A transcriptional mediator protein that is required for activation of many RNA polymerase II promoters and is conserved from yeast to humans
about
The human homologue of Drosophila TRF-proximal protein is associated with an RNA polymerase II-SRB complexA yeast four-hybrid system identifies Cdk-activating kinase as a regulator of the XPD helicase, a subunit of transcription factor IIHA human RNA polymerase II complex containing factors that modify chromatin structureThe Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domainMammalian mediator of transcriptional regulation and its possible role as an end-point of signal transduction pathwaysSrb7p is essential for the activation of a subset of genes.RNA polymerase subunit RPB5 plays a role in transcriptional activationMed9/Cse2 and Gal11 modules are required for transcriptional repression of distinct group of genes.Saccharomyces cerevisiae Med9 comprises two functionally distinct domains that play different roles in transcriptional regulation.Activator-specific requirement of yeast mediator proteins for RNA polymerase II transcriptional activation.Hrs1/Med3 is a Cyc8-Tup1 corepressor target in the RNA polymerase II holoenzyme.The Med1 subunit of the yeast mediator complex is involved in both transcriptional activation and repression.Loss of the Rpb4/Rpb7 subcomplex in a mutant form of the Rpb6 subunit shared by RNA polymerases I, II, and III.Identification of new mediator subunits in the RNA polymerase II holoenzyme from Saccharomyces cerevisiae.Mediator--a universal complex in transcriptional regulationMolecular genetics of the RNA polymerase II general transcriptional machineryYeast carbon catabolite repressionRequirement for a functional interaction between mediator components Med6 and Srb4 in RNA polymerase II transcriptionInterplay of positive and negative regulators in transcription initiation by RNA polymerase II holoenzyme.Analysis of Schizosaccharomyces pombe mediator reveals a set of essential subunits conserved between yeast and metazoan cells.Drosophila Med6 is required for elevated expression of a large but distinct set of developmentally regulated genesRNA polymerase II holoenzymes and subcomplexes.Topoisomerase III is required for accurate DNA replication and chromosome segregation in Schizosaccharomyces pombeIndependent recruitment of mediator and SAGA by the activator Met4Mediator protein mutations that selectively abolish activated transcriptionTranscriptional regulation: contending with complexityRole for human mediator subunit MED25 in recruitment of mediator to promoters by endoplasmic reticulum stress-responsive transcription factor ATF6α.Mechanisms of Mediator complex action in transcriptional activation.An activator binding module of yeast RNA polymerase II holoenzymeA multiplicity of mediators: alternative forms of transcription complexes communicate with transcriptional regulators.Functional correlation among Gal11, transcription factor (TF) IIE, and TFIIH in Saccharomyces cerevisiae. Gal11 and TFIIE cooperatively enhance TFIIH-mediated phosphorylation of RNA polymerase II carboxyl-terminal domain sequences.Preponderance of free mediator in the yeast Saccharomyces cerevisiae.The MED-7 transcriptional mediator encoded by let-49 is required for gonad and germ cell development in Caenorhabditis elegans.
P2860
Q22001483-18B480A1-2C2D-4D8D-8E9A-47A47015DA08Q24291428-11D0089C-D1F7-428A-86FE-550ADBCC8424Q24522669-4CE805EA-E256-423A-86DB-50180161077FQ24609120-574DBC7C-4EE7-4DDC-9E84-E18FC6EAD310Q24681762-CF16AF4D-B673-4004-83F5-A826B76C7DC6Q27930238-E102A480-7684-4A93-87D2-7670818C5D28Q27931093-EBDCE9AB-6EB0-447D-BF42-402E65910B9AQ27933388-81749CAB-8EF8-4B5D-8541-7495520A636EQ27933777-B73485D1-B09B-46C7-A9A8-7DB4E3DE0128Q27933836-C21ED440-9733-4A9A-ACBA-3D6950A92B1AQ27934566-00EDCF11-E1FA-450A-819C-05A057401B54Q27937894-F534A792-63FE-48F7-B1F7-3E7803BE7D71Q27938792-2F00C04B-6EEB-4EE4-89E8-26D92948746EQ27940073-9AA76B93-D39F-4A4B-9EC1-0DAD5C52227AQ28206442-3EC24205-B651-46FD-A4DD-DECC6B109259Q29620260-7CD78CA0-48F8-4CAB-9463-8E073511E9FCQ29622932-DC53AEEA-A0FF-4E7D-9265-98621697E983Q32036964-AD06E808-CC60-4BDC-9A55-CCD5013F50C6Q33775117-4B4F2780-FDF6-4747-9E0D-D956B1E23FB6Q33946934-A7E29392-AF4F-4A65-A813-9DDCAED12EC5Q33969120-D760F639-CD04-4D9B-8221-A77C27701C70Q34067671-B0F8F2C4-F0EE-4808-9E7A-059AB5FC1544Q34367583-8AB2D153-F8D5-4A9A-B3D4-056C57AC2100Q34563248-1C7FF8A0-9C61-49F8-AE86-7CB334590DB8Q34790743-A87FB8B1-74C2-4E3A-B9FC-5741321F9D92Q35964659-E52AE248-DDC3-441E-A770-8BC5F56A5469Q37151090-8B08D084-568D-4D68-BBFC-EB861EE0E635Q38077643-09693762-4019-46F4-8912-79F89DDC20E2Q39445291-A0580359-C5F7-4312-8629-5228B96EEC03Q39722071-4F049A51-610E-452C-B265-5B14DD67ABDEQ42453747-C1591D14-44AE-4488-B04E-AC3EE1AE809BQ44560693-7576CB89-47EC-49BC-9DA9-5D193E335D53Q48874029-FB85CCA8-6F87-434F-8695-F74C05257CDE
P2860
A transcriptional mediator protein that is required for activation of many RNA polymerase II promoters and is conserved from yeast to humans
description
1997 nî lūn-bûn
@nan
1997 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
name
A transcriptional mediator pro ...... conserved from yeast to humans
@ast
A transcriptional mediator pro ...... conserved from yeast to humans
@en
A transcriptional mediator pro ...... conserved from yeast to humans
@nl
type
label
A transcriptional mediator pro ...... conserved from yeast to humans
@ast
A transcriptional mediator pro ...... conserved from yeast to humans
@en
A transcriptional mediator pro ...... conserved from yeast to humans
@nl
prefLabel
A transcriptional mediator pro ...... conserved from yeast to humans
@ast
A transcriptional mediator pro ...... conserved from yeast to humans
@en
A transcriptional mediator pro ...... conserved from yeast to humans
@nl
P2093
P2860
P356
P1476
A transcriptional mediator pro ...... conserved from yeast to humans
@en
P2093
P2860
P304
P356
10.1128/MCB.17.8.4622
P407
P577
1997-08-01T00:00:00Z