TM12 of human NBCe1-A with those from NBCn1 on surface abundance in Xenopus oocytesDual-targeting of Arabidopsis DMP1 isoforms to the tonoplast and the plasma membraneHistone Modifier Genes Alter Conotruncal Heart Phenotypes in 22q11.2 Deletion Syndrome.The highly conserved COPII coat complex sorts cargo from the endoplasmic reticulum and targets it to the golgi.Morpho-functional architecture of the Golgi complex of neuroendocrine cells.Identification of endoplasmic reticulum export motifs for G protein-coupled receptorsRegulation of α2B-Adrenerigc Receptor Export Trafficking by Specific MotifsA new class of endoplasmic reticulum export signal PhiXPhiXPhi for transmembrane proteins and its selective interaction with Sec24CCOPII - a flexible vesicle formation systemAn engineered glutamate-gated chloride (GluCl) channel for sensitive, consistent neuronal silencing by ivermectin.Sec24C/D-isoform-specific sorting of the preassembled ER-Golgi Q-SNARE complex.Conduits of life's spark: a perspective on ion channel research since the birth of neuron.The yeast Golgi apparatus: insights and mysteries.
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P2860
Structural basis of cargo membrane protein discrimination by the human COPII coat machinery
description
2008 nî lūn-bûn
@nan
2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Structural basis of cargo memb ...... the human COPII coat machinery
@ast
Structural basis of cargo memb ...... the human COPII coat machinery
@en
Structural basis of cargo memb ...... the human COPII coat machinery
@nl
type
label
Structural basis of cargo memb ...... the human COPII coat machinery
@ast
Structural basis of cargo memb ...... the human COPII coat machinery
@en
Structural basis of cargo memb ...... the human COPII coat machinery
@nl
prefLabel
Structural basis of cargo memb ...... the human COPII coat machinery
@ast
Structural basis of cargo memb ...... the human COPII coat machinery
@en
Structural basis of cargo memb ...... the human COPII coat machinery
@nl
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Structural basis of cargo memb ...... the human COPII coat machinery
@en
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Jonathan Goldberg
Joseph D Mancias
P2860
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10.1038/EMBOJ.2008.208
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P577
2008-11-05T00:00:00Z