DNA double-strand breaks activate a multi-functional genetic program in developing lymphocytes - Test2 - elhamkhani - TriplyDB

DNA double-strand breaks activate a multi-functional genetic program in developing lymphocytes

DNA double-strand breaks activate a multi-functional genetic program in developing lymphocytes

http://www.wikidata.org/entity/Q24644085

about

ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks ATM damage response and XLF repair factor are functionally redundant in joining DNA breaks Caspase 3/caspase-activated DNase promote cell differentiation by inducing DNA strand breaks DNA Damage: From Chronic Inflammation to Age-Related Deterioration Ataxia telangiectasia: a review The response to and repair of RAG-mediated DNA double-strand breaks RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci Histone H2AX stabilizes broken DNA strands to suppress chromosome breaks and translocations during V(D)J recombination A type I IFN-dependent DNA damage response regulates the genetic program and inflammasome activation in macrophages.Roles of the NF-kappaB pathway in lymphocyte development and function.Genetic variation in DNA repair pathways and risk of non-Hodgkin's lymphoma.BCL6 is critical for the development of a diverse primary B cell repertoire.Apurinic/apyrimidinic endonuclease 2 regulates the expansion of germinal centers by protecting against activation-induced cytidine deaminase-independent DNA damage in B cells.KAP-1 promotes resection of broken DNA ends not protected by γ-H2AX and 53BP1 in G₁-phase lymphocytes.Posttranscriptional silencing of VbetaDJbetaCbeta genes contributes to TCRbeta allelic exclusion in mammalian lymphocytes.Antigen receptor allelic exclusion: an update and reappraisal Ataxia telangiectasia-mutated protein and DNA-dependent protein kinase have complementary V(D)J recombination functions.DNA damage activates a complex transcriptional response in murine lymphocytes that includes both physiological and cancer-predisposition programs.Regulation of cell differentiation by the DNA damage response.H2AX prevents CtIP-mediated DNA end resection and aberrant repair in G1-phase lymphocytes.Unique and redundant functions of ATM and DNA-PKcs during V(D)J recombination Nuclear initiated NF-κB signaling: NEMO and ATM take center stage.Gammaherpesvirus gene expression and DNA synthesis are facilitated by viral protein kinase and histone variant H2AX.RAG-induced DNA double-strand breaks signal through Pim2 to promote pre-B cell survival and limit proliferation.MRN- and 9-1-1-Independent Activation of the ATR-Chk1 Pathway during the Induction of the Virulence Program in the Phytopathogen Ustilago maydis.DNA double-strand breaks relieve USF-mediated repression of Dβ2 germline transcription in developing thymocytes.Functional analysis of naturally occurring DCLRE1C mutations and correlation with the clinical phenotype of ARTEMIS deficiency Overlapping functions between XLF repair protein and 53BP1 DNA damage response factor in end joining and lymphocyte development Spatial organization of the mouse genome and its role in recurrent chromosomal translocations A broad range of self-reactivity drives thymic regulatory T cell selection to limit responses to self.Integrated signaling in developing lymphocytes: the role of DNA damage responses.RAG-mediated DNA double-strand breaks activate a cell type-specific checkpoint to inhibit pre-B cell receptor signals.The ataxia telangiectasia mutated kinase controls Igκ allelic exclusion by inhibiting secondary Vκ-to-Jκ rearrangements The ATM signaling network in development and disease.Lymphocyte development: integration of DNA damage response signaling.Bone marrow osteoblast vulnerability to chemotherapy AID hits the jackpot when missing the target.Silencing by nuclear matrix attachment distinguishes cell-type specificity: association with increased proliferation capacity.MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks Development of immunoglobulin lambda-chain-positive B cells, but not editing of immunoglobulin kappa-chain, depends on NF-kappaB signals.

