A subpopulation of neuronal M4 muscarinic acetylcholine receptors plays a critical role in modulating dopamine-dependent behaviors
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Leveraging the cortical cholinergic system to enhance attentionAn allosteric enhancer of M₄ muscarinic acetylcholine receptor function inhibits behavioral and neurochemical effects of cocaineCaMKII hunkers down on the muscarinic M4 receptor to help curb cocaine-induced hyperlocomotionAlzheimer's disease: Targeting the Cholinergic SystemBalanced NMDA receptor activity in dopamine D1 receptor (D1R)- and D2R-expressing medium spiny neurons is required for amphetamine sensitizationSelective activation of M4 muscarinic acetylcholine receptors reverses MK-801-induced behavioral impairments and enhances associative learning in rodents.Antipsychotic drug-like effects of the selective M4 muscarinic acetylcholine receptor positive allosteric modulator VU0152100Muscarinic and nicotinic acetylcholine receptor agonists and allosteric modulators for the treatment of schizophreniaElimination of the vesicular acetylcholine transporter in the striatum reveals regulation of behaviour by cholinergic-glutamatergic co-transmission.Increased cocaine self-administration in M4 muscarinic acetylcholine receptor knockout mice.Muscarinic Acetylcholine Receptor Subtypes as Potential Drug Targets for the Treatment of Schizophrenia, Drug Abuse and Parkinson's DiseaseContribution of both M1 and M4 receptors to muscarinic agonist-mediated attenuation of the cocaine discriminative stimulus in mice.Sensing Positive versus Negative Reward Signals through Adenylyl Cyclase-Coupled GPCRs in Direct and Indirect Pathway Striatal Medium Spiny Neurons.Dopaminergic and cholinergic regulation of Fyn tyrosine kinase phosphorylation in the rat striatum in vivo.Effects of dopamine D1-like and D2-like antagonists on cocaine discrimination in muscarinic receptor knockout mice.M4 Muscarinic Receptor Signaling Ameliorates Striatal Plasticity Deficits in Models of L-DOPA-Induced DyskinesiaCocaine-induced adaptations in D1 and D2 accumbens projection neurons (a dichotomy not necessarily synonymous with direct and indirect pathways).δ-opioid and dopaminergic processes in accumbens shell modulate the cholinergic control of predictive learning and choice.Cholinergic contributions to the cognitive symptoms of schizophrenia and the viability of cholinergic treatmentsUtility of genetically modified mice for understanding the neurobiology of substance use disorders.Neuromodulatory control of striatal plasticity and behavior.The striatal balancing act in drug addiction: distinct roles of direct and indirect pathway medium spiny neurons.Unraveling the differential functions and regulation of striatal neuron sub-populations in motor control, reward, and motivational processesEmerging approaches for treatment of schizophrenia: modulation of cholinergic signaling.Activation of M1 and M4 muscarinic receptors as potential treatments for Alzheimer's disease and schizophreniaMuscarinic acetylcholine receptors: novel opportunities for drug development.A threshold model for opposing actions of acetylcholine on reward behavior: Molecular mechanisms and implications for treatment of substance abuse disorders.Striatal cholinergic interneurons and Parkinson's disease.Antipsychotic-induced catalepsy is attenuated in mice lacking the M4 muscarinic acetylcholine receptor.Spontaneous Synaptic Activation of Muscarinic Receptors by Striatal Cholinergic Neuron Firing.Physiological roles of CNS muscarinic receptors gained from knockout mice.Microbial antigen encounter during a preweaning interval is critical for tolerance to gut bacteria.Effects of muscarinic M1 and M4 acetylcholine receptor stimulation on extinction and reinstatement of cocaine seeking in male mice, independent of extinction learning.Positive allosteric modulation of M1 and M4 muscarinic receptors as potential therapeutic treatments for schizophrenia.Neuropeptide Y Y5 receptor antagonism attenuates cocaine-induced effects in mice.Age-dependent dystonia in striatal Gγ7 deficient mice is reversed by the dopamine D2 receptor agonist pramipexole.Synthesis of novel and functionally selective non-competitive muscarinic antagonists as chemical probes.Involvement of insular muscarinic cholinergic receptors in morphine-induced conditioned place preference in rats.Novel long-acting antagonists of muscarinic ACh receptors.The striatal cholinergic system in L-dopa-induced dyskinesias.
P2860
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P2860
A subpopulation of neuronal M4 muscarinic acetylcholine receptors plays a critical role in modulating dopamine-dependent behaviors
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
A subpopulation of neuronal M4 ...... g dopamine-dependent behaviors
@ast
A subpopulation of neuronal M4 ...... g dopamine-dependent behaviors
@en
A subpopulation of neuronal M4 ...... g dopamine-dependent behaviors
@nl
type
label
A subpopulation of neuronal M4 ...... g dopamine-dependent behaviors
@ast
A subpopulation of neuronal M4 ...... g dopamine-dependent behaviors
@en
A subpopulation of neuronal M4 ...... g dopamine-dependent behaviors
@nl
prefLabel
A subpopulation of neuronal M4 ...... g dopamine-dependent behaviors
@ast
A subpopulation of neuronal M4 ...... g dopamine-dependent behaviors
@en
A subpopulation of neuronal M4 ...... g dopamine-dependent behaviors
@nl
P2093
P2860
P1476
A subpopulation of neuronal M4 ...... g dopamine-dependent behaviors
@en
P2093
Albert A Davis
Allan I Levey
Anders Fink-Jensen
Chu-Xia Deng
Cuiling Li
David P D Woldbye
Ditte Dencker
Gitta Wörtwein
Günther Schütz
P2860
P304
P356
10.1523/JNEUROSCI.3843-09.2010
P407
P577
2010-02-10T00:00:00Z