P2860

Q24321489-964AE888-B47C-45C3-9219-A9868256B64C Q24596775-2A295D49-709F-474E-88B8-CD8E20C25857 Q24626183-C99E4E38-A2D1-478B-AFAD-6EFF1C9338F1 Q28078628-26D67312-31D9-47DE-8DF4-4AD0B92CA8D9 Q28079581-2B54EC78-88D8-46B4-B372-D4044C3B5FD9 Q28256889-F746ECAF-4167-4190-B153-6ED3314B3EE1 Q28508203-9B69A7DA-B08E-47F4-ADB3-E5C9E202C03C Q33591110-4BBB6734-9858-4AFF-A171-6BD339286803 Q33617275-B19A07E0-0F27-4E67-9DE8-CEB0FB14EB4B Q33800318-A013A476-4DA5-4DCD-B5AA-43803E4792A7 Q33882519-1D0F545B-F00B-41C4-84A5-706C59953EC9 Q33902336-F2269413-2F84-4AD9-9B35-4BE85C0A0883 Q33928805-DF95859F-3827-4F1D-9756-DCD1B79B13B6 Q34056461-3D27F967-E839-4960-BC1A-F97044F63DFD Q34061541-E6F107A4-5E3A-4A93-AB8F-643221966343 Q34432792-149A2F34-0701-4942-97A0-303A3B2BEE8A Q34549990-6C4F6704-F434-47E9-AD87-1C21A02DBAED Q34621580-88183D91-5203-4F87-B594-682835D27957 Q34949637-EE6329FD-B88E-4D17-8F54-35A28AC6722B Q35148396-B07057F9-BFD0-486E-81FD-1E17816D29BF Q35159001-DFFFC8B8-4B96-4F00-9A03-21447A0BCBD5 Q35347865-CA5E48F2-47A4-47FA-958F-92507A3C119C Q35479323-49B6D6C7-BF4E-4C59-9BE3-47DEFD22FE03 Q35679544-2B5D6D9D-16A8-47E2-B2DA-0B451F9E4840 Q35773337-C5C8359C-1F15-438D-AD9A-78F4EFBEFE2A Q35783972-CBF9F719-702D-4D30-BD6B-EAD460479554 Q35828383-D27384B2-FDFE-43F7-AD2E-F17E92213C81 Q35844884-DEC0F560-1362-4168-9078-8A040ACF60F5 Q35874015-B59FD8C6-380C-468F-BD61-76DC2170B10B Q36275699-82CCD4EC-3601-4519-9658-072DAD663EC4 Q36472229-FF09441A-461D-49A4-B513-3D18A2808129 Q36569363-1C4ED8EA-6902-43FA-9A8C-00C96BF61F03 Q36603553-1E64F5A3-F4D3-423A-8B75-70F77CD081A9 Q36712849-553370D5-5841-405F-A407-F295D8E4864A Q36846366-CB180820-4EB4-4BA2-AC0A-F2C25E5FD659 Q36870051-462F953C-8D4D-499B-A8E1-97ED8F78C470 Q37164471-542F9F8B-DC70-4575-B7AD-BDD59618AA95 Q37199529-6B8B84D4-3521-45E1-8DE2-1EC63B033AFB Q37234327-2737EB13-BB63-4E19-94AB-AC098C8E55FF Q37344357-97D76980-85C5-4CD0-A495-93CEA337BD02

P2860

DNA double-strand breaks activate a multi-functional genetic program in developing lymphocytes

http://www.wikidata.org/entity/Q24644085

description

2008 nî lūn-bûn

@nan

2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

name

DNA double-strand breaks activ ...... gram in developing lymphocytes

@ast

DNA double-strand breaks activ ...... gram in developing lymphocytes

@en

DNA double-strand breaks activ ...... gram in developing lymphocytes

@nl

type

label

DNA double-strand breaks activ ...... gram in developing lymphocytes

@ast

DNA double-strand breaks activ ...... gram in developing lymphocytes

@en

DNA double-strand breaks activ ...... gram in developing lymphocytes

@nl

prefLabel

DNA double-strand breaks activ ...... gram in developing lymphocytes

@ast

DNA double-strand breaks activ ...... gram in developing lymphocytes

@en

DNA double-strand breaks activ ...... gram in developing lymphocytes

@nl

P1433

Q24644085-4186E827-BF20-4457-9B35-9B8C613157DF

P1476

Q24644085-3E2B4022-C4FC-4973-8DD2-88E428E364B0

P2093

Q24644085-040A7425-6464-4C35-9F0B-C55A73B74652

Q24644085-1A9681D9-6147-4B45-AD2D-040A263A7CF4

Q24644085-3BB2117C-5371-4D57-BE1D-AA4C8D0C4319

Q24644085-4D753028-AA2B-4F94-A283-D8C3FBA3CFD3

Q24644085-5BB785F9-6E4C-49A6-9792-A02245CE2B76

Q24644085-6FF8B023-9903-4BA4-AB29-049A3219FC0F

Q24644085-97D4BA00-069A-42C1-B4AE-AE6CFD9E1D23

Q24644085-A86B0153-30CF-4EE6-8275-5B35CFAD1BB3

Q24644085-AB4A6698-D110-48CF-B517-AEF10387B00D

Q24644085-BECD0A54-8917-4944-ACB9-00655CCE64AD

P2860

Q24644085-092E66B0-0AE5-41E9-AD12-229F96A2DB21

Q24644085-0BEC1F0A-501E-4009-914F-1D3EB3F13755

Q24644085-0C57F7FE-D9C1-436D-956C-B0F8F3136373

Q24644085-0D446011-DBBD-4F70-9D8C-FE0211ED4AC3

Q24644085-15C7CDCE-8FCC-4A19-97A8-09FED095A250

Q24644085-176CD09F-EC30-44C2-9E9F-EC9021C6AA7D

Q24644085-208CC563-2DB7-44AE-8F88-978B447A7882

Q24644085-28F299C2-487F-4717-BDAE-515B6F952458

Q24644085-2A31EAE1-0A13-4F2F-8D60-A7F70DE03EEE

Q24644085-2C0A79F0-C993-4B77-B5A0-91FE73317035

P2888

Q24644085-FABAB456-9139-43EC-BACF-8593F32F2A87

P304

Q24644085-38E369AB-138D-42B5-A567-B346971EE201

P31

Q24644085-1D48FE4C-2EE2-40D5-984D-B80778491152

P3181

Q24644085-A7ED1466-C4A9-4117-A328-C3397F95E062

P356

Q24644085-99299AF6-28FD-4CCD-BA9F-7F8E421B060F

P407

Q24644085-8C0EE819-0697-4AEF-888D-ACAECA60BFF5

P433

Q24644085-A577D3F7-C74C-4078-9E2A-529B9760879A

P478

Q24644085-CF156F26-53B3-43F2-94F5-130164A4344E

P50

Q24644085-2237680C-3786-4906-8CF9-71E8BF6C25F9

Q24644085-5700962A-DC83-47AC-BED7-0D6BD0235C24

Q24644085-6C839F9F-C584-4005-9333-88EF11850FD8

Q24644085-F3F0B5CB-27E1-4FB1-AFB5-AB2F810FBC02

P577

Q24644085-37B6C915-3902-46D7-B2E4-4A731CF2C9D6

P5875

Q24644085-63946453-7643-43AC-84FE-22A2E15B6D46

P6179

Q24644085-117D5E90-5990-408B-AFD5-69061A9AD9D6

P698

Q24644085-5B8364FC-8E24-4245-B956-B257BE8218E3

P932

Q24644085-C1CA6AD3-8D7C-4094-8501-0D456C586F3C

P3181

P356

P1433

P1476

DNA double-strand breaks activ ...... gram in developing lymphocytes

@en

P2093

Barry P Sleckman

http://www.w3.org/2001/XMLSchema#string

Beth A Helmink

http://www.w3.org/2001/XMLSchema#string

Brian K Weaver

http://www.w3.org/2001/XMLSchema#string

Craig H Bassing

http://www.w3.org/2001/XMLSchema#string

Cynthia L Innes

http://www.w3.org/2001/XMLSchema#string

Eric J Gapud

http://www.w3.org/2001/XMLSchema#string

Grace K Mahowald

http://www.w3.org/2001/XMLSchema#string

Jennifer B Collins

http://www.w3.org/2001/XMLSchema#string

Laura M Walker

http://www.w3.org/2001/XMLSchema#string

Laura Mandik-Nayak

http://www.w3.org/2001/XMLSchema#string

P2860

Expression of the Bcl-3 proto-oncogene suppresses p53 activation

Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress

Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation

The DNA damage response: putting checkpoints in perspective

Selective inhibition of NF-kappaB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complex

The RAG proteins and V(D)J recombination: complexes, ends, and transposition

Integrating cell-signalling pathways with NF-kappaB and IKK function

Leaky Scid phenotype associated with defective V(D)J coding end processing in Artemis-deficient mice

ATM and related protein kinases: safeguarding genome integrity

Signaling to NF-kappaB

P2888

P304

819-823

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

2805677

http://www.w3.org/2001/XMLSchema#string

P356

10.1038/NATURE07392

http://www.w3.org/2001/XMLSchema#string

P407

P433

7223

http://www.w3.org/2001/XMLSchema#string

P478

456

http://www.w3.org/2001/XMLSchema#string

P50

Andrea L. Bredemeyer

P577

2008-10-12T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

23312328

http://www.w3.org/2001/XMLSchema#string

P6179

1027021013

http://www.w3.org/2001/XMLSchema#string

P698

18849970

http://www.w3.org/2001/XMLSchema#string

P932

2605662

http://www.w3.org/2001/XMLSchema#string